Kinetic analysis of P-glycoprotein-mediated transport by using normal human placental brush-border membrane vesicles

Pharmaceutical Research

Volumn 20, Issue 1, 2003, Pages 38-44

  Ushigome, Fumihiko ^a   Koyabu, Noriko ^a   Satoh, Shoji ^b   Tsukimori, Kiyomi ^b   Nakano, Hitoo ^b   Nakamura, Takanori ^b   Uchiumi, Takeshi ^b   Kuwano, Michihiko ^b   Ohtani, Hisakazu ^a   Sawada, Yasufumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Blood placental barrier; Brush border membrane vesicles; Digoxin; P glycoprotein; Vinblastine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLOSPORIN A; DIGOXIN; GLYCOPROTEIN P; PROGESTERONE; VERAPAMIL; VINBLASTINE;

ARTICLE; BRUSH BORDER VESICLE; CONTROLLED STUDY; DRUG DISPOSITION; DRUG EXCRETION; DRUG TRANSPORT; FEMALE; GENETIC TRANSFECTION; GENOTYPE; HUMAN; HUMAN TISSUE; INHIBITION KINETICS; MICHAELIS CONSTANT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSPORT KINETICS;

BIOLOGICAL TRANSPORT; CELL MEMBRANE; FEMALE; HUMANS; MICROVILLI; P-GLYCOPROTEIN; PLACENTA; PREGNANCY;

EID: 0037255307     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022290523347     Document Type: Article

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