Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine

Peptides

Volumn 21, Issue 8, 2000, Pages 1215-1221

  Ueda, Hiroshi ^a   Matsunaga, Shinobu ^a   Inoue, Makoto ^a   Yamamoto, Yukio ^b   Hazato, Tadahiko ^b  

^a NAGASAKI UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

2 MeS ATP; Bradykinin; Gi; P2X3; PGI2 agonist; Spinorphin

Indexed keywords

3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; DIZOCILPINE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; MORPHINE; NEUROPEPTIDE; PERTUSSIS TOXIN; PURINERGIC RECEPTOR STIMULATING AGENT; SPINORPHIN;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME DEGRADATION; EXOCYTOSIS; MOUSE; NEUTROPHIL CHEMOTAXIS; NOCICEPTION; NONHUMAN; POLYMORPHONUCLEAR CELL; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; RECEPTOR BLOCKING; SENSORY NERVE CELL; STIMULUS RESPONSE;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ADENOSINE; ANALGESICS, OPIOID; ANIMAL; ANIMALS, NEWBORN; BRADYKININ; CAPSAICIN; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MICE; MORPHINE; NEURONS, AFFERENT; NEUROPROTECTIVE AGENTS; OLIGOPEPTIDES; PAIN; PIPERIDINES; PROTEASE INHIBITORS; RECEPTORS, PURINERGIC; SUPPORT, NON-U.S. GOV'T; THIONUCLEOSIDES; TIME FACTORS; VIRULENCE FACTORS, BORDETELLA;

EID: 0033782234     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(00)00262-X     Document Type: Article

References (22)

1. Christiansen N.O. Pertussis toxin inhibits the FMLP-induced membrane association of protein kinase C in human neutrophils. J Leukoc Biol. 47:1990;60-63.
2. Erchegyi J., Kastin A.J., Zadina J.E., Qiu X.D. Isolation of a heptapeptide Val-Val-Tyr-Pro-Trp-Thr-Gln (valorphin) with some opiate activity. Int J Pept Protein Res. 39:1992;477-484.
3. Glamsta E.L., Marklund A., Hellman U., Wernstedt C., Terenius L., Nyberg F. Isolation and characterization of a hemoglobin-derived opioid peptide from the human pituitary gland. Regul Pept. 34:1991;169-179.
4. Hamilton S.G., Wade A., McMahon S.B. The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat. Br J Pharmacol. 126:1999;326-332.
5. Hazato T. [Enkephalin, and endogenous enkephalinase inhibitor]. Seikagaku. 66:1994;57-60.
6. Hiura A., Ishizuka H. Changes in features of degenerating primary sensory neurons with time after capsaicin treatment. Acta Neuropathol. (Berl). 78:1989;35-46.
7. Inoue M., Kobayashi M., Kozaki S., Zimmer A., Ueda H. Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice. Proc Natl Acad Sci USA. 95:1998;10949-10953.
8. Inoue M., Nakayamada H., Tokuyama S., Ueda H. Peripheral non-opioid analgesic effects of kyotorphin in mice. Neurosci Lett. 236:1997;60-62.
9. Inoue M., Shimohira I., Yoshida A., Zimmer A., Takeshima H., Ueda H. Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord. J Pharmacol Exp Ther. 291:1999;308-313.
10. Inoue M., Tokuyama S., Nakayamada H., Ueda H. In vivo signal transduction of tetrodotoxin-sensitive nociceptive responses by substance P given into the planta of mouse hind limb. Cell Mol Neurobiol. 18:1998;555-561.
11. Kunapuli S.P., Daniel J.L. P2 receptor subtypes in the cardiovascular system. Biochem J. 336:1998;513-523.
12. Liang S.L., Woodlock T.J., Whitin J.C., Lichtman M.A., Segel G.B. Signal transduction in N-formyl-methionyl-leucyl-phenylalanine and concanavalin A stimulated human neutrophils superoxide production without a rise in intracellular free calcium . J Cell Physiol. 145:1990;295-302.
13. Murata T., Ushikubi F., Matsuoka T., et al. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature. 388:1997;678-682.
14. 1 purinergic receptors in sensory neurons contribution to touch-induced impulse generation . Proc Natl Acad Sci USA. 93:1996;10465-10470.
15. Nishimura K., Hazato T. Isolation and identification of an endogenous inhibitor of enkephalin-degrading enzymes from bovine spinal cord. Biochem Biophys Res Commun. 194:1993;713-719.
16. Nishimura K., Hazato T. [Spinorphin, a new inhibitor of enkephalin-degrading enzymes derived from the bovine spinal cord]. Masui. 42:1993;1497-1503.
17. Nishimura K., Ueki M., Kaneto H., Hazato T. [Study of a new endogenous inhibitor of enkephalin-degrading enzymes; pharmacological function and metabolism of spinorphin]. Masui. 42:1993;1663-1670.
18. Ueda H. In vivo molecular signal transduction of peripheral mechanisms of pain. Jpn J Pharmacol. 79:1999;263-268.
19. Ueno S., Tsuda M., Iwanaga T., Inoue K. Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons. Br J Pharmacol. 126:1999;429-436.
20. Yamamoto Y., Kanazawa H., Shimamura M., Ueki M., Hazato T. Inhibitory action of spinorphin, an endogenous regulator of enkephalin-degrading enzymes, on carrageenan-induced polymorphonuclear neutrophil accumulation in mouse air-pouches. Life Sci. 62:1998;1767-1773.
21. 2- generation, and exocytosis by N-formylmethionyl-leucyl-phenylalanine (FMLP)-stimulated neutrophils. Biochem Pharmacol. 54:1997;695-701.
22. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:1983;109-110.