CD40 expression by gingival fibroblasts: Correlation of phenotype with function

International Immunology

Volumn 9, Issue 9, 1997, Pages 1233-1241

  Dongari Bagtzoglou, Anna I ^a   Warren, Wendy D ^b   Berton, Michael T ^b   Ebersole, Jeffrey L ^b  

^a Columbia University ^*  (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

CD40; Cytokines; Gingival fibroblast; Heterogeneity

Indexed keywords

CD40 ANTIGEN; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CELL SUBPOPULATION; CELL TYPE; CONTROLLED STUDY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; REGRESSION ANALYSIS;

ANTIGENS, CD40; CD40 LIGAND; CELLS, CULTURED; FIBROBLASTS; GINGIVA; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LIGANDS; MEMBRANE GLYCOPROTEINS;

EID: 0030860205     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.9.1233     Document Type: Article

References (44)

1. Stamenkovic, I., Clark, E. A. and Seed, B. 1989. A B lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8:1403.
2. Hollenbaugh, D., Mischel-Petty N., Edwards, C. P., Simon, J. C., Denfeld, R. W., Kiener, P. A. and Aruffo, A. 1995. Expression of functional CD40 by vascular endothelial cells. J. Exp. Med. 182:33.
3. Fries, K. M., Sempowski, G. D., Gaspari, A. A., Blieden, T., Looney, R. J. and Phipps, R. P. 1995. CD40 expression by human fibroblasts. Clin. Immunol. Immunopathol. 77:42.
4. Armitage, R. J., Fanslow, W. C., Strockbine, L., Sato, T. A., Clifford, K. N., Macduff, B. M. Anderson, D. M., Gimpel, S. D., Davis-Smith, T., Maliszewski, C. R., Clark, E. A., Smith, C. A., Grabstein K. H., Cosman, D. and Spriggs, M. K. 1992. Molecular and biological characterization of a murine ligand for CD40. Nature 357:80.
5. Noelle, R. J., Roy, M., Shepherd, D. M., Stamenkovic I., Ledbetter, J. A. and Aruffo, A. 1992. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl Acad. Sci. USA 89:6550.
6. Noelle, R. J., Ledbetter, J. A, and Aruffo, A. 1992. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation, Immunol Today. 13:431.
7. Grewal, I. S., Xu, J. and Flavell, R. A. 1995. Impairment of antigen-specific cell priming in mice lacking CD40 ligand. Nature 378:617
8. Van Essen, D., Kikutani, H. and Gray, D. 1995. CD40 ligand-transduced co-stimulation of T cells in the development of helper function. Nature 378:620.
9. Yellin, M. J., Winikoff, S., Fortune, S. M., Baum, D., Crow, M. K., Lederman, S. and Chess, L. 1995. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation. J. Leuk. Biol. 58:209.
10. Arend, W. P. and Dayer, J. M. 1990. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum. 33:305.
11. Schroeder, H. E. and Page, R. C. 1972. Lymphocyte-fibroblast interaction in the pathogenesis of inflammatory gingival disease. Experientia 28:1228.
12. Dongari-Bagtzoglou, A. I. and Ebersole, J. L. 1996. Production of inflammatory mediators and cytokines by human gingival fibroblasts following bacterial challenge. J. Periodont. Res. 31:90.
13. Bartold, P. M. and Haynes, D. R. 1991. Interleukin 6 production by human gingival fibroblasts, J. Periodont. Res. 26:339.
14. Alderson, M. R., Armitage, R. J., Tough, T. W., Strockbine, L., Fanslow, W. C. and Spriggs, M. K. 1993. CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. J. Exp. Med. 178:669.
15. Gruss, H. J., Ulrich, D., Braddy, S., Armitage, R. J. and Dower, S. K. 1995. Recombinant CD30 ligand and CD40 ligand share common biological activities on Hodgkin and Reed-Sternberg cells. Eur. J. Immunol. 25:2083.
16. - lung fibroblast subpopulations: enhancement of Interleukin 1α production by TNFα. Eur. J. Immunol. 20:1723.
17. Breen, E. and Cutroneo, K, R. 1992. Biochemical and molecular aspects of pulmonary fibroblast heterogeneity. In Phipps, R. P., ed., Pulmonary Fibroblast Heterogeneity, p. 27. CRC Press, Boca Raton, FL.
18. Phipps, R. P. and Blieden, T. 1995. Fibroblast heterogeneity in the periodontium and other tissues. In Proc. Int. Conf. on Periodontal Research. Western, NY, September 13-17.
19. Irwin, C. R., Schor, S. L. and Ferguson, M. W. J. 1994. Effects of cytokines on gingival fibroblasts in vitro are modulated by the extracellular matrix. J. Periodont. Res. 29:309.
20. + T cells by a rat monoclonal antibody, 14D10. J. Immunol. 129:81.
21. Warren, W. D. and Berton, M. T. 1995. Induction of germ-line γ1 and ε Ig gene expression in murine B cells: IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals J. Immunol. 155:5637.
22. Armitage, R. J., Sato, T. A., Macduff, B. M., Clifford, K. N., Alpert, A., Smith, C. A. and Fanslow, W. C. 1992. Identification of a source of biologically active CD40 ligand. Eur. J. Immunol. 22:2071.
23. Karmann, K., Hughes, C. C. W., Schechner, J., Fanrlow, W. C. and Pober, J. S. 1995. CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. Proc. Natl Acad. Sci. USA 92:4342
24. Dongari-Bagtzoglou, A. I. and Ebersole, J. L. 1996. Application of immunoprinting for assessment of fibroblast secretory heterogeneity. J. Immunol. Methods 198:145.
25. Pious, D. A., Hamburger, R. N. and Mills, S. E. 1964. Clonal growth of primary human cell cultures. Exp. Cell Res. 33:495.
26. 2 synthetic capacity of substrains are not stimulus-restricted. Arthritis Rheum. 28:315.
27. Korn, J. H. 1984. Clonal heterogeneity in the fibroblast response to mononuclear cell derived mediators. Arthritis Rheum. 27:174.
28. Hess, S., Rensing-Ehl, A., Schwabe, R., Butler, P. and Engelmann, H. 1995. CD40 function in non-hematopoietic cells. Nuclear factor kB mobilization and induction of IL-6 production. J. Immunol. 155:4588.
29. Matsusaka, T., Fujikawa, K., Nishio, Y., Mukaida N., Matsushima, K., Kishimito, T. and Akira, S. 1993. Transcription factors NF-IL6 and NF-kB synergistically activate transcription of the inflammatory cytokines IL-6 and IL-8. Proc Natl Acad. Sci. USA 90:10193.
30. Clark, E. A. and Shu, G. 1990. Association between IL-6 and CD40 signaling. IL-6 induces phosphorylation of CD40 receptors. J. Immunol. 145:1400.
31. Hollenbaugh, D., Grosmaire, L. S., Kallas, C. D., Chalupny, N. J., Braesch-Andersen, S., Noelle, R. J., Stamencovic, I., Ledbetter. J. A. and Aruffo, A. 1992. The human T cell antigen gp39, a member of the TNF gene family. is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell costimulatory activity. EMBO J. 11:4313.
32. Wahl, S. M., Hunt, D. A., Allen, J, B., Wilder, R. L., Paglia, L. and Hand, A. R. 1986. Bacterial cell wall-induced hepatic granulomas: an in vivo model of T cell-dependent fibrosis. J. Exp Med. 163:884.
33. Ishikawa, H. and Ziff, M. 1976. Electron microscopic observations of immunoreactive cells in the rheumatoid synovial membrane. Arthritis Rheum. 19:1.
34. Borrello, M. A. and Phipps, R. P. 1996. Differential Thy-1 expression by splenic fibroblasts defines functionally distinct subsets. Cell. Immunol. 173:198.
35. Zwadlo, G., Voegeli, R., Schulze Osthoff, K. and Sorg, C. 1987. A monoclonal antibody to a novel differentiation antigen on human macrophages associated with the down-regulatory phase of the inflammatory process. Exp. Cell Biol. 55:295.
36. Zwadlo, G., Schlegel, R. and Sorg, C. 1986. A monoclonal antibody to a subset of human monocytes found only in the peripheral blood and inflammatory tissues. J. Immunol. 137:512.
37. Potocnik, A. J., Kinne, R., Menninger, H., Zacher, J., Emmrich, F. and Kroczek, R. A. 1990, Expression of activation antigens on T cells in rheumatoid arthritis patients, Scand. J. Immunol. 31:213.
38. Takahashi, K, S., Takashiba, S., Nagai, A., Takigawa, M., Miyoukai, F, Kurihawa, H. and Murayama, Y. 1994. Assessment of interleukin-6 in the pathogenesis of periodontal disease. J. Periodontol. 65:147.
39. Remick, D. G., DeForge, L E., Sullivan, J. F. and Showell, H. J. 1992. Profile of cytokines in synovial fluid specimens from patients with arthritis, lnterleukin 8 (IL-8) and IL-6 correlate with inflammatory arthritides. Immunol. Invest. 21:321.
40. Mundy, G. R. 1991. Inflammatory mediators and the destruction of bone. J. Periodont. Res. 26:213.
41. Poli, V., Balena, R., Fattori, E., Markatos, A., Yamamoto, M., Tanaka, H., Ciliberto, G., Rodan, G. A. and Costantini, F 1994. lnterleukin 6-deficient mice are protected from bone loss caused by estrogen depletion, EMBO J. 13:11189.
42. Fries, K. M., Felch. M. E. and Phipps, R. P. 1994, Interleukin 6 is an autocrine growth factor for murine lung fibroblast subsets. Am. J. Respir. Cell Mol. Biol. 11:552
43. Larsen, C. G., Anderson, A. O., Apella, E., Openheim, J. J. and Matsusima, K. 1989. Neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes. Science 243:1464.
44. Durie, F. H., Foy, T. M. and Noelle, R. J. 1993. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand to CD40. Science 261:1328.