메뉴 건너뛰기




Volumn 52, Issue 1, 2003, Pages 18-25

CD40 ligation triggers COX-2 expression in endothelial cells: Evidence that CD40-mediated IL-6 synthesis is COX-2-dependent

Author keywords

CD154; Endothelial cells; Inflammation; Prostaglandins

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND MONOCLONAL ANTIBODY; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GAMMA INTERFERON; IBUPROFEN; INTERLEUKIN 6; ISOBUTYLMETHYLXANTHINE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTANOID;

EID: 0037285989     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110300009     Document Type: Article
Times cited : (16)

References (54)
  • 1
    • 0034078228 scopus 로고    scopus 로고
    • New insights into the role of COX-2 in inflammation
    • Gilroy D, Colville-Nash PR. New insights into the role of COX-2 in inflammation. J Mol Med 2000; 78: 121-9.
    • (2000) J Mol Med , vol.78 , pp. 121-129
    • Gilroy, D.1    Colville-Nash, P.R.2
  • 2
    • 0027722115 scopus 로고
    • Cyclooxygenase gene expression in inflammation and angiogenesis
    • Hla T, Ristimaki A, Appleby S, Barriocana JG. Cyclooxygenase gene expression in inflammation and angiogenesis. Ann NY Acad Sci 1993; 696: 197-204.
    • (1993) Ann NY Acad Sci , vol.696 , pp. 197-204
    • Hla, T.1    Ristimaki, A.2    Appleby, S.3    Barriocana, J.G.4
  • 3
  • 4
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • FitzGerald GA, Patrono C. The Coxibs, Selective Inhibitors of Cyclooxygenase-2. N Engl J Med 2001; 345: 433-42.
    • (2001) N Engl J Med , vol.345 , pp. 433-442
    • FitzGerald, G.A.1    Patrono, C.2
  • 5
    • 0026531534 scopus 로고
    • In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis
    • Sano H, Hla T, Maier JA, Crofford LJ, Maciag T, Wilder RL. In Vivo Cyclooxygenase Expression in Synovial Tissues of Patients with Rheumatoid Arthritis and Osteoarthritis and Rats with Adjuvant and Streptococcal Cell Wall Arthritis. J Clin Invest 1992; 89: 97-108.
    • (1992) J Clin Invest , vol.89 , pp. 97-108
    • Sano, H.1    Hla, T.2    Maier, J.A.3    Crofford, L.J.4    Maciag, T.5    Wilder, R.L.6
  • 6
    • 0028783397 scopus 로고
    • Functional interactions of T cells with endothelial cells: The role of CD40L-CD40-mediated signals
    • Yellin MJ, Brett J, Baum D, Matsushima A, Szabolcs M, Stern D et al. Functional Interactions of T Cells with Endothelial Cells: The Role of CD40L-CD40-mediated Signals. J Exp Med 1995; 182: 1857-64.
    • (1995) J Exp Med , vol.182 , pp. 1857-1864
    • Yellin, M.J.1    Brett, J.2    Baum, D.3    Matsushima, A.4    Szabolcs, M.5    Stern, D.6
  • 8
    • 0026340762 scopus 로고
    • COX gene expression is down-regulated by heparin-binding (acidic fibroblast) growth factor-1 in human endothelial cells
    • Hla T, Maciag T. COX gene expression is down-regulated by heparin-binding (acidic fibroblast) growth factor-1 in human endothelial cells. J Biol Chem 1991; 266: 24059-63.
    • (1991) J Biol Chem , vol.266 , pp. 24059-24063
    • Hla, T.1    Maciag, T.2
  • 9
    • 0030590429 scopus 로고    scopus 로고
    • Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: A possible site of prostaglandin synthesis responsible for fever
    • Cao C, Matsumura K, Yamagata K, Watanabe Y. Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever. Brain Res 1996; 733: 263-72.
    • (1996) Brain Res , vol.733 , pp. 263-272
    • Cao, C.1    Matsumura, K.2    Yamagata, K.3    Watanabe, Y.4
  • 12
    • 0031771180 scopus 로고    scopus 로고
    • CD40 in clinical inflammation: From multiple sclerosis to atherosclerosis
    • Laman JD, De Boer M, Hart BA. CD40 in clinical inflammation: from multiple sclerosis to atherosclerosis. Develop Immunol 1998; 6: 215-22.
    • (1998) Develop Immunol , vol.6 , pp. 215-222
    • Laman, J.D.1    De Boer, M.2    Hart, B.A.3
  • 17
    • 0033529170 scopus 로고    scopus 로고
    • Inhibition of prostaglandin E2 synthesis in abdominal aortic aneurysms: Implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms
    • Walton LJ, Franklin IJ, Bayston T, Brown LC, Greenhalgh RM, Taylor GW et al. Inhibition of prostaglandin E2 synthesis in abdominal aortic aneurysms: implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms. Circulation 1999; 100: 48-54.
    • (1999) Circulation , vol.100 , pp. 48-54
    • Walton, L.J.1    Franklin, I.J.2    Bayston, T.3    Brown, L.C.4    Greenhalgh, R.M.5    Taylor, G.W.6
  • 18
    • 0033803843 scopus 로고    scopus 로고
    • Effect of phenytoin on the production of interleukin-6 and interleukin-8 in human gingival fibroblasts
    • Modeer T, Domeij H, Anduren I, Mustafa M, Brunius G. Effect of phenytoin on the production of interleukin-6 and interleukin-8 in human gingival fibroblasts. J Oral Pathol Med 2000; 29: 491-9.
    • (2000) J Oral Pathol Med , vol.29 , pp. 491-499
    • Modeer, T.1    Domeij, H.2    Anduren, I.3    Mustafa, M.4    Brunius, G.5
  • 22
    • 0028858649 scopus 로고
    • Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes
    • Kiener PA, Moran-Davis P, Rankin BM, Wahl AF, Aruffo A, Hollenbaugh D. Stimulation of CD40 with Purified Soluble gp39 Induces Proinflammatory Responses in Human Monocytes. J Immunol 1995; 155: 4917-25.
    • (1995) J Immunol , vol.155 , pp. 4917-4925
    • Kiener, P.A.1    Moran-Davis, P.2    Rankin, B.M.3    Wahl, A.F.4    Aruffo, A.5    Hollenbaugh, D.6
  • 23
    • 0029033142 scopus 로고
    • Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD 106 (VCAM-1) up-regulation and IL-6 production and proliferation
    • Yellin MJ, Winikoff S, Fortune SM, Baum D, Crow MK, Lederman S et al. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD 106 (VCAM-1) up-regulation and IL-6 production and proliferation. J Leukocyte Biol 1995; 58: 209-16.
    • (1995) J Leukocyte Biol , vol.58 , pp. 209-216
    • Yellin, M.J.1    Winikoff, S.2    Fortune, S.M.3    Baum, D.4    Crow, M.K.5    Lederman, S.6
  • 24
    • 0028089109 scopus 로고
    • NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro
    • Futaki N, Takahashi S, Yokoyama M, Arai I, Higuchi S, Otomo S. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins 1994; 47: 55-9.
    • (1994) Prostaglandins , vol.47 , pp. 55-59
    • Futaki, N.1    Takahashi, S.2    Yokoyama, M.3    Arai, I.4    Higuchi, S.5    Otomo, S.6
  • 25
    • 0034069409 scopus 로고    scopus 로고
    • Inducible cyclooxygenase-2 gene expression in the human thyroid epithelial cell line Nthy-ori3-1
    • Berg J, Stocher M, Bogner S, Wolff S, Pichler R, Stekel H. Inducible cyclooxygenase-2 gene expression in the human thyroid epithelial cell line Nthy-ori3-1. Inflamm Res 2000; 49: 139-43.
    • (2000) Inflamm Res , vol.49 , pp. 139-143
    • Berg, J.1    Stocher, M.2    Bogner, S.3    Wolff, S.4    Pichler, R.5    Stekel, H.6
  • 26
  • 27
    • 0033973713 scopus 로고    scopus 로고
    • Molecular pathology of cyclooxygenase-2 in neoplasia
    • Fosslien E. Molecular pathology of cyclooxygenase-2 in neoplasia. Ann Clin Lab Sci 2000; 30: 3-21.
    • (2000) Ann Clin Lab Sci , vol.30 , pp. 3-21
    • Fosslien, E.1
  • 28
    • 0029888972 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of Cox-2 and interleukin 6 in rat adjuvant arthritis
    • Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory SA. Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of Cox-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996; 97: 2672-9.
    • (1996) J Clin Invest , vol.97 , pp. 2672-2679
    • Anderson, G.D.1    Hauser, S.D.2    McGarity, K.L.3    Bremer, M.E.4    Isakson, P.C.5    Gregory, S.A.6
  • 29
    • 0026761179 scopus 로고
    • Prostanoid biosynthesis and mechanisms of action
    • Ž
    • Smith WL. Prostanoid biosynthesis and mechanisms of action. Am Physiol 1992; 263Ž: F181-91.
    • (1992) Am Physiol , vol.263
    • Smith, W.L.1
  • 30
    • 0032796071 scopus 로고    scopus 로고
    • Regulation and metabolism of arachidonic acid
    • 1999
    • Seeds MC, Bass DA. Regulation and Metabolism of Arachidonic Acid. 1999. Clin Rev Allergy Immunol 1999; 17: 5-21.
    • (1999) Clin Rev Allergy Immunol , vol.17 , pp. 5-21
    • Seeds, M.C.1    Bass, D.A.2
  • 31
    • 0030985587 scopus 로고    scopus 로고
    • Selective induction of cyclooxygenase-2 activity in the permanent human endothelial cell line HUV-EC-C: Biochemical and pharmacological characterization
    • Miralpeix M, Camacho M, Lopez-Belmonte J, Canalias F, Beleta J, Palacios JM et al. Selective induction of cyclooxygenase-2 activity in the permanent human endothelial cell line HUV-EC-C: biochemical and pharmacological characterization. Br J Pharmacol 1997; 121: 171-80.
    • (1997) Br J Pharmacol , vol.121 , pp. 171-180
    • Miralpeix, M.1    Camacho, M.2    Lopez-Belmonte, J.3    Canalias, F.4    Beleta, J.5    Palacios, J.M.6
  • 32
    • 1842406550 scopus 로고    scopus 로고
    • Ligation of CD40 activates interleukin 1β-converting enzyme (Caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1 β
    • Schonbeck U, Mach F, Bonnefoy J-Y, Loppnow H, Flad H-D, Libby P. Ligation of CD40 Activates Interleukin 1β-converting Enzyme (Caspase-1) Activity in Vascular Smooth Muscle and Endothelial Cells and Promotes Elaboration of Active Interleukin 1 β. J Biol Chem 1997; 272: 19569-74.
    • (1997) J Biol Chem , vol.272 , pp. 19569-19574
    • Schonbeck, U.1    Mach, F.2    Bonnefoy, J.-Y.3    Loppnow, H.4    Flad, H.-D.5    Libby, P.6
  • 34
    • 0034779037 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 protein by lipoteichoic acid from Staphylococcus aureus in human pulmonary epithelial cells: Involvement of a nuclear factor-kappa B-dependent pathway
    • Lin CH, Kuan IH, Lee HM, Lee WS, Sheu JR, Ho YS et al. Induction of cyclooxygenase-2 protein by lipoteichoic acid from Staphylococcus aureus in human pulmonary epithelial cells: involvement of a nuclear factor-kappa B-dependent pathway. Br J Pharmacol 2001; 134: 543-52.
    • (2001) Br J Pharmacol , vol.134 , pp. 543-552
    • Lin, C.H.1    Kuan, I.H.2    Lee, H.M.3    Lee, W.S.4    Sheu, J.R.5    Ho, Y.S.6
  • 35
    • 0032749315 scopus 로고    scopus 로고
    • Antisense IPAK-2 oligonucleotide blocks IL-1-stimulated NF-kappaB activation and ICAM-1 expression in cultured endothelial cells
    • Guo F, Li Y, Wu S. Antisense IPAK-2 oligonucleotide blocks IL-1-stimulated NF-kappaB activation and ICAM-1 expression in cultured endothelial cells. Inflammation 1999; 23: 535-43.
    • (1999) Inflammation , vol.23 , pp. 535-543
    • Guo, F.1    Li, Y.2    Wu, S.3
  • 36
    • 0031739197 scopus 로고    scopus 로고
    • Production of reactive oxygen intermediates following CD40 ligation correlates with c-Jun N-terminal kinase activation and IL-6 secretion in murine B lymphocytes
    • Lee JR, Koretzky GA. Production of reactive oxygen intermediates following CD40 ligation correlates with c-Jun N-terminal kinase activation and IL-6 secretion in murine B lymphocytes. Eur J Immunol 1998; 28: 4188-97.
    • (1998) Eur J Immunol , vol.28 , pp. 4188-4197
    • Lee, J.R.1    Koretzky, G.A.2
  • 37
    • 0028892530 scopus 로고
    • CD40 function in nonhematopoietic cells. Nuclear factor κB mobilization and induction of IL-6 production
    • Hess S, Rensing-Ehl A, Schwabe R, Bufler P, Engelmann H. CD40 Function in Nonhematopoietic Cells. Nuclear Factor κB Mobilization and Induction of IL-6 Production. J Immunol 1995; 155: 4588-95.
    • (1995) J Immunol , vol.155 , pp. 4588-4595
    • Hess, S.1    Rensing-Ehl, A.2    Schwabe, R.3    Bufler, P.4    Engelmann, H.5
  • 39
    • 0034667890 scopus 로고    scopus 로고
    • Autoregulation of human monocyte-derived dendritic cell maturation and IL-12 production by cyclooxygenase-2-mediated prostanoid production
    • Whittaker DS, Bahjat KS, Moldawer LL, Clare-Salzler MJ. Autoregulation of Human Monocyte-Derived Dendritic Cell Maturation and IL-12 Production by Cyclooxygenase-2-Mediated Prostanoid Production. J Immunol 2000; 165: 4298-304.
    • (2000) J Immunol , vol.165 , pp. 4298-4304
    • Whittaker, D.S.1    Bahjat, K.S.2    Moldawer, L.L.3    Clare-Salzler, M.J.4
  • 40
    • 0032529226 scopus 로고    scopus 로고
    • Requirement for dual signals by anti-CD40 and IL-4 for the induction of nuclear factor-κB, 1L-6, and IgE in human B lymphocytes
    • Jeppson JD, Patel HR, Sakata N, Domenico J, Terada N, Gelfand EW. Requirement for Dual Signals by Anti-CD40 and IL-4 for the Induction of Nuclear Factor-κB, 1L-6, and IgE in Human B Lymphocytes. J Immunol 1998; 161: 1738-42.
    • (1998) J Immunol , vol.161 , pp. 1738-1742
    • Jeppson, J.D.1    Patel, H.R.2    Sakata, N.3    Domenico, J.4    Terada, N.5    Gelfand, E.W.6
  • 41
    • 0032711248 scopus 로고    scopus 로고
    • Membrane-bound CD154, but not CD40-specific antibody, mediates NF-κB-independent IL-6 production in B cells
    • Baccam M, Bishop GA. Membrane-bound CD154, but not CD40-specific antibody, mediates NF-κB-independent IL-6 production in B cells. Eur J Immunol 1999; 29: 3855-66.
    • (1999) Eur J Immunol , vol.29 , pp. 3855-3866
    • Baccam, M.1    Bishop, G.A.2
  • 42
    • 0028152658 scopus 로고
    • Cross-linking CD40 in B cells rapidly activates nuclear factor-kappa B
    • Berberich I, Shu GL, Clark EA. Cross-linking CD40 in B cells rapidly activates nuclear factor-kappa B. J Immunol 1994; 153: 4357-66
    • (1994) J Immunol , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 43
    • 0034130124 scopus 로고    scopus 로고
    • Pyrimidinoceptor potentiation of macrophage PGE(2) release involved in the induction of nitric oxide synthase
    • Chen BC, Lin WW. Pyrimidinoceptor potentiation of macrophage PGE(2) release involved in the induction of nitric oxide synthase. Br J Pharmacol 2000; 130: 777-86.
    • (2000) Br J Pharmacol , vol.130 , pp. 777-786
    • Chen, B.C.1    Lin, W.W.2
  • 44
    • 0032133297 scopus 로고    scopus 로고
    • Increased presence of interleukin-6 (IL-6) and IL-8 secreting fibroblast subpopulations in adult periodontitis
    • Dongari-Bagtzoglou AI, Ebersole JL. Increased presence of interleukin-6 (IL-6) and IL-8 secreting fibroblast subpopulations in adult periodontitis. J Periodontol 1998; 69: 899-910.
    • (1998) J Periodontol , vol.69 , pp. 899-910
    • Dongari-Bagtzoglou, A.I.1    Ebersole, J.L.2
  • 45
    • 0035318704 scopus 로고    scopus 로고
    • COX-2 expression is upregulated in inflamed gingival tissues
    • Sinha-Morton R, Dongari-Bagtzoglou AI. COX-2 expression is upregulated in inflamed gingival tissues. J Periodontol 2001; 72: 461-9.
    • (2001) J Periodontol , vol.72 , pp. 461-469
    • Sinha-Morton, R.1    Dongari-Bagtzoglou, A.I.2
  • 46
    • 0025274640 scopus 로고
    • Cytokines & cytokine inhibitors or antagonists in rheumatoid arthritis
    • Arend WP, Dayer JM. Cytokines & cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 1990; 33: 305-15.
    • (1990) Arthritis Rheum , vol.33 , pp. 305-315
    • Arend, W.P.1    Dayer, J.M.2
  • 47
    • 17144454444 scopus 로고    scopus 로고
    • Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions
    • Hong BK, Kwon HM, Lee BK, Kim IJ, Kang SM, Jang Y et al. Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions. Yonsei Med J 2000; 41: 82-8.
    • (2000) Yonsei Med J , vol.41 , pp. 82-88
    • Hong, B.K.1    Kwon, H.M.2    Lee, B.K.3    Kim, I.J.4    Kang, S.M.5    Jang, Y.6
  • 48
    • 0034702914 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis
    • Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation 2000; 102: 840-5.
    • (2000) Circulation , vol.102 , pp. 840-845
    • Belton, O.1    Byrne, D.2    Kearney, D.3    Leahy, A.4    Fitzgerald, D.J.5
  • 50
    • 0031049711 scopus 로고    scopus 로고
    • Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40-CD40 ligand signaling in atherosclerosis
    • Mach F, Schonbeck U, Sukhova G, Bourcier T, Bonnefoy J-Y, Pober JS et al. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: Implications for CD40-CD40 ligand signaling in atherosclerosis. Proc Natl Acad Sci USA 1997; 94: 1931-6.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1931-1936
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.3    Bourcier, T.4    Bonnefoy, J.-Y.5    Pober, J.S.6
  • 51
    • 0033870357 scopus 로고    scopus 로고
    • Analysis of CD154 and CD40 expression in native coronary atherosclerosis and transplant associated coronary artery disease
    • Szabolcs MJ, Cannon PJ, Thienel U, Chen R, Michler RE, Chess L et al. Analysis of CD154 and CD40 expression in native coronary atherosclerosis and transplant associated coronary artery disease. Virchows Arch 2000; 437: 149-59.
    • (2000) Virchows Arch , vol.437 , pp. 149-159
    • Szabolcs, M.J.1    Cannon, P.J.2    Thienel, U.3    Chen, R.4    Michler, R.E.5    Chess, L.6
  • 52
    • 0032916346 scopus 로고    scopus 로고
    • Differential expression of costimulatory molecules in chronic inflammatory periodontal disease tissue
    • Orima K, Yamazaki K, Aoyagi T, Hara K. Differential expression of costimulatory molecules in chronic inflammatory periodontal disease tissue. Clin Exp Immunol 1999; 115: 153-60.
    • (1999) Clin Exp Immunol , vol.115 , pp. 153-160
    • Orima, K.1    Yamazaki, K.2    Aoyagi, T.3    Hara, K.4
  • 53
    • 0027816953 scopus 로고
    • Prevention of collagen induced arthritis with an antibody to gp39, the ligand for CD40
    • Durie F, Faua R, Foy T, Aruffo A, Ledbetter JL, Noelle R. Prevention of collagen induced arthritis with an antibody to gp39, the ligand for CD40. Science 1993; 261: 1328-30.
    • (1993) Science , vol.261 , pp. 1328-1330
    • Durie, F.1    Faua, R.2    Foy, T.3    Aruffo, A.4    Ledbetter, J.L.5    Noelle, R.6
  • 54
    • 0032387823 scopus 로고    scopus 로고
    • Blockade of CD40-CD40 ligand interactions protects against radiation-induced pulmonary inflammation and fibrosis
    • Adawi A, Zhang Y, Baggs R, Rubin P, Williams J, Finkelstein J et al. Blockade of CD40-CD40 Ligand Interactions Protects against Radiation-Induced Pulmonary Inflammation and Fibrosis. Clin Immunol Immunopathol 1998; 89: 222-30.
    • (1998) Clin Immunol Immunopathol , vol.89 , pp. 222-230
    • Adawi, A.1    Zhang, Y.2    Baggs, R.3    Rubin, P.4    Williams, J.5    Finkelstein, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.