Detection of 1,N2-propanodeoxyguanosine adducts as potential endogenous DNA lesions in rodent and human tissues

Cancer Research

Volumn 56, Issue 3, 1996, Pages 452-456

  Nath, Raghu G ^a   Ocando, Joseph E ^a   Chung, Fung Lung ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,N2 PROPANODEOXYGUANOSINE DERIVATIVE; ACROLEIN; CROTONALDEHYDE; DEOXYGUANOSINE DERIVATIVE; DNA; GUANINE; PHOSPHATE; PHOSPHORUS 32; UNCLASSIFIED DRUG; 1,N(2) PROPANODEOXYGUANOSINE; 1,N(2)-PROPANODEOXYGUANOSINE; 2-BUTENAL; ALDEHYDE; CARCINOGEN; DEOXYGUANOSINE; DRUG DERIVATIVE; PHOSPHORUS;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; COLON; DNA ADDUCT; FEMALE; HUMAN; HUMAN CELL; KIDNEY PARENCHYMA; LEUKOCYTE; LUNG PARENCHYMA; MALE; MAMMARY GLAND; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SKIN; A J MOUSE; ANIMAL; DNA DAMAGE; DRUG EFFECT; FISCHER 344 RAT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MIDDLE AGED;

ACROLEIN; ADULT; ALDEHYDES; ANIMALS; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; DNA ADDUCTS; DNA DAMAGE; FEMALE; HUMANS; MALE; MICE; MICE, INBRED A; MIDDLE AGED; PHOSPHORUS RADIOISOTOPES; RATS; RATS, INBRED F344;

EID: 0029664516     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Marnett, L J., and Burcham, P C. Endogenous DNA adducts: potential and paradox. Chem Res. Toxicol., 6 771-785, 1993.
2. Shigenaga, M K., Hagen, T. M., and Ames, B. N. Oxidative damage and mitochondrial decay in aging Proc. Natl Acad Sci USA, 91: 10771-10778, 1994
3. Esterbauer, H , Eckl, P., and Ortner, A. Possible mutagens derived from lipids and lipid precursors. Mutat. Res., 238: 223-233, 1990.
4. Chung, F-L., Chen, H-J. C., Guttenplan, J. B., Nishikawa, A., and Hard, G. C. 2,3-Epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation. Carcinogenesis (Lond.), 14. 2073-2077, 1993.
5. 2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde. Cancer Res., 44: 990-995, 1984.
6. Sodum, R. S., and Chung, F-L. Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal. Cancer Res., 51: 137-143, 1991.
7. Winter, C. K. Segall, H. J , and Haddon, W. F. Formation of cyclic adducts of deoxyguanosine with the aldehydes trans-4-hydroxy-2-hexanal and trans-4-hydroxy-2-nonenal in vitro. Cancer Res. 46: 5682-5686, 1986.
8. Marnett, L J. DNA adducts of α,β-unsaturated aldehydes and dicarbonyl compounds. IARC Sci Publ., 125: 151-163, 1994.
9. IARC. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Vol 19, pp 479-494. Lyon. France: IARC, 1979.
10. Wynder, E L , Goodman, D. A., and Hoffmann, D. Ciliatoxic compounds in cigarette smoke. II Carboxylic acids and aldehydes. Cancer (Phila.), 18: 505-509, 1965.
11. Bauer, K., Czech, K., and Porter, A. Severe accidental acrolein intoxication at home. Wien Klin Wochenschr., 89: 243-244, 1977.
12. Feron, V J , Til, H. P., de Vrijer, F., Woutersen, R. A., Cassee, F. R., and van Bladeren, P. J. Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment. Mutat Res., 259: 363-385, 1991
13. 2-propanodeoxyguanosine adducts in DNA of rats treated with N-nitrosopyrrolidine and mice treated with crotonaldehyde. Carcinogenesis (Lond.), 10: 1291-1297, 1989.
14. 32P-postlabeling and nucleotide chromatography. Carcinogenesis (Lond.), 12: 1483-1490, 1992.
15. Foiles, P. G., Akerkar, S A., Miglietta, L M., and Chung, F-L. Formation of cyctic deoxyguanosine adducts in Chinese hamster ovary cells by acrolein and crotonaldehyde. Carcinogenesis (Lond.), 11: 2059-2061, 1990
16. Foiles, P. G., Akerkar, S A., and Chung, F-L. Application of an immunoassay for cyclic acrolein deoxyguanosine adducts to assess their formation in DNA of Salmonella typhimurium under conditions of mutation induction by acrolein. Carcinogenesis (Lond.), 10: 87-90, 1989
17. 4 hot-spot of Salmonella typhimurium his D3052 carried on an M13 vector. J. Biol Chem., 267: 22392-22400, 1992.
18. Moriya, M , Zhang, W., Johnson, F., and Grollman, A. P. Mutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells. Proc Natl. Acad Sci USA, 91: 11899-11903, 1994
19. 32P-postlabeling method for simultaneous detection and quantification of exocyclic etheno and propano adducts in DNA. Carcinogenesis (Lond.), 15: 979-984, 1994.
20. Gupta, R. C. Nonrandom binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proc. Natl Acad. Sci. USA, 81: 6943-6947, 1984.
21. Marmur, J. A. A procedure for isolation of deoxyribonucleic acid from microorganisms. J. Mol. Biol., 3: 208-218, 1961.
22. 2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans. Proc. Natl. Acad. Sci. USA, 91: 7491-7495, 1994.
23. Russo, A , Mitchell, J. B , DeGraff, W., Friedman, N., and Gamson, J. Depletion of cellular glutathione by exogenous spermine in V79 cells: implications for spermme induced hyperthermic sensitization. Cancer Res., 45: 4910-4914, 1985.
24. Zlatkis, A., Poole, C. F., Brazeli, R., Bafus, D A., and Spencer, P S. Volatile metabolites in sera of normal and diabetic patients. J. Chromatogr., 182: 137-145, 1980.
25. Preussmann, R. Occurrence and exposure to N-nitroso compounds and precursors. In: I. K. O'Neill, R. C. Von Borstel, C. T. Miller, J. Long, and H. Bartsch (eds), N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, pp. 3-15. Lyon, France: IARC, 1984.
26. Tricker, A. R., Pfundstein, B., Kalble, T., and Preussmann, R. Secondary amine precursors to nitrosamines in human saliva, gastric juice, blood, urine and feces Carcinogenesis (Lond.), 13: 563-568, 1992.
27. 32P-postlabeling. Carcinogenesis (Lond.), 16. 613-617, 1995.
28. Chaudhary, A. K., Nokubo, M., Reddy, G R., Yeola, S. N , Morrow, J. D., Blair, I. A., and Marnett, L. J. Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver. Science (Washington DC), 265. 1580-1582, 1994.