The use of non-tumor data in cancer risk assessment: Reflections on butadiene, vinyl chloride, and benzene

Regulatory Toxicology and Pharmacology

Volumn 37, Issue 1, 2003, Pages 105-132

  Albertini, Richard ^a   Clewell, Harvey ^b   Himmelstein, Matthew W ^c   Morinello, Eric ^d,j   Olin, Stephen ^e   Preston, Julian ^f   Scarano, Louis ^e,k   Smith, Martyn T ^g   Swenberg, James ^d   Tice, Raymond ^h   Travis, Curtis ⁱ  

^a UNIVERSITY OF VERMONT   (United States)

^b ENVIRON INTERNATIONAL CORPORATION   (United States)

^c DUPONT COMPANY   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e ILSI Risk Science Institute   (United States)

^f U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h INTEGRATED LABORATORY SYSTEMS   (United States)

ⁱ Quest Technologies   (United States)

^j SOUTHERN RESEARCH INSTITUTE   (United States)

^k U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

more..

Author keywords

1,3 Butadiene; Benzene; Biomarkers; Cancer; Principles; Risk assessment; Vinyl chloride

Indexed keywords

1,3 BUTADIENE; BENZENE; BIOLOGICAL MARKER; DNA; GLYCOPHORIN A; VINYL CHLORIDE;

ANGIOSARCOMA; BIOASSAY; CANCER MODEL; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL CULTURE; CHEMICAL CARCINOGENESIS; CHO CELL; CYTOTOXICITY; DNA ADDUCT; DNA DAMAGE; DOSE RESPONSE; DOSIMETRY; EXPERIMENTAL MODEL; GENE DELETION; GENE LOCUS; GENE MUTATION; GENOTOXICITY; GERM CELL; HETEROZYGOSITY LOSS; HUMAN; HYPOTHESIS; LEUKEMOGENESIS; MICRONUCLEUS; MUTAGENIC ACTIVITY; MUTAGENICITY; MUTATIONAL ANALYSIS; NONHUMAN; NUMERICAL CHROMOSOME ABERRATION; PRECANCER; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; STRUCTURAL CHROMOSOME ABERRATION; TARGET ORGAN; TOXICOKINETICS;

ANIMALIA;

EID: 0037298668     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0273-2300(02)00019-3     Document Type: Review

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