Impacts of glutathione peroxidase-1 knockout on the protection by injected selenium against the pro-oxidant-induced liver aponecrosis and signaling in selenium-deficient mice

Free Radical Biology and Medicine

Volumn 34, Issue 7, 2003, Pages 918-927

  Cheng, Wen Hsing ^a   Quimby, Fred W ^b   Lei, Xin Gen ^a  

^a Department of Obstetrics Gynecology   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Apoptosis; Caspase 3; DNA fragmentation; Free radicals; GADD45; GPX1; Microarray; Necrosis; Selenium

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; GLUTATHIONE PEROXIDASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; MYC PROTEIN; OXIDIZING AGENT; PARAQUAT; PROTEIN BAX; PROTEIN BCL W; PROTEIN BCL XS; PROTEIN MDM2; SELENIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; LIVER NECROSIS; LIVER TOXICITY; MORTALITY; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SELENIUM DEFICIENCY; SIGNAL TRANSDUCTION; UPREGULATION;

RODENTIA;

EID: 0037376349     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(03)00021-2     Document Type: Article

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