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Volumn 7, Issue 1, 2003, Pages 243-259

Development of a hepatitis C virus vaccine

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; HEPATITIS VACCINE; LIVE VACCINE; PEPTIDE DERIVATIVE;

EID: 0037300153     PISSN: 10893261     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1089-3261(02)00067-3     Document Type: Review
Times cited : (37)

References (63)
  • 1
    • 0028147612 scopus 로고
    • Vaccination of chimpanzees against infection by the hepatitis C virus
    • Choo QL, Kuo G, Ralston R, et al. Vaccination of chimpanzees against infection by the hepatitis C virus. Proc Natl Acad Sci U S A 1994;91:1294-8.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 1294-1298
    • Choo, Q.L.1    Kuo, G.2    Ralston, R.3
  • 2
    • 0027434175 scopus 로고
    • The detection, transmission and outcome of hepatitis C virus infection
    • Alter MJ. The detection, transmission and outcome of hepatitis C virus infection. Infect Agents Dis 1993;2:155-66.
    • (1993) Infect Agents Dis , vol.2 , pp. 155-166
    • Alter, M.J.1
  • 3
    • 0031015971 scopus 로고    scopus 로고
    • Induction of cytotoxic T-cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus
    • Bruna-Romero O, Lasarte JJ, Wilkinson G, et al. Induction of cytotoxic T-cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus. Hepatology 1997;25:470-7.
    • (1997) Hepatology , vol.25 , pp. 470-477
    • Bruna-Romero, O.1    Lasarte, J.J.2    Wilkinson, G.3
  • 4
    • 9344219963 scopus 로고
    • Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome
    • Wentworth PA, Sette A, Celis E, et al. Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome. Int Immunol 1995;8:651-9.
    • (1995) Int Immunol , vol.8 , pp. 651-659
    • Wentworth, P.A.1    Sette, A.2    Celis, E.3
  • 5
    • 0026503695 scopus 로고
    • Immunity in hepatitis C virus infection
    • Prince AM, Brotman T, Huima D, et al. Immunity in hepatitis C virus infection. J Infect Dis 1992;165:438-43.
    • (1992) J Infect Dis , vol.165 , pp. 438-443
    • Prince, A.M.1    Brotman, T.2    Huima, D.3
  • 6
    • 0034623816 scopus 로고    scopus 로고
    • Efficient replication of HCV RNA replication in cell culture
    • Blight K, Kolykhalov AA, Rice CM. Efficient replication of HCV RNA replication in cell culture. Science 2000;290:1972-4.
    • (2000) Science , vol.290 , pp. 1972-1974
    • Blight, K.1    Kolykhalov, A.A.2    Rice, C.M.3
  • 7
    • 0031899309 scopus 로고    scopus 로고
    • Genetic complexity of the hypervariable region 1 (HVR1) of hepatitis C virus (HCV): Influence on the characteristics of the infection and responses to interferon alfa therapy in patients with chronic hepatitis C
    • Pawlotsky JM, Pellerin M, Bouvier M, et al. Genetic complexity of the hypervariable region 1 (HVR1) of hepatitis C virus (HCV): influence on the characteristics of the infection and responses to interferon alfa therapy in patients with chronic hepatitis C. J Med Virol 1998;54:256-64.
    • (1998) J Med Virol , vol.54 , pp. 256-264
    • Pawlotsky, J.M.1    Pellerin, M.2    Bouvier, M.3
  • 8
    • 0033429088 scopus 로고    scopus 로고
    • Viral heterogeneity of the hepatitis C virus
    • Simmonds P. Viral heterogeneity of the hepatitis C virus. J Hepatol 1999:31:54-60.
    • (1999) J Hepatol , vol.31 , pp. 54-60
    • Simmonds, P.1
  • 9
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alpha-2b in combination with ribavirin compared with interferon alpha-2b plus ribavirin for initial treatment of chronic hepatitis C: Results of a randomized trial
    • Manns MP, McHutchinson JG, Gordon SC, et al. Peginterferon alpha-2b in combination with ribavirin compared with interferon alpha-2b plus ribavirin for initial treatment of chronic hepatitis C: results of a randomized trial. Lancet 2001;358:958-65.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchinson, J.G.2    Gordon, S.C.3
  • 10
    • 0035856208 scopus 로고    scopus 로고
    • Primary interferon resistance and treatment response in chronic hepatitis C infection: A pilot study
    • Jessner W, Gschwantler M, Steindl-Munda P, et al. Primary interferon resistance and treatment response in chronic hepatitis C infection: a pilot study. Lancet 2001;358:1241-2.
    • (2001) Lancet , vol.358 , pp. 1241-1242
    • Jessner, W.1    Gschwantler, M.2    Steindl-Munda, P.3
  • 11
    • 0028835980 scopus 로고
    • Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA-A2 binding motif
    • Cerny A, McHutchinson JG, Pasquinelli C, et al. Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA-A2 binding motif. J Clin Invest 1995;95:521-30.
    • (1995) J Clin Invest , vol.95 , pp. 521-530
    • Cerny, A.1    McHutchinson, J.G.2    Pasquinelli, C.3
  • 12
    • 0034253331 scopus 로고    scopus 로고
    • Vigorous peripheral blood cytotoxic T cell response during the acute phase of hepatitis C virus infection
    • Cucchiarini M, Kammer AR, Grabscheid B, et al. Vigorous peripheral blood cytotoxic T cell response during the acute phase of hepatitis C virus infection. Cell Immunol 2000;203:111-23.
    • (2000) Cell Immunol , vol.203 , pp. 111-123
    • Cucchiarini, M.1    Kammer, A.R.2    Grabscheid, B.3
  • 13
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme R, Oldach D, Chang K-M, et al. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 2001;194:1395-406.
    • (2001) J Exp Med , vol.194 , pp. 1395-1406
    • Thimme, R.1    Oldach, D.2    Chang, K.-M.3
  • 14
    • 0036149967 scopus 로고    scopus 로고
    • Effect of interferon-alpha therapy on epitope-specific cytotoxic T lymphocyte responses in hepatitis C virus-infected individuals
    • Vertuani S, Bazzaro M, Gualandi G, et al. Effect of interferon-alpha therapy on epitope-specific cytotoxic T lymphocyte responses in hepatitis C virus-infected individuals. Eur J Immunol 2002;32:144-54.
    • (2002) Eur J Immunol , vol.32 , pp. 144-154
    • Vertuani, S.1    Bazzaro, M.2    Gualandi, G.3
  • 15
    • 0030790664 scopus 로고
    • Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection
    • Diepolder HM, Gerlach JT, Zachoval R, et al. Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection. J Virol 1995;71:6011-9.
    • (1995) J Virol , vol.71 , pp. 6011-6019
    • Diepolder, H.M.1    Gerlach, J.T.2    Zachoval, R.3
  • 16
    • 85088083657 scopus 로고
    • HLA class-restricted cytotoxic T lymphocytes specific for hepatitis C virus
    • Koziel M, Dudley D, Afdhal N, et al. HLA class-restricted cytotoxic T lymphocytes specific for hepatitis C virus. J Clin Invest 1995;95:521-30.
    • (1995) J Clin Invest , vol.95 , pp. 521-530
    • Koziel, M.1    Dudley, D.2    Afdhal, N.3
  • 17
    • 0029778817 scopus 로고    scopus 로고
    • Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C infection
    • Rehermann B, Chang KM, McHutchinson J, et al. Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C infection. J Clin Invest 1996;98:1432-40.
    • (1996) J Clin Invest , vol.98 , pp. 1432-1440
    • Rehermann, B.1    Chang, K.M.2    McHutchinson, J.3
  • 18
    • 0034915714 scopus 로고    scopus 로고
    • Hepatitis C virus-like particles induce virus-specific humoral and cellular immune response in mice
    • Lechmann M, Murata K, Satoi J, et al. Hepatitis C virus-like particles induce virus-specific humoral and cellular immune response in mice. Hepatology 2001;34:417-23.
    • (2001) Hepatology , vol.34 , pp. 417-423
    • Lechmann, M.1    Murata, K.2    Satoi, J.3
  • 19
    • 0033829854 scopus 로고    scopus 로고
    • CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained
    • Lechner F, Gruener NH, Urbani S, et al. CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained. Eur J Immunol 2000;30:2479-87.
    • (2000) Eur J Immunol , vol.30 , pp. 2479-2487
    • Lechner, F.1    Gruener, N.H.2    Urbani, S.3
  • 20
    • 18244397979 scopus 로고    scopus 로고
    • The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes
    • Erickson AL, Kimura Y, Igarashi S, et al. The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. Immunity 2001;15:883-95.
    • (2001) Immunity , vol.15 , pp. 883-895
    • Erickson, A.L.1    Kimura, Y.2    Igarashi, S.3
  • 21
    • 0035121503 scopus 로고    scopus 로고
    • Chronic infection by hepatitis C virus is associated with impairment of allostimulatory function of monocyte-derived dendritic cells and stringent selection of viral variants
    • Bain C, Fatmi A, Zoulim F, et al. Chronic infection by hepatitis C virus is associated with impairment of allostimulatory function of monocyte-derived dendritic cells and stringent selection of viral variants. Gastroenterology 2001;120:512-24.
    • (2001) Gastroenterology , vol.120 , pp. 512-524
    • Bain, C.1    Fatmi, A.2    Zoulim, F.3
  • 22
    • 0033136306 scopus 로고    scopus 로고
    • Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals
    • Kanto T, Hayashi N, Takehara T, et al. Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J Immunol 1999;162:5584-91.
    • (1999) J Immunol , vol.162 , pp. 5584-5591
    • Kanto, T.1    Hayashi, N.2    Takehara, T.3
  • 23
    • 0028087985 scopus 로고
    • Prevention of hepatitis C virus infection in chimpanzees after Ab-mediated in vitro neutralization
    • Farci P, Alter HJ, Wong DC, et al. Prevention of hepatitis C virus infection in chimpanzees after Ab-mediated in vitro neutralization. Proc Natl Acad Sci U S A 1994;91:7792-6.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7792-7796
    • Farci, P.1    Alter, H.J.2    Wong, D.C.3
  • 24
    • 0030042116 scopus 로고    scopus 로고
    • Hepatitis C virus: Detection of intracellular virus particles by electron microscopy
    • Shimizu YK, Feinstone SM, Kohara M, et al. Hepatitis C virus: detection of intracellular virus particles by electron microscopy. Hepatology 1996;23:205-9.
    • (1996) Hepatology , vol.23 , pp. 205-209
    • Shimizu, Y.K.1    Feinstone, S.M.2    Kohara, M.3
  • 26
    • 0033119925 scopus 로고    scopus 로고
    • Analysis of a successful immune response against hepatitis C virus
    • Cooper S, Erickson AL, Adams EJ, et al. Analysis of a successful immune response against hepatitis C virus. Immunity 1999;10:439-49.
    • (1999) Immunity , vol.10 , pp. 439-449
    • Cooper, S.1    Erickson, A.L.2    Adams, E.J.3
  • 27
    • 0034030136 scopus 로고    scopus 로고
    • Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C
    • Takaki A, Wiese M, Maertens G, et al. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. Nat Med 2000;6:578-82.
    • (2000) Nat Med , vol.6 , pp. 578-582
    • Takaki, A.1    Wiese, M.2    Maertens, G.3
  • 28
    • 0028962927 scopus 로고
    • Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules
    • Battegay M, Fikes J, Di Bisceglie AM, et al. Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules. J Virol 1995;69:2462-70.
    • (1995) J Virol , vol.69 , pp. 2462-2470
    • Battegay, M.1    Fikes, J.2    Di Bisceglie, A.M.3
  • 29
    • 0032940425 scopus 로고    scopus 로고
    • Helper T cell determinant peptide contributes to induction of cellular immune responses by peptide vaccines against hepatitis C virus
    • Hiranuma K, Tamaki S, Nishimura Y, et al. Helper T cell determinant peptide contributes to induction of cellular immune responses by peptide vaccines against hepatitis C virus. J Gen Virol 1999;80:187-93.
    • (1999) J Gen Virol , vol.80 , pp. 187-193
    • Hiranuma, K.1    Tamaki, S.2    Nishimura, Y.3
  • 30
    • 0028912912 scopus 로고
    • CTL response of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1
    • Shirai M, Arici T, Nishioka M, et al. CTL response of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1. J Immunol 1995;154:2733-42.
    • (1995) J Immunol , vol.154 , pp. 2733-2742
    • Shirai, M.1    Arici, T.2    Nishioka, M.3
  • 31
    • 0032531164 scopus 로고    scopus 로고
    • Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions
    • Sarobe P, Pendleton CD, Akatsuka T, et al. Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions. J Clin Invest 1998;102:1239-48.
    • (1998) J Clin Invest , vol.102 , pp. 1239-1248
    • Sarobe, P.1    Pendleton, C.D.2    Akatsuka, T.3
  • 32
    • 0343484313 scopus 로고    scopus 로고
    • Th1 but not Th0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides
    • Lopez-Diaz de Cerio A, Casares N, Lasarte JJ, et al. Th1 but not Th0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides. Int Immunol 1999;11:2025-33.
    • (1999) Int Immunol , vol.11 , pp. 2025-2033
    • Lopez-Diaz de Cerio, A.1    Casares, N.2    Lasarte, J.J.3
  • 33
    • 0029947995 scopus 로고    scopus 로고
    • Selection of antigenic and immunogenic mimics of hepatitis C virus using sera from patients
    • Prezzi C, Nuzzo M, Meola A, et al. Selection of antigenic and immunogenic mimics of hepatitis C virus using sera from patients. J Imunol 1996;156:4504-13.
    • (1996) J Imunol , vol.156 , pp. 4504-4513
    • Prezzi, C.1    Nuzzo, M.2    Meola, A.3
  • 34
    • 0032125798 scopus 로고    scopus 로고
    • Towards a solution for hepatitis C virus hypervariability: Mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants
    • Puntoriero G, Meola A, Lahm A, et al. Towards a solution for hepatitis C virus hypervariability: mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants. EMBO J 1998;17:3521-33.
    • (1998) EMBO J , vol.17 , pp. 3521-3533
    • Puntoriero, G.1    Meola, A.2    Lahm, A.3
  • 35
    • 17544368390 scopus 로고    scopus 로고
    • Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: An endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA6based vaccine candidates
    • Heile JM, Fong YL, Rosa D, et al. Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA6based vaccine candidates. J Virol 2000;74:6885-92.
    • (2000) J Virol , vol.74 , pp. 6885-6892
    • Heile, J.M.1    Fong, Y.L.2    Rosa, D.3
  • 36
    • 4244042223 scopus 로고    scopus 로고
    • A quantitative test to estimate neutralizing antibodies to hepatitis C virus: Cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells
    • Rosa D, Campagnoli S, Moretto C, et al. A quantitative test to estimate neutralizing antibodies to hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells. Proc Natl Acad Sci U S A 1996;93:1759-63.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1759-1763
    • Rosa, D.1    Campagnoli, S.2    Moretto, C.3
  • 37
    • 0032737567 scopus 로고    scopus 로고
    • Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate
    • Baumert TF, Vergalla J, Satoi J, et al. Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate. Gastroenterology 1999;117:1397-407.
    • (1999) Gastroenterology , vol.117 , pp. 1397-1407
    • Baumert, T.F.1    Vergalla, J.2    Satoi, J.3
  • 38
    • 0035852316 scopus 로고    scopus 로고
    • Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells treated with an anthrax toxin fusion protein
    • Moriya O, Matsui M, Osorio M, et al. Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells treated with an anthrax toxin fusion protein. Vaccine 2002;20:789-96.
    • (2002) Vaccine , vol.20 , pp. 789-796
    • Moriya, O.1    Matsui, M.2    Osorio, M.3
  • 39
    • 0035284757 scopus 로고    scopus 로고
    • Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by nonclassical ISCOM vaccine
    • Polakos NK, Drane D, Cox J, et al. Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by nonclassical ISCOM vaccine. J Immunol 2001;166:3589-98.
    • (2001) J Immunol , vol.166 , pp. 3589-3598
    • Polakos, N.K.1    Drane, D.2    Cox, J.3
  • 40
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from blood-borne non-A, non-B viral hepatitis genome
    • Choo QL, Kuo G, Weiner AJ, et al. Isolation of a cDNA clone derived from blood-borne non-A, non-B viral hepatitis genome. Science 1989;244:359-62.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3
  • 41
    • 0034886079 scopus 로고    scopus 로고
    • DNA vaccines for hepatitis C virus
    • Brinster C, Inchauspé G. DNA vaccines for hepatitis C virus. Intervirology 2001a;144:143-53.
    • (2001) Intervirology , vol.144 , pp. 143-153
    • Brinster, C.1    Inchauspé, G.2
  • 42
    • 0031066827 scopus 로고    scopus 로고
    • Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids
    • Geissler M, Gesien A, Tokushige K, et al. Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids. J Immunol 1997;158:1231-7.
    • (1997) J Immunol , vol.158 , pp. 1231-1237
    • Geissler, M.1    Gesien, A.2    Tokushige, K.3
  • 43
    • 85120146975 scopus 로고    scopus 로고
    • HLA-A2.1 transgenic mouse model: Potential utility for development of an HCV vaccine
    • Renard N, Boucreux D, Lemonnier F, et al. HLA-A2.1 transgenic mouse model: potential utility for development of an HCV vaccine. J Hepatol 2000;32:362-4.
    • (2000) J Hepatol , vol.32 , pp. 362-364
    • Renard, N.1    Boucreux, D.2    Lemonnier, F.3
  • 44
    • 0029971032 scopus 로고    scopus 로고
    • Expression and immune response to hepatitis C virus core DNA-based vaccine constructs
    • Tokushige K, Wakita T, Pachuk G, et al. Expression and immune response to hepatitis C virus core DNA-based vaccine constructs. Hepatology 1996;24:14-20.
    • (1996) Hepatology , vol.24 , pp. 14-20
    • Tokushige, K.1    Wakita, T.2    Pachuk, G.3
  • 45
    • 0034715558 scopus 로고    scopus 로고
    • Use of conventional or replicating nucleic acid-based vaccines and recombinant semliki forest virus-derived particles for the induction of immune responses against hepatitis C virus core and E2 antigens
    • Vidalin O, Fournillier A, Renard N, et al. Use of conventional or replicating nucleic acid-based vaccines and recombinant semliki forest virus-derived particles for the induction of immune responses against hepatitis C virus core and E2 antigens. Virology 2000;276:259-70.
    • (2000) Virology , vol.276 , pp. 259-270
    • Vidalin, O.1    Fournillier, A.2    Renard, N.3
  • 46
    • 0036166630 scopus 로고    scopus 로고
    • Hepatitis C virus non-structural protein 3-specific cellular immune responses following single or combined immunization with DNA or recombinant semliki forest virus particles
    • Brinster C, Chen M, Boucreux D, et al. Hepatitis C virus non-structural protein 3-specific cellular immune responses following single or combined immunization with DNA or recombinant semliki forest virus particles. J Gen Virol 2002;83:369-81.
    • (2002) J Gen Virol , vol.83 , pp. 369-381
    • Brinster, C.1    Chen, M.2    Boucreux, D.3
  • 47
    • 0030817934 scopus 로고    scopus 로고
    • Immunization with plasmid DNA encoding hepatitis C virus envelope E2 antigenic domains induces antibodies whose immune reactivity is linked to the injection mode
    • Nakano I, Maertens G, Major ME, et al. Immunization with plasmid DNA encoding hepatitis C virus envelope E2 antigenic domains induces antibodies whose immune reactivity is linked to the injection mode. J Virol 1997;71:7101-9.
    • (1997) J Virol , vol.71 , pp. 7101-7109
    • Nakano, I.1    Maertens, G.2    Major, M.E.3
  • 48
    • 0030914741 scopus 로고    scopus 로고
    • Plasmid DNA-based immunization for hepatitis C virus structural proteins: Immune responses in mice
    • Saito T, Sherman GJ, Kurokohchi K, et al. Plasmid DNA-based immunization for hepatitis C virus structural proteins: immune responses in mice. Gastroenterology 1997;112:1321-30.
    • (1997) Gastroenterology , vol.112 , pp. 1321-1330
    • Saito, T.1    Sherman, G.J.2    Kurokohchi, K.3
  • 49
    • 0033537880 scopus 로고    scopus 로고
    • DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface
    • Forns X, Emerson SU, Tobin GJ, et al. DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface. Vaccine 1999;17:1992-2002.
    • (1999) Vaccine , vol.17 , pp. 1992-2002
    • Forns, X.1    Emerson, S.U.2    Tobin, G.J.3
  • 50
    • 0031664801 scopus 로고    scopus 로고
    • Optimal induction of hepatitis C virus envelope-specific immunity by bicistronic plasmid DNA inoculation with the granulocyte-macrophage colony-stimulating factor gene
    • Lee SW, Cho JH, Sung YC. Optimal induction of hepatitis C virus envelope-specific immunity by bicistronic plasmid DNA inoculation with the granulocyte-macrophage colony-stimulating factor gene. J Virol 1998;72:8430-6.
    • (1998) J Virol , vol.72 , pp. 8430-8436
    • Lee, S.W.1    Cho, J.H.2    Sung, Y.C.3
  • 51
    • 0032866177 scopus 로고    scopus 로고
    • Expression of noncovalent hepatitis C virus envelope E1-E2 complexes is not required for the induction of antibodies with neutralizing properties following DNA immunization
    • Fournillier A, Karaiyannis P, Vidalin O, et al. Expression of noncovalent hepatitis C virus envelope E1-E2 complexes is not required for the induction of antibodies with neutralizing properties following DNA immunization. J Virol 1999;73:7497-504.
    • (1999) J Virol , vol.73 , pp. 7497-7504
    • Fournillier, A.1    Karaiyannis, P.2    Vidalin, O.3
  • 52
    • 0025770126 scopus 로고
    • Absence of asparagines-linked oligosaccharides from glycoprotein D of herpes simplex virus type 1 results in a structurally altered but biologically active protein
    • Sodora DL, Cohen GH, Muggeridge MI, et al. Absence of asparagines-linked oligosaccharides from glycoprotein D of herpes simplex virus type 1 results in a structurally altered but biologically active protein. J Virol 1991;65:4424-31.
    • (1991) J Virol , vol.65 , pp. 4424-4431
    • Sodora, D.L.1    Cohen, G.H.2    Muggeridge, M.I.3
  • 53
    • 0035202613 scopus 로고    scopus 로고
    • Induction of hepatitis C virus E1 envelope protein-specific immune response can be enhanced by mutation of the N-glycosylation sites
    • Fournillier A, Wychowsky C, Boucreux D, et al. Induction of hepatitis C virus E1 envelope protein-specific immune response can be enhanced by mutation of the N-glycosylation sites. J Virol 2001;75:12088-97.
    • (2001) J Virol , vol.75 , pp. 12088-12097
    • Fournillier, A.1    Wychowsky, C.2    Boucreux, D.3
  • 54
    • 0035202920 scopus 로고    scopus 로고
    • Genetic immunization of wild type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins
    • Satoi J, Murata K, Lechmann M, et al. Genetic immunization of wild type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins. J Virol 2001;75:12121-7.
    • (2001) J Virol , vol.75 , pp. 12121-12127
    • Satoi, J.1    Murata, K.2    Lechmann, M.3
  • 55
    • 0032212215 scopus 로고    scopus 로고
    • Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model
    • Encke J, Zu PJ, Geissler M, et al. Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model. J Immunol 1998;161:4917-23.
    • (1998) J Immunol , vol.161 , pp. 4917-4923
    • Encke, J.1    Zu, P.J.2    Geissler, M.3
  • 56
    • 0344097496 scopus 로고    scopus 로고
    • Enhanced cellular immunity tohepatitis C virus nonstructural proteins by codelivery of granulocyte macrophage-colony stimulating factor gene in intramuscular DNA immunization
    • Cho JH, Lee SW, Sung YC. Enhanced cellular immunity tohepatitis C virus nonstructural proteins by codelivery of granulocyte macrophage-colony stimulating factor gene in intramuscular DNA immunization. Vaccine 1999;17:1136-44.
    • (1999) Vaccine , vol.17 , pp. 1136-1144
    • Cho, J.H.1    Lee, S.W.2    Sung, Y.C.3
  • 57
    • 0030062317 scopus 로고    scopus 로고
    • Induction of antibodies against structural proteins of hepatitis C virus in mice using recombinant adenovirus
    • Makimura M, Miyake S, Akino N, et al. Induction of antibodies against structural proteins of hepatitis C virus in mice using recombinant adenovirus. Vaccine 1996;14:28-34.
    • (1996) Vaccine , vol.14 , pp. 28-34
    • Makimura, M.1    Miyake, S.2    Akino, N.3
  • 58
    • 0034766336 scopus 로고    scopus 로고
    • Oral immunization with HCV-NS3 transformed Salmonella: Induction of HCV-specific CTL in a trangenic mouse model
    • Wedemeyer H, Gagneten S, Davis A, et al. Oral immunization with HCV-NS3 transformed Salmonella: induction of HCV-specific CTL in a trangenic mouse model. Gastroenterology 2001;121:1158-66.
    • (2001) Gastroenterology , vol.121 , pp. 1158-1166
    • Wedemeyer, H.1    Gagneten, S.2    Davis, A.3
  • 59
    • 0033914296 scopus 로고    scopus 로고
    • DNA prime-Canarypox boost with polycistronic hepatitis C virus (HCV) genes generates potent immune responses to HCV structural and nonstructural proteins
    • Pancholi P, Liu Q, Tricoche N, et al. DNA prime-Canarypox boost with polycistronic hepatitis C virus (HCV) genes generates potent immune responses to HCV structural and nonstructural proteins. J Infect Dis 2000;182:18-27.
    • (2000) J Infect Dis , vol.182 , pp. 18-27
    • Pancholi, P.1    Liu, Q.2    Tricoche, N.3
  • 60
    • 0032785706 scopus 로고    scopus 로고
    • Targeting of hepatitis C virus core protein for MHC I or MHC II presentation does not enhance induction of immune responses to DNA vaccination
    • Vidalin O, Tanaka E, Spengler U, et al. Targeting of hepatitis C virus core protein for MHC I or MHC II presentation does not enhance induction of immune responses to DNA vaccination. DNA Cell Biol 1999;18:611-21.
    • (1999) DNA Cell Biol , vol.18 , pp. 611-621
    • Vidalin, O.1    Tanaka, E.2    Spengler, U.3
  • 61
    • 0036891882 scopus 로고    scopus 로고
    • Comparative vaccine studies in HLA-A2.1-transgenic mice reveal a clustered organization of epitopes presented in Hepatitic C virus natural infection
    • Himoudi N, Abraham JD, Fournillier A, et al. Comparative vaccine studies in HLA-A2.1-transgenic mice reveal a clustered organization of epitopes presented in Hepatitic C virus natural infection. J Virol 2002;76(24):12735-46.
    • (2002) J Virol , vol.76 , Issue.24 , pp. 12735-12746
    • Himoudi, N.1    Abraham, J.D.2    Fournillier, A.3


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