메뉴 건너뛰기




Volumn 113, Issue 2, 2000, Pages 101-116

Isolating aging mutants: A novel method yields three strains of the nematode Caenorhabditis elegans with extended life spans

Author keywords

Aging; C. elegans; Heat shock; Life span; Longevity; Mutant

Indexed keywords

AGING; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; FEEDING BEHAVIOR; FERTILITY; HEAT SHOCK; HEAT STRESS; HERMAPHRODITISM; LIFESPAN; LOCOMOTION; LONGEVITY; MALE; MATING; MUTANT; NEMATODE; NONHUMAN; PRIORITY JOURNAL; TECHNIQUE;

EID: 0033979686     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(99)00100-1     Document Type: Article
Times cited : (15)

References (28)
  • 1
    • 0027384878 scopus 로고
    • Retarded senescence in an insular population of Virginia opossums (Didelphis virginiana)
    • Austad S.N. Retarded senescence in an insular population of Virginia opossums (Didelphis virginiana). J. Zool. 229:1993;695-708.
    • (1993) J. Zool. , vol.229 , pp. 695-708
    • Austad, S.N.1
  • 2
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. The genetics of Caenorhabditis elegans. Genetics. 77:1974;71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 4
    • 0023678537 scopus 로고
    • Three mutants that extend both mean and maximum life span of the nematode Caenorhabditis elegans, define the age-1 gene
    • Friedman D.B., Johnson T.E. Three mutants that extend both mean and maximum life span of the nematode Caenorhabditis elegans, define the age-1 gene. J. Gerontol. 43(4):1988;B102-109.
    • (1988) J. Gerontol. , vol.43 , Issue.4 , pp. 102-109
    • Friedman, D.B.1    Johnson, T.E.2
  • 5
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • Friedman D.B., Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics. 118:1988;75-86.
    • (1988) Genetics , vol.118 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 7
    • 1842398374 scopus 로고
    • Genetic analysis of life span in Caenorhabditis elegans
    • Johnson T.E., Wood W.B. Genetic analysis of life span in Caenorhabditis elegans. Proc. Natl. Acad. Sci. 79:1982;6603-6607.
    • (1982) Proc. Natl. Acad. Sci. , vol.79 , pp. 6603-6607
    • Johnson, T.E.1    Wood, W.B.2
  • 8
    • 0027771804 scopus 로고
    • A C. elegans that lives twice as long as wild-type
    • Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. A C. elegans that lives twice as long as wild-type. Nature. 366:1993;461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 9
    • 0000174508 scopus 로고    scopus 로고
    • Environmental factors and gene activities that influence life span
    • D.L. Riddle, T. Blumenthal, B.J. Meyer, & J.R. Priess. New York: Cold Spring Harbor Laboratory
    • Kenyon C Environmental factors and gene activities that influence life span. Riddle D.L., Blumenthal T., Meyer B.J., Priess J.R. C. elegans II. 1997;791-813 Cold Spring Harbor Laboratory, New York.
    • (1997) C. Elegans II , pp. 791-813
    • Kenyon, C.1
  • 10
    • 0002845420 scopus 로고    scopus 로고
    • Germ-line development and fertilization
    • W.B. et al. Wood. New York: Cold Spring Harbor Laboratory
    • Kimble J., Ward S. Germ-line development and fertilization. Wood W.B. et al. The Nematode Caenorhabditis elegans. 1998;191-213 Cold Spring Harbor Laboratory, New York.
    • (1998) The Nematode Caenorhabditis Elegans , pp. 191-213
    • Kimble, J.1    Ward, S.2
  • 11
    • 0002141947 scopus 로고
    • Comparative evolutionary aspects of longevity
    • C.E. Finch, & E.L. Schneider. New York: Van Nostrand
    • Kirkwood T.B. Comparative evolutionary aspects of longevity. Finch C.E., Schneider E.L. Handbook of the Biology of Aging. 2nd ed:1985;27-45 Van Nostrand, New York.
    • (1985) Handbook of the Biology of Aging 2nd Ed , pp. 27-45
    • Kirkwood, T.B.1
  • 12
    • 0001904727 scopus 로고
    • The disposable soma theory of ageing
    • D.E. Harrison. New Jersey: Telford Press
    • Kirkwood T.B. The disposable soma theory of ageing. Harrison D.E. Genetic Effects on Aging II. 1990;9-19 Telford Press, New Jersey.
    • (1990) Genetic Effects on Aging II , pp. 9-19
    • Kirkwood, T.B.1
  • 13
    • 0017763799 scopus 로고
    • Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span
    • Klass M.R. Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span. Mech. Aging. Dev. 6:1977;413-429.
    • (1977) Mech. Aging. Dev. , vol.6 , pp. 413-429
    • Klass, M.R.1
  • 14
    • 0021056471 scopus 로고
    • A method for isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results
    • Klass M.R. A method for isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results. Mech. Aging. Dev. 22:1983;279-286.
    • (1983) Mech. Aging. Dev. , vol.22 , pp. 279-286
    • Klass, M.R.1
  • 15
    • 0029776793 scopus 로고    scopus 로고
    • Determination of life-span in Caenorhabditis elegans by four clock genes
    • Lakowski B., Hekimi S Determination of life-span in Caenorhabditis elegans by four clock genes. Science. 272:1996;1010-1013.
    • (1996) Science , vol.272 , pp. 1010-1013
    • Lakowski, B.1    Hekimi, S.2
  • 16
    • 0027515616 scopus 로고
    • Aging and resistance to oxidative damage in Caenorhabditis elegans
    • Larsen P.L. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 90:1993;8905-8909.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8905-8909
    • Larsen, P.L.1
  • 17
    • 0027945612 scopus 로고
    • Thermotolerance of a long lived mutant of Caenorhabditis elegans
    • Lithgow G.J., White T.M., Hinerfeld D.A., Johnson T.E. Thermotolerance of a long lived mutant of Caenorhabditis elegans. J. Gerontol. 49(6):1994;B270-B276.
    • (1994) J. Gerontol. , vol.49 , Issue.6
    • Lithgow, G.J.1    White, T.M.2    Hinerfeld, D.A.3    Johnson, T.E.4
  • 18
    • 0029123058 scopus 로고
    • Thermotolerance and extended life span conferred by single-gene mutations and induced by thermal stress
    • Lithgow G.J., White T.M., Melov S., Johnson T.E. Thermotolerance and extended life span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. USA. 92:1995;7540-7544.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7540-7544
    • Lithgow, G.J.1    White, T.M.2    Melov, S.3    Johnson, T.E.4
  • 19
    • 0032860509 scopus 로고    scopus 로고
    • Kleemeier award lecture: Are there genes for aging?
    • Miller R.A. Kleemeier award lecture: are there genes for aging? J. Gerontol. 54A(7):1999;B297-B307.
    • (1999) J. Gerontol. , vol.54 , Issue.7
    • Miller, R.A.1
  • 20
    • 0342960104 scopus 로고
    • Some aspect of aging can be studied easily in nematodes
    • C.E. Finch, & E.L. Schneider. New York: Van Nostrand Reinhold
    • Russell R.L., Jacobson L.A. Some aspect of aging can be studied easily in nematodes. Finch C.E., Schneider E.L. Handbook of the Biology of Aging. 1985;128-145 Van Nostrand Reinhold, New York.
    • (1985) Handbook of the Biology of Aging , pp. 128-145
    • Russell, R.L.1    Jacobson, L.A.2
  • 21
    • 0027197284 scopus 로고
    • Oxidative stress and aging in Caenorhabditis elegans
    • Vanfleteren J.R. Oxidative stress and aging in Caenorhabditis elegans. Biochem. J. 292:1993;605-608.
    • (1993) Biochem. J. , vol.292 , pp. 605-608
    • Vanfleteren, J.R.1
  • 22
    • 0026614114 scopus 로고
    • Production of sperm reduces nematode life span
    • Van Voorhies W.A. Production of sperm reduces nematode life span. Nature. 360:1992;456-458.
    • (1992) Nature , vol.360 , pp. 456-458
    • Van Voorhies, W.A.1
  • 23
    • 0001771082 scopus 로고
    • Anatomy
    • W.B. et al. Wood. New York: Cold Spring Harbor Laboratory
    • White J. Anatomy. Wood W.B. et al. The Nematode Caenorhabditis elegans. 1988;81-122 Cold Spring Harbor Laboratory, New York.
    • (1988) The Nematode Caenorhabditis Elegans , pp. 81-122
    • White, J.1
  • 24
    • 0002942195 scopus 로고
    • The programmed theory of aging
    • M. Rockstein. New York: Academic Press
    • Wilson D.L. The programmed theory of aging. Rockstein M. Theoretical Aspects of Aging. 1974;11-21 Academic Press, New York.
    • (1974) Theoretical Aspects of Aging , pp. 11-21
    • Wilson, D.L.1
  • 25
    • 0028950419 scopus 로고
    • Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing
    • Wong A., Boutis P., Hekimi S. Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing. Genetics. 139:1995;1247-1258.
    • (1995) Genetics , vol.139 , pp. 1247-1258
    • Wong, A.1    Boutis, P.2    Hekimi, S.3
  • 26
    • 0002649560 scopus 로고
    • Introduction to C. elegans biology
    • W.B. et al. Wood. New York: Cold Spring Harbor Laboratory
    • Wood W.B. Introduction to C. elegans biology. Wood W.B. et al. The Nematode Caenorhabditis elegans. 1988;1-16 Cold Spring Harbor Laboratory, New York.
    • (1988) The Nematode Caenorhabditis Elegans , pp. 1-16
    • Wood, W.B.1
  • 27
    • 0032936317 scopus 로고    scopus 로고
    • Characterization of a life-extending mutation in age-2, a new aging gene in Caenorhabditis elegans
    • Yang Y., Wilson D.L. Characterization of a life-extending mutation in age-2, a new aging gene in Caenorhabditis elegans. J. Gerontol. 54A(4):1999;B137-B142.
    • (1999) J. Gerontol. , vol.54 , Issue.4
    • Yang, Y.1    Wilson, D.L.2
  • 28
    • 0342660891 scopus 로고
    • Nematodes as models to study aging
    • Zuckerman B.M. New York: Academic Press
    • Zuckerman B.M., Himmelhoch S. Nematodes as models to study aging. Zuckerman B.M. Nematodes as Biological Models. 2:1980;3-28 Academic Press, New York.
    • (1980) Nematodes As Biological Models , vol.2 , pp. 3-28
    • Zuckerman, B.M.1    Himmelhoch, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.