Selective induction of cyclo-oxygenase-2 activity in the permanent human endothelial cell line HUV-EC-C: Biochemical and pharmacological characterization

British Journal of Pharmacology

Volumn 121, Issue 2, 1997, Pages 171-180

  Miralpeix, Montserrat ^a   Camacho, Mercedes ^a   López Belmonte, Jesús ^a   Canalías, Francesca ^b   Beleta, Jordi ^b   Palacios, José Ma ^b   Vila, Luis ^a,c  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b Laboratories Almirall SA ^*  (Spain)

^c HS Creu I S Pau   (Spain)

Author keywords

COX 1; COX 2; Endothelial cell line; Human platelets; HUV EC C; Inducible cyclo oxygenase; Interleukin 1; Nimesulide; NS 398; NSAID; Phorbol 12 myristate 13 acetate; SC 58125

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 2; ICOSANOID; INTERLEUKIN 1BETA; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN E2; PROSTAGLANDIN H2; PROSTANOID;

ARTICLE; BIOCHEMISTRY; CELL LINE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG POTENCY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; MESSENGER RNA SYNTHESIS; PRIORITY JOURNAL; SYNTHESIS; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

EID: 0030985587     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701112     Document Type: Article

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