Characterization of CKβ8 and CKβ8-1: Two alternatively spliced forms of human β-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1

Blood

Volumn 91, Issue 9, 1998, Pages 3118-3126

  Youn, Byung S ^b   Zhang, Shang M ^b   Broxmeyer, Hal E ^b   Cooper, Scott ^b   Antol, Kathleen ^b   Fraser Jr , Malcolm ^b   Kwon, Byoung S ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; BETA CHEMOKINE; CALCIUM; CHEMOKINE RECEPTOR; COMPLEMENTARY DNA;

AMINO ACID SEQUENCE; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; GROWTH REGULATION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LEUKOCYTE ACTIVATION; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; RNA SPLICING; ALTERNATIVE RNA SPLICING; CELL CULTURE; CHROMOSOME 17; EXON; GENE; GENETICS; INTRON; LYMPHOCYTE; MOLECULAR GENETICS; MONOCYTE; NEUTROPHIL; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ALTERNATIVE SPLICING; BASE SEQUENCE; CALCIUM; CELLS, CULTURED; CHEMOKINES, CC; CHEMOTAXIS, LEUKOCYTE; CHROMOSOMES, HUMAN, PAIR 17; DNA, COMPLEMENTARY; EXONS; GENES; HUMANS; INTRONS; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; MONOCYTES; NEUTROPHILS; RECEPTORS, CHEMOKINE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032056368     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.9.3118.3118_3118_3126     Document Type: Article

References (30)

1. Baggiolini M, Dahinden CA: CC chemokines in allergie inflammation. Immunol Today 15:127, 1994
2. Keiner SG, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ, Zlotnik A: Lymphotactin: A cytokine that represents a new class of chemokine. Science 266:1395, 1994
3. 3C motif. Nature 385:640, 1997
4. + T cells. Science 270:1811, 1995
5. Wolpe SD, Davatelis G, Sherry B, Beutler B, Hesse DG, Nguyen HT, Moldawer LL, Nathan CF, Lowry SF, Cerami A: Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J Exp Med 167:570, 1988
6. Graham GJ, Wright EG, Hewick R, Wolpe SD, Wilke NM, Donaldson D, Lorimore S, Pragnell IB: Identification and characterization of an inhibitor of haemopoietic stem cell proliferation. Nature 344:442, 1990
7. Broxmeyer HE, Sherry B, Lu L, Cooper S, Oh K-O, Tekamp-Olson P, Kwon BS, Cerami A: Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells. Blood 76:1110, 1990
8. Neote K, DiGregorio D, Mak JY, Horuk R, Schall TJ: Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 72:415, 1993
9. Charo I, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR: Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci USA 91:2752, 1994
10. Kitaura M, Nakajima T, Imai T, Harada S, Combadiere C, Tiffany HL, Murphy PM, Yoshie O: Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J Biol Chem 271:7725, 1996
11. Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie O: The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J Biol Chem 272:15036, 1997
12. Combadiere C, Ahuja SK, Tiffany HL, Murphy PM: Cloning and functional expression of CC CDR5, a human monocyte CC chemokine receptor selective for MIP-Ia, MIP-1α, and RANTES. J Leukoc Biol 60:147, 1996
13. Baba M, Imai T, Nishimura M, Kakizaki M, Takagi S, Hieshima K, Nomiyama H, Yoshie O: Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC. J Biol Chem 272:14893, 1997
14. Yoshida R, Imai T, Hieshima K, Kusuda J, Baba M, Kitaura M, Nishimura M, Kakizaki M, Nomiyama H, Yoshie O: Molecular cloning of a novel human CC chemokine EB11-ligand chemokine that is a specific functional ligand for EB11, CCR7. J Biol Chem 272:13803, 1997
15. Tiffany HL, Lautens LL, Gao J-L, Pease J, Locati M, Combadiere C, Modi W, Bonner TJ, Murphy PM: Identification of CCR8: A human monocyte and thymus receptor for the CC chemokine I-309. J Exp Med 186:165, 1997
16. Napolitano M, Zingoni A, Bernardini G, Spinetti G, Nista A, Storlazzi CT, Rocchi M, Santoni A: Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues. J Immunol 157:2759,1996
17. Nibbs RJB, Wylie SM, Yang J, Landau NR, Graham GJ: Cloning and characterization of a novel promiscuous human β-chemokine receptor D6. J Biol Chem 272:32078, 1997
18. Orlofsky A, Berger MS, Prystowsky MB: Novel expression pattern of a new member of the MIP-1 family of cytokine-like genes. Cell Regul 2:403, 1991
19. Youn B-S, Jang IK, Broxmeycr HE, Cooper S, Jenkins NA, Gilbert DJ, Copeland NG, Elick TA, Fraser MJ Jr, Kwon BS: A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors. J Immunol 155:2661, 1995
20. Youn B-S, Zhang SM, Lee EK, Park DH, Broxmeyer HE, Murphy PM, Locati M, Pease JE, Kim KK, Antol K, Kwon BS: Molecular cloning of leukotactin-1: A novel human β-chemokine, a chemoattractant for neutrophils, monocytes and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3. J Immunol (Cutting Edge) 159:5201, 1998
21. Forssmann U, Delgado MB, Uguccioni M, Loetscher P, Garotta G, Baggiolini M: CKβ8, a novel CC chemokine that predominantly acts on monocytes. FEBS Lett 408:211, 1997
22. Berger MS, Kozak CA, Gabriel A, Prystowsky MB: The gene for C10, a member of the β-chemokine family, is located on mouse chromosome 11 and contains a novel second exon not found in other chemokines. DNA Cell Biol 12:839, 1993
23. McCall SR, Hachicha M, Levasseur S, Neote K, Schall TJ: Uncoupling of early signal transduction events from effector function in human peripheral blood neutrophils in response to recombinant macrophage inflammatory proteins-1α and -1β. J Immunol 150:4550, 1993
24. Wells TNC, Peitsch MC: The chemokine information source: Identification and characterization of novel chemokines using the World Wide Web and expressed sequence tag databases. J Leukoc Biol 61:545, 1997
25. Tashiro K, Tada H, Heilker R, Shirozu M, Nakano T, Honjo T: Signal sequence trap: A cloning strategy for secreted proteins and type I membrane proteins. Science 261:600, 1993
26. Gao J-L, Wynn TA, Chang Y, Lee EJ, Broxmeyer HE, Cooper S, Tiffany HL, Westphal H, Kwon-Chung J, Murphy PM: Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med 185:1959, 1997
27. Naruse K, Ueono M, Satoh T, Nomiyama H, Tei H, Takeda M, Ledbetter DH, Coillie E, Opdenakker G, Gunge N, Sakaki Y, Iio M, Miura R: A YAC contig of the human CC chemokine genes clustered on chromosome 17qll.2. Genomics 34:236, 1996
28. Strieter RM, Standiford TJ, Huffnagle GB, Colletti LM, Lukacs NW, Kunkel L: "The good, the bad, and the ugly." The role of chemokines in models of human disease. Immunology 156:3583, 1996
29. Broxmeyer HE, Cooper S, Hague N, Benninger L, Sams A, Cornelia K, Vadhan-Raj S, Hendrie P, Mantel C: Human chemokines: Enhancement of specific activity and effects in vitro on normal and leukemic progenitors and a factor dependent cell line and in vivo in mice. Ann Hematol 71:235, 1995
30. Patel VP, Kreider BL, Li Y, Li H, Leung K, Salcedo T, Nardelli B, Pippalla V, Gentz S, Thotakura R, Parmelee D, Gentz R, Garotta G: Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors. J Exp Med 185:1163, 1997