Novel methods for adenovirus-mediated gene transfer to blood vessels in vivo

Molecular and Cellular Biochemistry

Volumn 172, Issue 1-2, 1997, Pages 37-46

  Ooboshi, Hiroaki ^a   David Rios C ^a   Heistad, Donald D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Adenovirus; Blood vessel; Gene expression; Gene transfer

Indexed keywords

BETA GALACTOSIDASE;

ADENOVIRUS; ADVENTITIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BLOOD VESSEL; BRAIN BLOOD VESSEL; CEREBROSPINAL FLUID; CISTERNA MAGNA; CONTROLLED STUDY; FEMORAL ARTERY; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HISTOCHEMISTRY; MALE; MONKEY; NONHUMAN; RAT; REPORTER GENE; SMOOTH MUSCLE FIBER; TRANSGENE;

ADENOVIRIDAE; ANIMALS; CEREBRAL ARTERIES; CISTERNA MAGNA; FEMORAL ARTERY; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HAPLORHINI; MALE; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 8544268684     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006803202179     Document Type: Article

References (56)

1. Nabel EG, Plautz G, Nabel GJ: Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 249: 1285-1288, 1990
2. Lim CS, Chapman GD, Gammon RS, Mublestein JB, Bauman RP, Stack RS, Swain JL: Direct in vivo gene transfer into the coronary and peripheral vasculatures of the intact dog. Circulation 83: 2007-2011, 1991
3. Chapman GD, Lim CS, Gammon RS, Culp SC, Desper JS, Bauman RP, Swain JL, Stack RS: Gene transfer into coronary arteries of intact animals with a percutaneous balloon catheter. Circ Res 71: 27-33, 1992
4. Nabel EG, Plautz G, Nabel GJ: Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis. Proc Natl Sci USA 89: 5157-5161, 1992
5. Leclerc G, Gal D, Takeshita S, Nikol S, Weir L, Isner JM: Percutaneous arterial gene transfer in a rabbit model. Efficiency in normal and balloon-dilated atherosclerotic arteries. J Clin Invest 90: 936-944, 1992
6. Nabel EG, Yang Z, Liptay S, San H, Gordon D, Haudenschild CC, Nabel GJ: Recombinant platelet-derived growth factor B gene expression in porcine arteries induces intimal hyperplasia in vivo. J Clin Invest 91: 1822-1829, 1993
7. Nabel EG, Shum L, Pompili VJ, Yang Z-Y, San H, Shu HB, Liptay S, Gold L, Gordon D, Derynck R, Nabel GJ: Direct transfer of transforming growth factor β1 gene into arteries stimulates fibrocellular hyperplasia. Proc Natl Acad Sci USA 90: 10759-10763, 1993
8. Takeshita S, Gal D, Leclerc G, Pickering JG, Riessen R, Weir L, Isner JM: Increased gene expression after liposome-mediated arterial gene transfer associated with intimal smooth muscle cell proliferation. In vitro and in vivo findings in a rabbit model of vascular injury. J Clin Invest 93: 652-661, 1994
9. Losordo DW, Pickering JG, Takeshita S, Leclerc G, Gal D, Weir L, Kearney M, Jekanowski J, Isner JM: Use of the rabbit ear artery to serially assess foreign protein secretion after site-specific arterial gene transfer in vivo. Evidence that anatomic identification of successful gene transfer may underestimate the potential magnitude of transgene expression. Circulation 89:785-792, 1994
10. Dichek DA, Neville RF, Zwiebel JA, Freeman SM, Leon MB, Anderson WF: Seeding of intravascular stents with genetically engineered endothelial cells. Circulation 80: 1347-1353, 1989
11. Plautz G, Nabel EG, Nabel GJ. Introduction of vascular smooth muscle cells expressing recombinant genes in vivo. Circulation 83: 578-583, 1991
12. Lynch CM, Clowes MM, Osborne WRA, Clowes AW, Miller AD: Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: A model for gene therapy. Proc Natl Acad Sci USA 89:1138-1142, 1992
13. Flugelman MY, Jaklitsch MT, Newman KD, Casscells W, Bratthauer GL, Dichek DA: Low level in vivo gene transfer into the arterial wall through a perforated balloon catheter. Circulation 85:1110-1117, 1992
14. Clowes MM, Lynch CM, Miller AD, Miller DG, Osborne WRA, Clowes AW: Long-term biological response of injured rat carotid ar- tery seeded with smooth muscle cells expressing retrovirally induced human genes. J Clin Invest 93: 644-651, 1994
15. Nabel EG, Pompili VJ, Plautz GE, Nabel GJ: Gene transfer and vascular disease. Cardiovasc Res 28:445-455, 1994
16. Nabel EG, Nabel GJ: Complex models for the study of gene function in cardiovascular biology. Annu Rev Physiol 56: 741-761, 1994
17. Trapnell BC: Adenoviral vectors for gene transfer. Adv Drug Deliv Rev 12: 185-199, 1993
18. Schneider MD, French BA: The advent of adenovirus. Gene therapy for cardiovascular disease. Circulation 88: 1937-1942, 1993
19. Lemarchand P, Jones M, Yamada I, Crystal RG: In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ Res 72: 1132-1138, 1993
20. Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T: Efficient and selective adenovirus-mediated gene transfer into vascular neointima. Circulation 88: 2838-2848, 1993
21. Lee SW, Trapnell BC, Rade JJ, Virmani R, Dichek DA: In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ Res 73: 797-807, 1993
22. Rome JJ, Shayani V, Flugelman MY, Newman KD, Farb A, Virmani R, Dichek D: Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verification with a recombinant adenoviral vector Arterioscler Thromb 14: 148-161, 1994
23. Willard JE, Landau C, Glamann B, Burns D, Jessen ME, Pirwitz MJ, Gerard RD, Meidell RS: Genetic modification of the vessel wall. Comparison of surgical and catheter-based techniques for delivery of recombinant adenovirus. Circulation 89: 2190-2197, 1994
24. Rome JJ, Shayani V, Newman KD, Farrell S, Lee SW, Virmani R, Dichek DA: Adenoviral vector-mediated gene transfer into sheep arteries using a double-balloon catheter. Hum Gene Ther 5:1249-1258, 1994
25. Chang MW, Barr E, Seltzer J, Jiang Y-Q, Nabel GJ, Nabel EG, Parmacek MS, Leiden JF: Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product. Science 267: 518-522, 1995
26. Schulick AH, Dong G, Newman KD, Virmani R, Dichek DA: Endothelium-specific in vivo gene transfer. Circ Res 77: 475-485, 1995
27. Schulick AH, Newman KD, Virmani R, Dichek DA: In vivo gene transfer into injured carotid arteries: optimization and evaluation of acute toxicity. Circulation 91: 2407-2414, 1995
28. Chang MW, Barr E, Lu, MM, Barton K, Leiden JM: Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J Clin Invest 96: 2260-2268, 1995
29. Barr E, Carroll J, Kalynych AM, Tripathy SK, Kozarsky K, Wilson JM, Leiden JM: Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Ther 1: 51-58, 1994
30. French BA, Mazur W, Ali NM, Geske RS, Finnigan JP, Rodgers GP, Roberts R, Raizner AK: Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis. Circulation 90: 2402-2413, 1994
31. Ohno T, Gordon D, San H, Pompili VJ, Imperiale MJ, Nabel GJ, Nabel EG. Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 265: 781-784, 1994
32. Steg PG, Feldman LJ, Scoazec J-Y, Tahlil O, Barry JJ, Boulechfar S, Ragot T, Isner JM, Perricaudet M: Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector. Circulation 90: 1648-1656, 1994
33. Landau C, Pirwitz MJ, Willard MA, Gerard RD, Meidell RS, Willard JE: Adenoviral mediated gene transfer to atherosclerotic arteries after balloon angioplasty. Am Heart J 129: 1051-1057, 1995
34. Feldman LJ, Steg PG, Zheng LP, Chen D, Kearney M, McGarr SE, Barry JJ, Dedieu J, Perricaudet M, Isner JM: Low-efficiency of percutaneous adenovirus-mediated gene transfer in atherosclerotic rabbit. J Clin Invest 95: 2662-2671, 1995
35. Li J-J, Ueno H, Tomita H, Yamamoto H, Kanegae Y, Saito I, Takeshita A: Adenovirus-mediated arterial gene transfer does not require prior injury for submaximal gene expression. Gene Ther 2: 351-354, 1995
36. Ueno H, Li J-J, Tomita H, Yamamoto H, Pan Y, Kanegae Y, Saito I, Takeshita A: Quantitative analysis of repeat adenovirus-mediated gene transfer into injured canine femoral arteries. Arterioscler Thromb Vasc Biol 15: 2246-2253, 1995
37. Newman KD, Dunn PF, Owens JW, Schulick AH, Virmani R, Sukhova G, Libby P, Dichek DA: Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointima hyperplasia. J Clin Invest 96: 2955-2965, 1995
38. Muller DOOM, Gordon D, San H, Zhiyong Y, Pompili VJ, Nabel GJ, Nabel EG: Catheter-mediated pulmonary vascular gene transfer and expression. Circ Res 75: 1039-1049, 1994
39. Schachtner SK, Rome JJ, Hoyt RF Jr, Newman KD, Virmani R, Dichek DA: In vivo adenovirus-mediated gene transfer via the pulmonary artery of rats. Circ Res 76: 701-709, 1995
40. Lamping KG, Dole WP: Acute hypertension selectively potentiates constrictor responses of large coronary arteries to serotonin by altering endothelial function in vivo. Circ Res 61: 904-913, 1987
41. Rios CD, Ooboshi H, Piegors D, Davidson BL, Heistad DD: Adenovirus-mediated gene transfer to normal and atherosclerotic arteries: a novel approach. Arterioscler Thromb Vasc Biol 15: 2241-2245, 1995
42. Ooboshi H, Welsh MJ, Rios CD, Davidson BL, Heistad DD: Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue. Circ Res 77: 7-13, 1995
43. Rich DP, Couture LA, Cardoza LM, Guiggio VM, Armentano D, Espino PC, Hehir K, Welsh MJ, Smith AK, Gregory RJ: Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Hum Gene Ther 4: 461-476, 1993
44. Zabner J, Couture LA, Smith AK, Welsh MJ: Correction of cAMP-stimulated fluid secretion in cystic fibrosis airway epithelia. Efficiency of adenovirus-mediated gene transfer in vitro. Hum Gene Ther 5: 585-593, 1994
45. Davidson BL, Allen ED, Kozarsky KF, Wilson JM, Roessler BJ: A model system for in vivo gene transfer into the central nervous system using adenoviral vector. Nat Genet 3: 219-223, 1993
46. Davidson BL, Doran SE, Shewach DS, Latta JM, Hartman JW, Roessler BJ: Expression of Escherichia coli β-galactosidase and rat HPRT in the CNS of Macaca mulatta following adenoviral mediated gene transfer. Exp Neurol 125: 258-267, 1994
47. Lal B, Cahan MA, Couraud P-O, Goldstein GW, Laterra J. Development of endogenous β-galactosidase and autofluorescence in rat brain microvessels. Implications for cell tracking and gene transfer studies. J Histochem Cytochem 42: 953-956, 1994
48. Edelman ER, Adams DH, Karnovsky MJ: Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury. Proc Natl Acad Sci 87: 3773-3777, 1990
49. Okada T, Bark DH, Mayberg MR: Localized release of perivascular heparin inhibits intimal proliferation after endothelial injury without systemic anticoagulation. Neurosurgery 25: 892-898, 1989
50. Okada T, Bark DH, Mayberg MR: Local anticoagulation without systemic effect using a polymer heparin delivery system. Stroke 19: 1470-1476, 1988
51. Edelman ER, Nugent MA, Karnovsky MJ: Perivascular and intravenous administration of basic fibroblast growth factor. Vascular and solid organ deposition. Proc Natl Acad Sci 90: 1513-1517, 1993
52. Villa AK, Guzman LA, Chen W, Golomb G, Levy RJ, Topol EJ: Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty. J Clin Invest 93: 1243-1249, 1994
53. Tedgui A, Lever MJ: The interaction of convection and diffusion in the transport of 131-I-albumin within the media of the rabbit thoracic aorta. Circ Res 57: 856-863, 1985
54. Simons M, Edelman ER, DeKeyser J, Langer R, Rosenberg RD: Antisense c-myb oligonucleotides inhibit arterial smooth muscle cell accumulation in vivo. Nature 359: 67-70, 1992
55. Engelhardt JF, Ye X, Doranz B, Wilson JM: Ablation of E2A in recombinant adenovirus improves transgene persistence and decreases inflammatory response in mouse liver. Proc Natl Acad Sci USA 91: 6196-6200, 1994
56. Fang B, Eisensmith RC, Wang H, Kay MA, Cross RE, Landen CN, Gordon G, Bellinger DA, Read MS, Hu PC, Brinkhous KM, Wool SLC: Gene therapy for hemophilia B: Host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression. Hum Gene Ther 6: 1039-1044, 1995