Overexpression of cellular glutathione peroxidase does not affect expression of plasma glutathione peroxidase or phospholipid hydroperoxide glutathione peroxidase in mice offered diets adequate or deficient in selenium

Journal of Nutrition

Volumn 127, Issue 5, 1997, Pages 675-680

  Cheng, Wen Hsing ^a   Ho, Ye Shih ^b   Ross, Deborah A ^a   Han, Yanning ^a   Combs Jr , Gerald F ^a   Lei, Xin Gen ^a  

^a Department of Obstetrics Gynecology   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

dietary selenium; glutathione peroxidase; lipid peroxidation; overexpression; transgenic mice

Indexed keywords

GLUTATHIONE PEROXIDASE; HYDROPEROXIDE; SELENIUM;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIET; GENE EXPRESSION; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS;

EID: 0030968691     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/127.5.675     Document Type: Article

References (37)

1. Bermano, G., Nicol, F., Dyer, J. A., Sunde, R. A., Beckett, G. J., Arthur, J. R. & Hesketh, J. E. (1995) Tissue-specific regulation of selenoenyzme gene expression during selenium deficiency in rats. Biochem. J. 311: 425-430.
2. Berry, M. J., Banu, L. & Larsen, P. R. (1991) Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature (Lond.) 349: 438-440.
3. Burk, R. F. (1991) Molecular biology of selenium with implications for its metabolism. FASEB J. 5: 2274-2279.
4. Burk, R. F., Lawrence, R. A. & Lane, J. M. (1980) Liver necrosis and lipid peroxidation in the rat as the result of paraquat and diquat administration. J. Clin. Invest. 65: 1024-1031.
5. Chambers, I, Frampton, J., Goldfarb, P., Affara, N., McBain, W. & Harrison, P. R. (1986) The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the "termination" codon, TGA. EMBO J. 5: 1221-1227.
6. Christensen, M. J., Cammack, P. M. & Wray, C. D. (1995) Tissue specificity of selenoprotein gene expression in rats. J. Nutr. Biochem. 6: 367-372.
7. Chu, F.-F., Doroshow, J. H. & Esworthy, R. S. (1993) Expression, characterization, and tissue distributions of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI. J. Biol. Chem. 268: 2571-2576.
8. Cowan, D. B., Weisel, R. D., Williams, W. G. & Mickle, D. A. (1993) Identification of oxygen responsive elements in the 5′-flanking region of the human glutathione peroxidase gene. J. Biol. Chem. 268: 26904-26910.
9. Geiger, P. G., Lin, F. & Girotti, A. W. (1993) Selenoperoxidase-mediated cytoprotection against the damaging effects of tert-butyl hydroperoxide on leukemia cells. Free Radical Biol. Med. 14: 251-266.
10. Habig, W. H., Pabst, M. J. & Jakoby, W. B. (1974) Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249: 7130-7139.
11. Hawker, F. H., Ward, H. E., Stewart, P. M., Wynne, L. A. & Snitch, P. J. (1993) Selenium deficiency augments the pulmonary toxic effects of oxygen exposure in the rat. Eur. Respir. J. 6: 1317-1323.
12. Hill, K. E., Burk, R. F. & Lane, J. M. (1987) Effect of selenium depletion and repletion on plasma glutathione and glutathione-dependent enzymes in the rat. J. Nutr. 117: 99-104.
13. Ho, Y.-S., Howard, A. J. & Crapo, J. D. (1988) Nucleotide sequence of a rat glutathione peroxidase cDNA. Nucleic Acids Res. 16: 5207.
14. Ho, Y.-S., Oberley, T. D. & Gargano, M. (1995) Increased pulmonary glutathione peroxidase activity provides no protection to mice exposed to hyperoxia. Am. J. Respir. Crit. Care Med. 151: 649 (abs.).
15. Hoekstra, W. G. (1975) Biochemical function of selenium and its relation to vitamin E. Fed. Proc. 34: 2083-2089.
16. Hogan, B. Costantini, F. & Lacy, E. (1986) Manipulating the Mouse Embryo, Cold Spring Harbor, Cold Spring Harbor, NY.
17. Karimpour, I., Cutler, M., Shih, D., Smith, J. & Kleene, K. C. (1992) Sequence of the gene encoding the mitochondrial capsule selenoprotein of mouse sperm: identification of three in-phase TGA selenocysteine codons. DMA Cell Biol. 11: 693-699.
18. Kelner, M. J., Bagnell, R. D., Uglik, S. F., Montoya, M. A. & Mullenbach, G. T. (1995) Heterologous expression of selenium-dependent glutathione peroxidase affords cellular resistance to paraquat. Arch. Biochem. Biophys. 323: 40-46.
19. Knight, S.A.B. & Sunde, R. A. (1987) The effect of progressive selenium deficiency on anti-glutathione peroxidase antibody reactive protein in rat liver. J. Nutr. 117: 732-738.
20. Lee, H. S. & Csallany, A. S. (1994) The influence of vitamin E and selenium on lipid peroxidation and aldehyde dehydrogenase activity in rat liver and tissue. Lipids 29: 345-350.
21. Lei, X. G., Evenson, J. K., Patrick, D. & Sunde, R. A. (1995a) Overexpression of phospholipid hydroperoxide glutathione peroxidase in FL5.12 cells partially protects against Azo-initiated peroxidation. FASEB J. 9: A158 (abs.).
22. Lei, X. G., Evenson, J. K., Thompson, K. T. & Sunde, R. A. (1995b) Glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase are differentially regulated by dietary selenium. J. Nutr. 125: 1438-1446.
23. Levander, O. A. (1991) Scientific rationale for the 1989 recommended dietary allowance for selenium. J. Am. Diet. Assoc. 91: 1572-1576.
24. Lowry, O. H., Rosebrough, N. J., Fair, A. L. & Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.
25. Mercurio, S. D. & Combs, G. F., Jr. (1986) Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick. Biochem. Pharmcol. 35: 4505-4509.
26. Mirault, M.-E., Tremblay, A., Beaudoin, N. & Tremblay, M. (1991) Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants. J. Biol. Chem. 266: 20752-20760.
27. Mirochnitchenko, O., Palnitkar, U., Philbert, M.&Inouye, M. (1995) Thermosensitive phenotype of transgenic mice overproducing human glutathione peroxidases. Proc. Natl. Acad. Sci. U.S.A. 92: 8120-8124.
28. Moriarty, P. M., Picciano, M. F., Beard, J. L. & Reddy, C. C. (1995) Classical selenium-dependent glutathione peroxidase expression is decreased secondary to iron deficiency in rats. J. Nutr. 125: 293-301.
29. Olson, O. E., Palmer, I. S. & Cary, E. E. (1975) Modification of the official fluorometric method for Se in plants. J. Assoc. Off. Anal. Chem. 58: 117.
30. Rice-Evans, C. A., Diplock, A. T. & Symons, M.C.R. (1991) Techniques in Free Radical Research, pp. 125-184. Elsevier, Amsterdam, The Netherlands.
31. Rotruck, J. T., Pope, A. L., Ganther, H. E., Swanson, A. B., Hafeman, D. G. & Hoekstra, W. G. (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science (Washington, DC) 179: 588-590.
32. Sunde, R. A. (1994) Intracellular glutathione peroxidases-structures, regulation, and functions. In: Selenium in Biology and Human Health (Burk, R. F., ed.), pp. 45-77. Springer-Verlag, New York, NY.
33. Takahashi, K. & Cohen, H. J. (1986) Selenium-dependent glutathione peroxidase protein and activity: immunological investigations on cellular and plasma enzymes. Blood 68: 640-645.
34. Ursini, F., Maiorino, M. & Gregolin, C. (1985) The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. Biochim. Biophys. Acta 839: 62-70.
35. Vendeland, S. C., Beilstein, M. A., Yeh, J.-Y., Ream, W. & Whanger, P. D. (1995) Rat skeletal muscle selenoprotein W: cDNA clone and mRNA modulation by dietary selenium. Proc. Natl. Acad. Sci. U.S.A. 92: 8749-8753.
36. Weitzel, F., Ursini, F. & Wendel, A. (1990) Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion. Biochim. Biophys. Acta 1036: 88-94.
37. Yang, J.-G., Morrison-Plummer, J. & Burk, R. F. (1987) Purification and quantitation of a rat plasma selenoprotein distinct from glutathione peroxidase using monoclonal antibodies. J. Biol. Chem. 262: 13372-13375.