Inhalation exposure of rats and mice to 1,3-butadiene induces N6-adenine adducts of epoxybutene detected by 32P-postlabeling and HPLC

Environmental Health Perspectives

Volumn 104, Issue SUPPL. 3, 1996, Pages 655-657

  Koivisto, Pertti ^a   Adler, Ilse Dore ^b   Sorsa, Marja ^a   Peltonen, Kimmo ^a  

^a FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

1,3 butadiene; 3,4 epoxy 1 butene; 32P postlabeling; Adducts; Adenine; DNA; Guanine; HPLC; Inhalation

Indexed keywords

1,3 BUTADIENE; ADENINE; EPOXYBUTENE; GUANINE; PHOSPHORUS 32; PURINE DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ALKYLATION; ANIMAL TISSUE; CATTLE; CONFERENCE PAPER; CONTROLLED STUDY; DNA ADDUCT; DNA BINDING; DOSE RESPONSE; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID PHASE EXTRACTION; THIN LAYER CHROMATOGRAPHY; THYMUS;

ADENINE; ADMINISTRATION, INHALATION; ALKYLATION; ANIMALS; BUTADIENES; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DNA ADDUCTS; EPOXY COMPOUNDS; GUANINE; MICE; PHOSPHORUS RADIOISOTOPES; RATS;

ANIMALIA; BOS TAURUS;

EID: 0029994012     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.96104s3655     Document Type: Article

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