The levels of MDM2 protein are decreased by a proteasome-mediated proteolysis prior to caspase-3-dependent pRb and PARP cleavages

Journal of Korean Medical Science

Volumn 16, Issue 2, 2001, Pages 135-139

  Cho, Jae We ^a   Park, Jong Chun ^a   Lee, Je Chul ^a   Kwon, Taeg Kyu ^b   Park, Jong Wook ^b   Baek, Won Ki ^b   Suh, Seong Il ^b   Suh, Min Ho ^b  

^a Seonam University   (South Korea)

^b Keimyung University   (South Korea)

Author keywords

Apoptosis; HL 60 Cells; Ubiquitin

Indexed keywords

ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; CYSTEINE PROTEINASE; ETOPOSIDE; MDM2 PROTEIN, HUMAN; MULTIENZYME COMPLEX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEASOME; PROTEIN MDM2; RETINOBLASTOMA PROTEIN;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; DOWN REGULATION; DRUG EFFECT; HUMAN; METABOLISM; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASES; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; ETOPOSIDE; HL-60 CELLS; HUMANS; MULTIENZYME COMPLEXES; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RETINOBLASTOMA PROTEIN;

EID: 0035315902     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2001.16.2.135     Document Type: Article

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