Extracellular matrix enhances heregulin-dependent BRCA1 phosphorylation and suppresses BRCA1 expression through its C terminus

Molecular and Cellular Biology

Volumn 23, Issue 2, 2003, Pages 579-593

  Miralem, Tiho ^a   Avraham, Hava Karsenty ^a  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; BRCA1 PROTEIN; CALPASTATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; INTEGRIN; LACTACYSTIN; LAMININ; MESSENGER RNA; N BENZYLOXYCARBONYLISOLEUCYLGLUTAMYL (O TERT BUTYL)ALANYLLEUCINE; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; POLYLYSINE; PROTEIN; PROTEIN KINASE B; THYMIDINE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEADY STATE; WESTERN BLOTTING; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLCYSTEINE; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRCA1 PROTEIN; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; COLLAGEN; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASES; CYSTEINE PROTEINASE INHIBITORS; DOWN-REGULATION; DRUG COMBINATIONS; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; GENETIC VECTORS; GERM-LINE MUTATION; HUMANS; IMMUNOBLOTTING; LAMININ; LEUPEPTINS; MAP KINASE SIGNALING SYSTEM; NEUREGULIN-1; PHENOTYPE; PHOSPHORYLATION; POLYLYSINE; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS; RECEPTOR, ERBB-2; RNA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037218809     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.2.579-593.2003     Document Type: Article

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