메뉴 건너뛰기




Volumn 2, Issue 1, 2003, Pages 77-90

Non-viral methods of gene transfer to airway epithelium

Author keywords

Airway epithelium; Cystic fibrosis; Non viral gene transfer

Indexed keywords

CYTOKINE; DNA; INTERLEUKIN 6; LIPID; PLASMID DNA; POLYCATION; POLYETHYLENEIMINE; POLYLYSINE;

EID: 0037229439     PISSN: 13889532     EISSN: None     Source Type: Journal    
DOI: 10.1163/156855803762295440     Document Type: Review
Times cited : (3)

References (77)
  • 3
    • 0028168773 scopus 로고
    • Galactosylated histone-mediated gene transfer and expression
    • Chen, J., Stickles, R.J. and Daiscendt, K.A. (1994). Galactosylated histone-mediated gene transfer and expression. Hum. Gene Ther., 5: 429-435.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 429-435
    • Chen, J.1    Stickles, R.J.2    Daiscendt, K.A.3
  • 4
    • 0028618172 scopus 로고
    • Enhanced resistance to nuclease degradation of nucleic acids complexed to asialoglycoproteinpolylysine carriers
    • Chiou, H.C., Tangco, M.V., Levine, S.M., Robertson, D., Kormis, K., Wu, C.H. and Wu, G.Y. (1994). Enhanced resistance to nuclease degradation of nucleic acids complexed to asialoglycoproteinpolylysine carriers. Nucleic Acids Res., 22: 5439-5446.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5439-5446
    • Chiou, H.C.1    Tangco, M.V.2    Levine, S.M.3    Robertson, D.4    Kormis, K.5    Wu, C.H.6    Wu, G.Y.7
  • 5
    • 0036371914 scopus 로고    scopus 로고
    • Side-effects of a systemic injection of linear polyethylenimine-DNA complexes
    • Chollet, P., Favrot, M.C., Hurbin, A. and Coll, J.L. (2002). Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. J. Gene Med., 4: 84-91.
    • (2002) J. Gene Med. , vol.4 , pp. 84-91
    • Chollet, P.1    Favrot, M.C.2    Hurbin, A.3    Coll, J.L.4
  • 6
    • 0027447460 scopus 로고
    • Hepatic gene therapy: Adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes
    • Christiano, R.J., Smith, L.C. and Woo, S.L. (1993). Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes. Proc. Natl. Acad. Sci. USA, 90: 2122-2126.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2122-2126
    • Christiano, R.J.1    Smith, L.C.2    Woo, S.L.3
  • 7
    • 0027233696 scopus 로고
    • Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo
    • Chowdhury, N.R., Wu, C.H., Wu, G.Y., Yerneni, P.C., Bommineni, V.R. and Chowdhury, J.R. (1993). Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. J. Biol. Chem., 268: 11265-11271.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11265-11271
    • Chowdhury, N.R.1    Wu, C.H.2    Wu, G.Y.3    Yerneni, P.C.4    Bommineni, V.R.5    Chowdhury, J.R.6
  • 8
    • 0032966457 scopus 로고    scopus 로고
    • Technology evaluation: Cystic fibrosis therapy
    • Cockett, M.I. (1999). Technology evaluation: cystic fibrosis therapy, Genzyme. Curr. Opin. Mol. Ther., 1: 279-283.
    • (1999) Genzyme. Curr. Opin. Mol. Ther. , vol.1 , pp. 279-283
    • Cockett, M.I.1
  • 9
    • 0036230134 scopus 로고    scopus 로고
    • Role of intracellular cationic liposome-DNA complex dissociation in transfection mediated by cationic lipids
    • Cornelis, S., Vandenbranden, M., Ruysschaert, J.M. and Elouahabi, A. (2002). Role of intracellular cationic liposome-DNA complex dissociation in transfection mediated by cationic lipids. DNA Cell Biol., 21: 91-97.
    • (2002) DNA Cell Biol. , vol.21 , pp. 91-97
    • Cornelis, S.1    Vandenbranden, M.2    Ruysschaert, J.M.3    Elouahabi, A.4
  • 10
    • 0027215910 scopus 로고
    • Chicken adenovirus (CELO) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants
    • Cotten, M., Wagner, E., Zatloukal, K. and Bimstiel, M.L. (1993). Chicken adenovirus (CELO) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. J. Virol., 67: 3777-3785.
    • (1993) J. Virol. , vol.67 , pp. 3777-3785
    • Cotten, M.1    Wagner, E.2    Zatloukal, K.3    Bimstiel, M.L.4
  • 11
    • 0028466386 scopus 로고
    • Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus
    • Cotten, M., Baker, A., Saltik, M., Wagner, E. and Buschle, M. (1994). Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus. Gene Ther., 1: 239-246.
    • (1994) Gene Ther. , vol.1 , pp. 239-246
    • Cotten, M.1    Baker, A.2    Saltik, M.3    Wagner, E.4    Buschle, M.5
  • 12
    • 0029815814 scopus 로고    scopus 로고
    • Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation
    • Crook, K., McLachlan, G., Stevenson, B.J. and Porteous, D.J. (1996). Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation. Gene Ther., 3: 834-839.
    • (1996) Gene Ther. , vol.3 , pp. 834-839
    • Crook, K.1    McLachlan, G.2    Stevenson, B.J.3    Porteous, D.J.4
  • 13
    • 0030003605 scopus 로고    scopus 로고
    • Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte derived macrophages
    • Erbacher, P., Bousser, M.T., Raimond, J., Monsigny, M., Midoux, P. and Roche, A.C. (1996). Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte derived macrophages. Hum. Gene Ther., 7: 721-729.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 721-729
    • Erbacher, P.1    Bousser, M.T.2    Raimond, J.3    Monsigny, M.4    Midoux, P.5    Roche, A.C.6
  • 16
    • 0027365343 scopus 로고
    • Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor
    • Ferkol, T., Kaetzel, C.S. and Davis, P.B. (1993). Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor. J. Clin. Invest., 92: 2394-2400.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2394-2400
    • Ferkol, T.1    Kaetzel, C.S.2    Davis, P.B.3
  • 17
    • 0028799484 scopus 로고
    • Gene transfer into airways in animals by targeting the polymeric immunoglobulin receptor
    • Ferkol, T., Perales, J.C., Kaetzel, C.S., Eckman, E., Hanson, R.W. and Davis, P.B. (1995). Gene transfer into airways in animals by targeting the polymeric immunoglobulin receptor. J. Clin. Invest., 95, 493-502.
    • (1995) J. Clin. Invest. , vol.95 , pp. 493-502
    • Ferkol, T.1    Perales, J.C.2    Kaetzel, C.S.3    Eckman, E.4    Hanson, R.W.5    Davis, P.B.6
  • 18
    • 0030071910 scopus 로고    scopus 로고
    • Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes
    • Friend, D.S., Papahadjopoulos, D. and Debs, R.J. (1996). Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim. Biophys. Acta, 1278: 41-50.
    • (1996) Biochim. Biophys. Acta , vol.1278 , pp. 41-50
    • Friend, D.S.1    Papahadjopoulos, D.2    Debs, R.J.3
  • 20
    • 0035850212 scopus 로고    scopus 로고
    • Evaluation of polyplexes as gene transfer agents
    • Gebhart, C.L. and Kabanov, A.V. (2001). Evaluation of polyplexes as gene transfer agents. J. Control Release, 73: 401-416.
    • (2001) J. Control Release , vol.73 , pp. 401-416
    • Gebhart, C.L.1    Kabanov, A.V.2
  • 23
    • 0032811354 scopus 로고    scopus 로고
    • Poly(ethylenimine) and its role in gene delivery
    • Godbey, W.T., Wu, K.K. and Mikos, A.G. (1999). Poly(ethylenimine) and its role in gene delivery. J. Control Release, 60: 149-160.
    • (1999) J. Control Release , vol.60 , pp. 149-160
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 24
    • 0031023264 scopus 로고    scopus 로고
    • Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery
    • Hong, K., Zheng, W., Baker, A. and Papahadjopoulos, D. (1997). Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery. FEBS Lett., 400: 233-237.
    • (1997) FEBS Lett. , vol.400 , pp. 233-237
    • Hong, K.1    Zheng, W.2    Baker, A.3    Papahadjopoulos, D.4
  • 26
    • 0032551589 scopus 로고    scopus 로고
    • Efficiency of cationic lipid-mediated transfection of polarized and differentiated airway epithelial cells in vitro and in vivo
    • Jiang, C., O'Connor, S.P., Fang, S.L., Wang, K.X., Marshall, J., Williams, J.L., Wilburn, B., Echelard, Y. and Cheng, S.H. (1998). Efficiency of cationic lipid-mediated transfection of polarized and differentiated airway epithelial cells in vitro and in vivo. Hum. Gene Ther., 9: 1531-1542.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1531-1542
    • Jiang, C.1    O'Connor, S.P.2    Fang, S.L.3    Wang, K.X.4    Marshall, J.5    Williams, J.L.6    Wilburn, B.7    Echelard, Y.8    Cheng, S.H.9
  • 27
    • 0021269089 scopus 로고
    • Sequence requirements for nuclear location of simian virus 40 large-T antigen
    • Kalderon, D., Richardson, W.D., Markham, A.F. and Smith, A.E. (1984). Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature, 311: 33-38.
    • (1984) Nature , vol.311 , pp. 33-38
    • Kalderon, D.1    Richardson, W.D.2    Markham, A.F.3    Smith, A.E.4
  • 28
    • 0032531160 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells
    • Kelley, T.J. and Drumm, M.L. (1998). Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. J. Clin. Invest., 102: 1200-1207.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1200-1207
    • Kelley, T.J.1    Drumm, M.L.2
  • 29
    • 17344365059 scopus 로고    scopus 로고
    • A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis
    • Knowles, M.R., Noone, P.G., Hohneker, K., Johnson, L.G., Boucher, R.C., Efthimiou, J., Crawford, C., Brown, R., Schwartzbach, C. and Pearlman, R. (1998). A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis. Hum. Gene Ther., 9: 249-269.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 249-269
    • Knowles, M.R.1    Noone, P.G.2    Hohneker, K.3    Johnson, L.G.4    Boucher, R.C.5    Efthimiou, J.6    Crawford, C.7    Brown, R.8    Schwartzbach, C.9    Pearlman, R.10
  • 30
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg, A.M. (2002). CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol., 20: 709-760.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 32
    • 0030866645 scopus 로고    scopus 로고
    • In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes
    • Li, S. and Huang, L. (1997). In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther., 4: 891-900.
    • (1997) Gene Ther. , vol.4 , pp. 891-900
    • Li, S.1    Huang, L.2
  • 33
    • 0036463410 scopus 로고    scopus 로고
    • Applications of muscle electroporation gene therapy
    • Li, S. and Benninger, M. (2002). Applications of muscle electroporation gene therapy. Curr. Gene Ther., 2: 01-105.
    • (2002) Curr. Gene Ther. , vol.2 , pp. 01-105
    • Li, S.1    Benninger, M.2
  • 34
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu, F., Song, Y. and Liu, D. (1999). Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther., 6: 1258-1266.
    • (1999) Gene Ther. , vol.6 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 35
    • 0037122695 scopus 로고    scopus 로고
    • Development of non-viral vectors for systemic gene delivery
    • Liu, F. and Huang, L. (2002a). Development of non-viral vectors for systemic gene delivery. J. Control. Release, 78: 259-266.
    • (2002) J. Control. Release , vol.78 , pp. 259-266
    • Liu, F.1    Huang, L.2
  • 36
    • 0036056326 scopus 로고    scopus 로고
    • Electric gene transfer to the liver following systemic administration of plasmid DNA
    • Liu, F. and Huang, L. (2002b). Electric gene transfer to the liver following systemic administration of plasmid DNA. Gene Ther., 9: 1116-1119.
    • (2002) Gene Ther. , vol.9 , pp. 1116-1119
    • Liu, F.1    Huang, L.2
  • 39
    • 0033579358 scopus 로고    scopus 로고
    • Gene therapy death prompts review of adenovirus vector
    • Marshall, E. (1999). Gene therapy death prompts review of adenovirus vector. Science, 286: 2244-2245.
    • (1999) Science , vol.286 , pp. 2244-2245
    • Marshall, E.1
  • 41
    • 0028414109 scopus 로고
    • Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes
    • Monsigny, M., Roche, A.C., Midoux, P. and Mayer, R. (1994). Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes. Adv. Drug. Delivery Rev., 14: 1-24.
    • (1994) Adv. Drug. Delivery Rev. , vol.14 , pp. 1-24
    • Monsigny, M.1    Roche, A.C.2    Midoux, P.3    Mayer, R.4
  • 42
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris, M., Brunner, S., Schuller, S., Kircheis, R. and Wagner, E. (1999). PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther., 6: 595-605.
    • (1999) Gene Ther. , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 45
    • 0028223310 scopus 로고
    • Gene transfer in vivo: Sustained expression and regulation of genes introduced into the livers by receptor targeted uptake
    • Perales, J.C., Ferkol, T., Beegen, H., Ratnoff, O.D. and Hanson, R.W. (1994a). Gene transfer in vivo: Sustained expression and regulation of genes introduced into the livers by receptor targeted uptake. Proc. Natl. Acad. Sci. USA, 91: 4086-4090.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4086-4090
    • Perales, J.C.1    Ferkol, T.2    Beegen, H.3    Ratnoff, O.D.4    Hanson, R.W.5
  • 46
    • 0028079888 scopus 로고
    • An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes
    • Perales, J.C., Ferkol, T., Molas, M. and Hanson, R.W. (1994b). An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes. Eur. J. Biochem., 226: 255-266.
    • (1994) Eur. J. Biochem. , vol.226 , pp. 255-266
    • Perales, J.C.1    Ferkol, T.2    Molas, M.3    Hanson, R.W.4
  • 47
    • 0037125986 scopus 로고    scopus 로고
    • A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19
    • Philpott, N.J., Gomos, J., Berns, K.I. and Falck-Pedersen, E. (2002b). A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19. Proc. Natl. Acad. Sci. USA, 99: 12381-12385.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12381-12385
    • Philpott, N.J.1    Gomos, J.2    Berns, K.I.3    Falck-Pedersen, E.4
  • 48
    • 0028199067 scopus 로고
    • The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems
    • Plank, C., Oberhauser, B., Mechtler, K., Koch, C. and Wagner, E. (1994). The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J. Biol. Chem., 269: 12918-12924.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12918-12924
    • Plank, C.1    Oberhauser, B.2    Mechtler, K.3    Koch, C.4    Wagner, E.5
  • 49
    • 0029789793 scopus 로고    scopus 로고
    • Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery
    • Plank, C., Mechtler, K., Szoka, F. and Wagner, E. (1996). Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum. Gene Ther., 7: 1437-1446.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1437-1446
    • Plank, C.1    Mechtler, K.2    Szoka, F.3    Wagner, E.4
  • 50
    • 0033585470 scopus 로고    scopus 로고
    • Branched cationic peptides for gene delivery: Role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes
    • Plank, C., Tang, M.X., Wolfe, A.R. and Szoka, F.C. Jr. (1999). Branched cationic peptides for gene delivery: role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes. Hum. Gene Ther., 10: 319-332.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 319-332
    • Plank, C.1    Tang, M.X.2    Wolfe, A.R.3    Szoka F.C., Jr.4
  • 51
    • 0032571392 scopus 로고    scopus 로고
    • Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
    • Pollard, H., Remy, J.S., Loussouarn, G., Demolombe, S., Behr, J.P. and Escande, D. (1998). Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J. Biol. Chem., 273: 7507-7511.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7507-7511
    • Pollard, H.1    Remy, J.S.2    Loussouarn, G.3    Demolombe, S.4    Behr, J.P.5    Escande, D.6
  • 52
    • 25944457259 scopus 로고    scopus 로고
    • Sec-R targeted molecular conjugate-DNA complexes can be re-administered with no loss of efficacy of future doses
    • Quan, W., Ziady, A.G. and Davis, P.B. (2001). Sec-R targeted molecular conjugate-DNA complexes can be re-administered with no loss of efficacy of future doses. Pediatr. Pulmonol., 17: S254.
    • (2001) Pediatr. Pulmonol. , vol.17
    • Quan, W.1    Ziady, A.G.2    Davis, P.B.3
  • 53
    • 0034219238 scopus 로고    scopus 로고
    • In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers
    • Rudolph, C., Lausier, J., Naundorf, S., Muller, R.H. and Rosenecker, J. (2000). In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers. J. Gene Med., 2: 269-278.
    • (2000) J. Gene Med. , vol.2 , pp. 269-278
    • Rudolph, C.1    Lausier, J.2    Naundorf, S.3    Muller, R.H.4    Rosenecker, J.5
  • 57
    • 0037103750 scopus 로고    scopus 로고
    • Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions
    • Shi, F., Wasungu, L., Nomden, A., Stuart, M.C., Polushkin, E., Engberts, J.B. and Hoekstra, D. (2002). Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions. Biochem. J., 366: 333-341.
    • (2002) Biochem. J. , vol.366 , pp. 333-341
    • Shi, F.1    Wasungu, L.2    Nomden, A.3    Stuart, M.C.4    Polushkin, E.5    Engberts, J.B.6    Hoekstra, D.7
  • 59
    • 0033544842 scopus 로고    scopus 로고
    • Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium
    • Tio, R.A., Tkebuchava, T., Scheuermann, T.H., Lebherz, C., Magner, M., Kearny, M., Esakof, D.D., Isner, J.M. and Symes, J.F. (1999). Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium. Hum. Gene Ther., 10: 2953-2960.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2953-2960
    • Tio, R.A.1    Tkebuchava, T.2    Scheuermann, T.H.3    Lebherz, C.4    Magner, M.5    Kearny, M.6    Esakof, D.D.7    Isner, J.M.8    Symes, J.F.9
  • 60
    • 0034924240 scopus 로고    scopus 로고
    • Effects of linear polyethylenimine and polyethylenimine/DNA on lung function after airway instillation to rat lungs
    • Uduehi, A.N., Stammberger, U., Kubisa, B., Gugger, M., Buehler, T.A., and Schmid, R.A. (2001). Effects of linear polyethylenimine and polyethylenimine/DNA on lung function after airway instillation to rat lungs. Mol. Ther., 4: 52-57.
    • (2001) Mol. Ther. , vol.4 , pp. 52-57
    • Uduehi, A.N.1    Stammberger, U.2    Kubisa, B.3    Gugger, M.4    Buehler, T.A.5    Schmid, R.A.6
  • 61
    • 0026502766 scopus 로고
    • Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low-density lipoprotein receptor-deficient rabbits
    • Wilson, J.M., Grossman, M., Wu, C.H., Chowdhury, N.R., Wu, G.Y. and Chowdhury, J.R. (1992). Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low-density lipoprotein receptor-deficient rabbits. J. Biol. Chem., 267: 963-967.
    • (1992) J. Biol. Chem. , vol.267 , pp. 963-967
    • Wilson, J.M.1    Grossman, M.2    Wu, C.H.3    Chowdhury, N.R.4    Wu, G.Y.5    Chowdhury, J.R.6
  • 62
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
    • Wu, G.Y. and Wu, C.H. (1987). Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J. Biol. Chem., 262: 4429-4432.
    • (1987) J. Biol. Chem. , vol.262 , pp. 4429-4432
    • Wu, G.Y.1    Wu, C.H.2
  • 63
    • 0023811723 scopus 로고
    • Receptor-mediated gene delivery and expression in vivo
    • Wu, G.Y. and Wu, C.H. (1988). Receptor-mediated gene delivery and expression in vivo. J. Biol. Chem., 263: 14621-14624.
    • (1988) J. Biol. Chem. , vol.263 , pp. 14621-14624
    • Wu, G.Y.1    Wu, C.H.2
  • 65
    • 0034149827 scopus 로고    scopus 로고
    • Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
    • Yew, N.S., Zhao, H., Wu, I.H., Song, A., Tousignant, J.D., Przybylska, M. and Cheng, S.H. (2000). Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol. Ther., 1(3): 255-262.
    • (2000) Mol. Ther. , vol.1 , Issue.3 , pp. 255-262
    • Yew, N.S.1    Zhao, H.2    Wu, I.H.3    Song, A.4    Tousignant, J.D.5    Przybylska, M.6    Cheng, S.H.7
  • 66
    • 0035989006 scopus 로고    scopus 로고
    • CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo
    • Yew, N.S., Zhao, H., Przybylska, M., Wu, I.H., Tousignant, J.D., Scheule, R.K. and Cheng S.H. (2002). CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo. Mol. Ther., 5: 731-738.
    • (2002) Mol. Ther. , vol.5 , pp. 731-738
    • Yew, N.S.1    Zhao, H.2    Przybylska, M.3    Wu, I.H.4    Tousignant, J.D.5    Scheule, R.K.6    Cheng, S.H.7
  • 70
    • 0035988755 scopus 로고    scopus 로고
    • Receptor-directed molecular conjugates for gene transfer
    • J. Morgan (Ed.), Humana Press Inc., Totowa, NJ
    • Ziady, A.G. and Davis, P.B. (2001). Receptor-directed molecular conjugates for gene transfer. in: Methods in Molecular Medicine: Gene Therapy Protocols, vol. 69, J. Morgan (Ed.), Humana Press Inc., Totowa, NJ, pp. 25-48.
    • (2001) Methods in Molecular Medicine: Gene Therapy Protocols , vol.69 , pp. 25-48
    • Ziady, A.G.1    Davis, P.B.2
  • 71
    • 0012417087 scopus 로고    scopus 로고
    • Molecular conjugates
    • D.T. Curiel and J.T. Douglas (Eds.), John Wiley and Sons, Indianapolis, IN
    • Ziady, A.G. and Davis, P.B. (2002). Molecular conjugates. In: Vector Targeting for Therapeutic Gene Delivery, D.T. Curiel and J.T. Douglas (Eds.), John Wiley and Sons, Indianapolis, IN, pp. 63-86.
    • (2002) Vector Targeting for Therapeutic Gene Delivery , pp. 63-86
    • Ziady, A.G.1    Davis, P.B.2
  • 73
    • 0032416587 scopus 로고    scopus 로고
    • Ligand substitution of receptor targeted DNA complexes affects gene transfer into hepatoma cells
    • Ziady, A.G., Ferkol, T., Gerken, T., Dawson, D.V., Perlmutter, D.H. and Davis, P.B. (1998). Ligand substitution of receptor targeted DNA complexes affects gene transfer into hepatoma cells. Gene Ther., 5: 1685-1697.
    • (1998) Gene Ther. , vol.5 , pp. 1685-1697
    • Ziady, A.G.1    Ferkol, T.2    Gerken, T.3    Dawson, D.V.4    Perlmutter, D.H.5    Davis, P.B.6
  • 74
    • 0033582456 scopus 로고    scopus 로고
    • Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo
    • Ziady, A.G., Ferkol, T., Dawson, D.V., Perlmutter, D.H. and Davis, P.B. (1999). Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo. J. Biol. Chem., 274: 4908-4916.
    • (1999) J. Biol. Chem. , vol.274 , pp. 4908-4916
    • Ziady, A.G.1    Ferkol, T.2    Dawson, D.V.3    Perlmutter, D.H.4    Davis, P.B.5
  • 75
    • 0036222250 scopus 로고    scopus 로고
    • Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor
    • Ziady, A.G., Kelley, T.J., Milliken, E., Ferkol, T. and Davis, P.B. (2002a). Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor. Mol. Ther., 5: 413-419.
    • (2002) Mol. Ther. , vol.5 , pp. 413-419
    • Ziady, A.G.1    Kelley, T.J.2    Milliken, E.3    Ferkol, T.4    Davis, P.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.