Elevated hepatic and depressed renal cytochrome P450 activity in the Tg2576 transgenic mouse model of Alzheimer's disease

Journal of Neurochemistry

Volumn 80, Issue 4, 2002, Pages 571-578

  Van Ess, P J ^a   Pedersen, W A ^b,c   Culmsee, C ^b,c   Mattson, M P ^b,c,d   Blouin, R A ^a  

^a Division of Pharmaceutical Sciences   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Cytochrome P450; Metabolism

Indexed keywords

AMYLOID BETA PROTEIN; CYTOCHROME P450; CYTOCHROME P450 2B; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; CYTOCHROME P450 4A; CYTOCHROME P450 ISOENZYME; CYTOCHROME REDUCTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; DISEASE MODEL; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; KIDNEY; LIVER LEVEL; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; HUMANS; ISOENZYMES; KIDNEY; LIVER; MALE; MICE; MICE, TRANSGENIC; MICROSOMES, LIVER;

ANIMALIA; MUS MUSCULUS; STAPHYLOCOCCUS PHAGE 3A;

EID: 0036329642     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-3042.2001.00724.x     Document Type: Article

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