Towards a solution for hepatitis C virus hypervariability: Mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants

EMBO Journal

Volumn 17, Issue 13, 1998, Pages 3521-3533

  Puntoriero, Giulia ^a   Meola, Annalisa ^a   Lahm, Armin ^a   Zucchelli, Silvia ^a   Ercole, Bruno Bruni ^a   Tafi, Rosalba ^a   Pezzanera, Monica ^a   Mondelli, Mario U ^b   Cortese, Riccardo ^a   Tramontano, Anna ^a   Galfre', Giovanni ^a   Nicosia, Alfredo ^a  

^a IRBM   (Italy)

^b NONE

Author keywords

Hepatitis C virus; Hypervariable region 1; Phage library

Indexed keywords

HEPATITIS C ANTIBODY; HEPATITIS C VACCINE; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; CROSS REACTION; HEPATITIS C VIRUS; HUMAN; IMMUNE RESPONSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; VACCINE PRODUCTION; VIRUS ISOLATION; VIRUS MORPHOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENIC VARIATION; BACTERIOPHAGE M13; CLONING, MOLECULAR; CROSS REACTIONS; EPITOPES, B-LYMPHOCYTE; FEMALE; GENE LIBRARY; GENETIC VECTORS; HEPACIVIRUS; HEPATITIS C ANTIBODIES; HEPATITIS C, CHRONIC; HUMANS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; STRUCTURE-ACTIVITY RELATIONSHIP; VARIATION (GENETICS); VIRAL ENVELOPE PROTEINS;

EID: 0032125798     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.13.3521     Document Type: Article

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