The global transcriptional maturation program and stimuli-specific gene expression profiles of human myeloid dendritic cells

International Immunology

Volumn 15, Issue 4, 2003, Pages 491-503

  Messmer, Davorka ^a   Messmer, Bradley ^a   Chiorazzi, Nicholas ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activation; CD40 ligand; Gene expression profile; Inflammatory cytokines; Lipopolysaccharide; Prostaglandin E2

Indexed keywords

CD40 LIGAND; CHEMOKINE; CYTOKINE; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2;

BONE MARROW CELL; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; DENDRITIC CELL; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; GENOME ANALYSIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MONOCYTE; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PRIORITY JOURNAL; REVIEW; UNINDEXED SEQUENCE;

CD40 LIGAND; CELL DIFFERENTIATION; CYTOKINES; DENDRITIC CELLS; GENE EXPRESSION PROFILING; HUMANS; LIPOPOLYSACCHARIDES; MYELOID CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0037386343     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg052     Document Type: Review

References (56)

1. O'Doherty, U., Peng, M., Gezelter, S., Swiggard, W. J., Betjes, M., Bhardwaj, N. and Steinman, R. M. 1994. Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. Immunology 82:487.
2. Arpin, C., de Bouteiller, O., Razanajaona, D., Fugier-Vivier, I., Briere, F., Banchereau, J., Lebecque, S. and Liu, Y. J. 1998. The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expression. J. Exp. Med. 187:1169.
3. Weissman, D., Li, Y., Ananworanich, J., Zhou, L. J., Adelsberger, J., Tedder, T. F., Baseler, M. and Fauci, A. S. 1995. Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1. Proc. Natl Acad. Sci. USA 92:826.
4. Lechmann, M., Berchtold, S., Steinkasserer, A. and Hauber, J. 2002. CD83 on dendritic cells: more than just a marker for maturation. Trends Immunol. 23:273.
5. Rissoan, M. C., Soumelis, V., Kadowaki, N., Grouard, G., Briere, F., de Waal Malefyt, R. and Liu, Y. J. 1999. Reciprocal control of T helper cell and dendritic cell differentiation [see Comments]. Science 283:1183.
6. Liu, Y. J., Kanzler, H., Soumelis, V. and Gilliet, M. 2001. Dendritic cell lineage, plasticity and cross-regulation. Nat. Immunol. 2:585.
7. Pulendran, B., Banchereau, J., Maraskovsky, E. and Maliszewski, C. 2001. Modulating the immune response with dendritic cells and their growth factors. Trends Immunol. 22:41.
8. Shortman, K. and Liu, Y. J. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2:151.
9. Mellman, I. and Steinman, R. M. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106:255.
10. Cella, M., Jarrossay, D., Facchetti, F., Alebardi, O., Nakajima, H., Lanzavecchia, A. and Colonna, M. 1999. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon [see Comments]. Nat. Med. 5:919.
11. Morelli, A. E., Zahorchak, A. F., Larregina, A. T., Colvin, B. L., Logar, A. J., Takayama, T., Falo, L. D. and Thomson, A. W. 2001. Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation. Blood 98:1512.
12. Dietz, A. B., Bulur, P. A., Knutson, G. J., Matasic, R. and Vuk-Pavlovic, S. 2000. Maturation of human monocyte-derived dendritic cells studied by microarray hybridization. Biochem. Biophys. Res. Commun. 275:731.
13. Granucci, F., Vizzardelli, C., Pavelka, N., Feau, S., Persico, M., Virzi, E., Rescigno, M., Moro, G. and Ricciardi-Castagnoli, P. 2001. Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nat. Immunol. 2:882.
14. Granucci, F., Vizzardelli, C., Virzi, E., Rescigno, M. and Ricciardi-Castagnoli, P. 2001. Transcriptional reprogramming of dendritic cells by differentiation stimuli. Eur. J. Immunol. 31:2539.
15. Huang, Q., Liu, D., Majewski, P., Schulte, L. C., Korn, J. M., Young, R. A., Lander, E. S. and Hacohen, N. 2001. The plasticity of dendritic cell responses to pathogens and their components. Science 294:870.
16. Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., et al. 2001. Initial sequencing and analysis of the human genome. Nature 409:860-921.
17. Lane, P., Brocker, T., Hubele, S., Padovan, E., Lanzavecchia, A. and McConnell, F. 1993. Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation. J. Exp. Med. 177:1209.
18. Li, C. and Wong, W. H. 2001. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc. Natl Acad. Sci. USA 98:31.
19. Gallucci, S., Lolkema, M. and Matzinger, P. 1999. Natural adjuvants: endogenous activators of dendritic cells. Nat. Med. 5:1249.
20. Jonuleit, H., Kuhn, U., Muller, G., Steinbrink, K., Paragnik, L., Schmitt, E., Knop, J. and Enk, A. H. 1997. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 27:3135.
21. + T cells for efficient tumor cell lysis. Cancer Res. 60:4446.
22. Triantafilou, M. and Triantafilou, K. 2002. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol. 23:301.
23. Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Kooten, C., Durand, I. and Banchereau, J. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263.
24. + hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J. Exp. Med. 185:341
25. Kuniyoshi, J. S., Kuniyoshi, C. J., Lim, A. M., Wang, F. Y., Bade E. R., Lau, R., Thomas, E. K. and Weber, J. S. 1999. Dendritic cell secretion of IL-15 is induced by recombinant huCD40LT and augments the stimulation of antigen-specific cytolytic T cells. Cell. Immunol. 193:48.
26. McDyer, J. F., Dybul, M., Goletz, T. J., Kinter, A. L., Thomas, E. K., Berzofsky, J. A., Fauci, A. S. and Seder, R. A. 1999. Differential effects of CD40 ligand/trimer stimulation on the ability of dendritic cells to replicate and transmit HIV infection: evidence for CC-chemokine-dependent and -independent mechanisms. J. Immunol. 162:3711.
27. Mosca, P. J., Hobeika, A. C., Clay, T. M., Nair, S. K., Thomas, E. K., Morse, M. A. and Lyerly, H. K. 2000. A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment. Blood 96:3499.
28. Mehlhop, E., Villamide, L. A., Frank, I., Gettie, A., Santisteban, C., Messmer, D., Ignatius, R., Lifson, J. D. and Pope, M. 2002. Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses. J. Immunol. Methods 260:219.
29. Snijders, A., Kalinski, P., Hilkens, C. M. and Kapsenberg, M. L. 1998. High-level IL-12 production by human dendritic cells requires two signals. Int. Immunol. 10:1593.
30. Sallusto, F., Palermo, B., Lenig, D., Miettinen, M., Matikainen, S., Julkunen, I., Forster, R., Burgstahler, R., Lipp, M. and Lanzavecchia, A. 1999. Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur. J. Immunol. 29:1617.
31. Bogdan, C. 2000. The function of type I interferons in antimicrobial immunity. Curr. Opin. Immunol. 12:419.
32. Cella, M., Salio, M., Sakakibara, Y., Langen, H., Julkunen, I. and Lanzavecchia, A. 1999. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189:821.
33. + T cells. J. Immunol. 165:1182.
34. Resta, R. and Thompson, L. F. 1997. SCID: the role of adenosine deaminase deficiency. Immunol. Today 18:371.
35. Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Kooten, C., Durand, I. and Banchereau, J. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263.
36. Wong, B. R., Josien, R., Lee, S. Y., Sauter, B., Li, H. L., Steinman, R. M. and Choi, Y. 1997. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186:2075.
37. Thiel, M., Chambers, J. D., Chouker, A., Fischer, S., Zourelidis, C., Bardenheuer, H. J., Arfors, K. E. and Peter, K. 1996. Effect of adenosine on the expression of beta(2) integrins and L-selectin of human polymorphonuclear leukocytes in vitro. J. Leukoc. Biol. 59:671.
38. Ma, H., Calderon, T. M., Fallon, J. T. and Berman, J. W. 2002. Hepatocyte growth factor is a survival factor for endothelial cells and is expressed in human atherosclerotic plaques. Atherosclerosis 164:79.
39. Kurz, S. M., Diebold, S. S., Hieronymus, T., Gust, T. C., Bartunek, P., Sachs, M., Birchmeier, W. and Zenke. M. 2002. The impact of c-met/scatter factor receptor on dendritic cell migration. Eur. J. Immunol. 32:1832.
40. Barclay, A. N. 1981. Different reticular elements in rat lymphoid tissue identified by localization of la, Thy-1 and MRC OX 2 antigens. Immunology 44:727.
41. Barclay, A. N., Wright, G. J., Brooke, G. and Brown, M. H. 2002. CD200 and membrane protein interactions in the control of myeloid cells. Trends Immunol. 23:285.
42. Gorczynski, R. M., Yu, K. and Clark, D. 2000. Receptor engagement on cells expressing a ligand for the tolerance-inducing molecule OX2 induces an immunoregulatory population that inhibits alloreactivity in vitro and in vivo. J. Immunol. 165:4854.
43. Dong, H., Zhu, G., Tamada, K. and Chen, L. 1999. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5:1365.
44. Freeman. G, J., Long, A. J., Iwai, Y., Bourque, K., Chernova, T., Nishimura, H., Fitz, L. J., Malenkovich, N., Okazaki, T., Byrne, M. C., Horton, H. F., Fouser, L., Carter, L., Ling, V., Bowman, M. R., Carreno, B. M., Collins, M., Wood, C. R. and Honjo, T. 2000. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192:1027.
45. Banchereau, J. and Steinman, R. M. 1998. Dendritic cells and the control of immunity. Nature 392:245.
46. D'Andrea, A., Rengaraju, M., Valiante, N. M., Chehimi, J., Kubin, M., Aste, M., Chan, S. H., Kobayashi, M., Young, D. and Nickbarg, E. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J. Exp. Med. 176:1387.
47. Foti, M., Granucci, F., Aggujaro, D., Liboi, E., Luini, W., Minardi, S., Mantovani, A., Sozzani, S. and Ricciardi-Castagnoli, P. 1999. Upon dendritic cell (DC) activation chemokines and chemokine receptor expression are rapidly regulated for recruitment and maintenance of DC at the inflammatory site. Int. Immunol. 11:979.
48. Yoshida, R., Nagira, M., Kitaura, M., Imagawa, N., Imai, T. and Yoshie, O. 1998. Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. J. Biol. Chem. 273:7118.
49. Adema, G. J., Hartgers, F., Verstraten, R., de Vries, E., Marland, G., Menon, S., Foster, J., Xu, Y., Nooyen, P., McClanahan, T., Bacon, K. B. and Figdor, C. G. 1997. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 387:713.
50. Schall, T. J., Bacon, K., Toy, K. J. and Goeddel, D. V. 1990. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347:669.
51. Enomoto, M., Nagayama, H. and Takahashi, T. A. 2001. Enhancement of migratory and aggregate activities of human peripheral blood monocyte-derived dendritic cells by stimulation with RANTES. Microbiol. Immunol. 45:639.
52. Zhu, K., Shen, Q., Ulrich, M. and Zheng, M. 2000. Human monocyte-derived dendritic cells expressing both chemotactic cytokines IL-8, MCP-1, RANTES and their receptors, and their selective migration to these chemokines. Chin. Med. J. (Engl.) 113:1124.
53. Youn, B. S., Zhang, S. M., Broxmeyer, H. E., Cooper, S., Antol, K., Fraser, M. and Kwon, B. S. 1998. Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1. Blood 91:3118.
54. Challita Eid, P. M., Abboud, C. N., Morrison, S. L., Penichet, M. L., Rosell, K. E., Poles, T., Hilchey, S. P., Planelles, V. and Rosenblatt, J. D. 1998. A RANTES-antibody fusion protein retains antigen specificity and chemokine function. J. Immunol. 161:3729.
55. Taub, D. D., Sayers, T. J., Carter, C. R. and Ortaldo, J. R. 1995. Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. J. Immunol. 155:3877.
56. Matzinger, P. 2002. The danger model: a renewed sense of self. Science 296:301.