Brain ischemia as a potential target of gene therapy

Experimental Gerontology

Volumn 38, Issue 1-2, 2003, Pages 183-187

  Ooboshi, Hiroaki ^a   Ibayashi, Setsuro ^a   Takada, Junichi ^a   Kumai, Yasuhiro ^a   Iida, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Aging; Brain; Gene therapy; Gene transfer; Ischemia; Stroke

Indexed keywords

ADENOVIRUS VECTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUCOSE TRANSPORTER; HEAT SHOCK PROTEIN 72; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; LENTIVIRUS VECTOR; LIPOSOME; NEUROPROTECTIVE AGENT; PROTEIN BCL 2; RETROVIRUS VECTOR; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR;

AGED; BRAIN BLOOD VESSEL; BRAIN ISCHEMIA; CONFERENCE PAPER; DISEASE PREDISPOSITION; DNA TRANSFER; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HERPES SIMPLEX VIRUS; HUMAN; NEUROPROTECTION; NONHUMAN; PARAINFLUENZA VIRUS 1; PRIORITY JOURNAL; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; AGING; ANIMALS; BRAIN; BRAIN ISCHEMIA; CEREBRAL ARTERIES; CEREBROVASCULAR ACCIDENT; CYTOKINES; FORECASTING; GENE THERAPY; GENETIC VECTORS; GROWTH SUBSTANCES; HUMANS; HYPOTHERMIA, INDUCED; RECEPTORS, INTERLEUKIN-1;

EID: 0037240863     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(02)00150-X     Document Type: Conference Paper

References (54)

1. Abbott A. Genetic medicine gets real. Nature. 411:2001;410-412.
2. Benveniste H., Drejer J., Schousboe A., Diemer N.H. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1374.
3. Betz A.L., Yang G.Y., Davidson B.L. Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J. Cereb. Blood Flow Metab. 15:1995;547-551.
4. Busto R., Dietrich W.D., Globus M.Y.-T., Valdés I., Sheinberg P., Ginsberg M.D. Small differences in intra-ischemic brain temperature critically determine the extent of ischemic neuronal injury. J. Cereb. Blood Flow Metab. 7:1987;729-738.
5. Christenson S.D., Lake K.D., Ooboshi H., Faraci F.M., Davidson B.L., Heistad D.D. Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue in mice. Stroke. 29:1998;1411-1416.
6. Futrell N., Garcia J.H., Peterson E., Millikan C. Embolic stroke in aged rats. Stroke. 22:1991;1582-1591.
7. Globus M.Y.-T., Busto R., Martinez E., Valdés I., Dietrich W.D., Ginsberg M.D. Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine, and (γ-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat. J. Neurochem. 57:1991;470-478.
8. Hayashi K., Morishita R., Nakagami H., Yoshimura S., Hara A., Matsumoto K., Nakamura T., Ogihara T., Kaneda Y., Sakai N. Gene therapy for preventing neruonal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. Gene Ther. 8:2001;1167-1173.
9. Heistad D.D., Faraci F.M. Gene therapy for cerebral vascular disease. Stroke. 27:1996;1688-1693.
10. Isner J.M. Myocardial gene therapy. Nature. 415:2002;234-239.
11. Isner J.M., Vale P.R., Symes J.F., Losordo D.W. Assessment of risks associated with cardiovascular gene therapy in human subjects. Circ. Res. 89:2001;389-400.
12. Kirino T. Delayed neuronal death in the gerbil following ischemia. Brain Res. 239:1982;57-69.
13. Khurana V.G., Smith L.A., Baker T.A., Eguchi D., O'Brien T., Katusic Z.S. Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm. Stroke. 33:2002;782-789.
14. Kitagawa H., Sasaki C., Sakai K., Mori A., Mitsumoto Y., Mori T., Fukuchi Y., Setoguchi Y., Abe K. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury after transient middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 19:1999;1336-1344.
15. Lawrence M.S., Sun G.G., Kunis D.M., Saydam T.C., Dash R., Ho D.Y., Sapolsky R.M., Steinberg G.K. Overexpression of the glucose transporter gene with a herpes simplex viral vector protects striatal neurons against stroke. J. Cereb. Blood Flow Metab. 16:1996;181-185.
16. Linnik M.D., Zahos P., Geschwind M.D., Federoff H.J. Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke. 26:1995;1670-1674.
17. Mies G., Kohno K., Hossmann K.A. MK-801, a glutamate antagonist, lowers flow threshold for inhibition of protein synthesis after middle cerebral artery occlusion of rat. Neurosci. Lett. 155:1993;65-68.
18. Millikan C. Animal stroke model. Stroke. 23:1992;795-797.
19. Minamisawa H., Smith M.L., Siesjö B.K. The effect of mild hypothermia and hypothermia on brain damage following 5 10, and 15 minutes of forebrain ischemia. Ann. Neurol. 28:1990;26-33.
20. Muhonen M.G., Ooboshi H., Welsh M.J., Davidson B.L., Heistad D.D. Gene transfer to cerebral blood vessels after subarachnoid hemorrhage. Stroke. 28:1997;822-829.
21. Nabel E.G., Plautz G., Nabel G.J. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science. 249:1990;1285-1288.
22. Ono S., Date I., Onoda K., Shiota T., Ohmoto T., Ninomiya Y., Asari S., Morishita R. Decoy administration of NF-kappaB into the subarachnoid space for cerebral angiopathy. Hum. Gene Ther. 9:1998;1003-1011.
23. Ooboshi H., Sadoshima S., Yao H., Ibayashi S., Matsumoto T., Uchimura H., Fujishima M. Ischemia-induced release of amino acids in the hippocampus of aged hypertensive rats. J. Cereb. Blood Flow Metab. 15:1995;227-234.
24. Ooboshi H., Welsh M.J., Rios C.D., Davidson B.L., Heistad D.D. Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue. Circ. Res. 77:1995;7-13.
25. Ooboshi H., Rios C.D., Chu Y., Christenson S.D., Faraci F.M., Davidson B.L., Heistad D.D. Augmented adenovirus-mediated gene transfer to atherosclerotic vessels. Arterioscler. Thromb. Vasc. Biol. 17:1997;1786-1792.
26. Ooboshi H., Rios C.D., Chu Y., Faraci F.M., Davidson B.L., Heistad D.D. Altered vascular function following adenovirus-mediated overexpression of endothelial nitric oxide synthase. Am. J. Physiol. 273:1997;H265-H270.
27. Ooboshi H., Rios C.D., Heistad D.D. Novel methods for adenovirus-mediated gene transfer to blood vessels in vivo. Mol. Cell. Biochem. 172:1997;37-46.
28. Ooboshi H., Toyoda K., Faraci F.M., Lang M.G., Heistad D.D. Improvement of relaxation in an atherosclerotic artery by gene transfer of endothelial nitric oxide synthase. Arterioscler. Thromb. Vasc. Biol. 18:1998;1752-1758.
29. Ooboshi H., Ibayashi S., Takada J., Yao H., Kitazono T., Fujishima M. Adenovirus-mediated gene transfer to ischemic brain. Ischemic flow threshold for transgene expression. Stroke. 32:2001;1043-1047.
30. Pang L., Ye W., Che X.M., Roessler B.J., Betz A.L., Yang G.Y. Reduction of inflammatory response in the mouse brain with adenoviral-mediated transforming growth factor-ss1 expression. Stroke. 32:2001;544-552.
31. Pulsinelli W.A., Brierley J.B., Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11:1982;491-498.
32. Rios C.D., Ooboshi H., Piegors D., Davidson B.L., Heistad D.D. Adenovirus-mediated gene transfer to normal and atherosclerotic arteries. A novel approach. Arterioscler. Thromb. Vasc. Biol. 15:1995;2241-2245.
33. Schneider M.D., French B.A. The advent of adenovirus. Gene therapy for cardiovascular disease. Circulation. 88:1993;1937-1942.
34. Shimazaki K., Urabe M., Monahan J., Ozawa K., Kawai N. Adeno-associated virus vector-mediated bcl-2 gene transfer into post-ischemic gerbil brain in vivo: prospects for gene therapy of ischemia-induced neuronal death. Gene Ther. 7:2000;1244-1249.
35. Shurr A., Tseng M.T., West C.A., Rigor B.M. Taurine improves the recovery of neuronal function following cerebral hypoxia: an in vitro study. Life Sci. 40:1987;2059-2066.
36. Toyoda K., Ooboshi H., Chu Y., Fasbender A.J., Faraci F.M., Davidson B.L., Heistad D.D. Cationic molecules enhance adenovirus-mediated gene transfer to the carotid artery. Stroke. 29:1998;2181-2187.
37. Toyoda K., Faraci F.M., Watanabe Y., Ueda T., Andresen J.J., Chu Y., Otake S., Heistad D.D. Gene transfer of calcitonin gene-related peptide prevents vasoconstriction after subarachnoid hemorrhage. Circ. Res. 87:2000;818-824.
38. Trapnell B.C. Adenoviral vectors for gene transfer. Adv. Drug Deliv. Rev. 12:1993;185-199.
39. Ueda K., Hasuo Y., Ohmura T., Kiyohara Y., Kawano H., Kato I., Shinkawa A., Iwamoto H., Nakayama K., Omae T., Fujishima M. Causes of death in the elderly and their changing pattern in Hisayama, a Japanese community. Results from a long-term and autopsy-based study. J. Am. Geriatr. Soc. 38:1990;1332-1338.
40. Ueda K., Kawano H., Hasuo Y., Fujishima M. Prevalence and etiology of dementia in a Japanese community. Stroke. 23:1992;798-803.
41. Verma I.M., Somia N. Gene therapy - promises, problems and prospects. Nature. 389:1997;239-242.
42. Watanabe Y., Chu Y., Andresen J.J., Nakane H., Faraci F.M., Heistad D.D. Gene transfer of extracellular superoxide dismutase reduces vasospasm following subarachnoid hemorrhage. Stroke. 33:2002;375.
43. Wolf P.A., Kannel W.B., D'Agostino R.B. Ginsberg M.D., Bogousslavsky J. Cerebrovascular Disease: Pathophysiology, Diagnosis, and Management. Cerebrovascular Disease: Pathophysiology, Diagnosis, and Management. 1998;834-849 Blackwell Science, Malden.
44. Xie Y., Mies G., Hossmann K.A. Ischemic threshold of brain protein synthesis after unilateral carotid artery occlusion in gerbils. Stroke. 20:1989;620-626.
45. Xu D.G., Crocker S.J., Doucet J.P., St-Jean M., Tamai K., Hakim A.M., Ikeda J.E., Liston P., Thompson C.S., Korneluk R.G., MacKenzi A., Robertson G.S. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat. Med. 3:1997;997-1004.
46. Yagi T., Jikihara I., Fukumura M., Watabe K., Ohashi T., Eto Y., Hara M., Maeda M. Rescue of ischemic brain injury by adenoviral gene transfer of glial cell line-derived neurotrophic factor after transient global ischemia in gerbils. Brain Res. 885:2000;273-282.
47. Yang G.Y., Mao Y., Zhou L.F., Gong C., Ge H.L., Betz A.L. Expression of intercellular adhesion molecule 1(ICAM-1) is reduced in permanent focal cerebral ischemic mouse brain using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist. Mol. Brain Res. 65:1999;143-150.
48. Yang G.Y., Pang L., Ge H.L., Tan M., Ye W., Liu X.H., Huang F.P., Wu D.C., Che X.M., Song Y., Wen R., Sun Y. Attenuation of ischemia-induced mouse brain injury by SAG, a redox-inducible antioxidant protein. J. Cereb. Blood Flow Metab. 21:2001;722-733.
49. Yao H., Sadoshima S., Ooboshi H., Sato Y., Uchimura H., Fujishima M. Age-related vulnerability to cerebral ischemia in spontaneously hypertensive rats. Stroke. 22:1991;1414-1418.
50. Yao H., Ooboshi H., Ibayashi S., Uchimura H., Fujishima M. Cerebral blood flow and ischemia-induced neurotransmitter release in the striatum of aged spontaneously hypertensive rats. Stroke. 24:1993;577-580.
51. Yao H., Ibayashi S., Sugimori H., Fujii K., Fujishima M. Simplified model of krypton laser-induced thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats. Stroke. 27:1996;333-336.
52. Yenari M.A., Fink S.L., Sun G.H., Chang L.K., Patel M.K., Kunis D.M., Onley D., Ho D.Y., Sapolsky R.M., Steinberg G.K. Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy. Ann. Neurol. 44:1998;584-591.
53. Yenari M.A., Minami M., Sun G.H., Meier T.J., Kunis D.M., McLaughlin J.R., Ho D.Y., Sapolsky R.M., Steinberg G.K. Calbindin d28k overexpression protects striatal neurons from transient focal cerebral ischemia. Stroke. 32:2001;1028-1035.
54. Zabner J., Couture L.A., Gregory R.J., Graham S.M., Smith A.E., Welsh M.J. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell. 75:1993;207-216.