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Volumn 189, Issue 1-2, 2002, Pages 157-168

Structural determinants in the second intracellular loop of the human follicle-stimulating hormone receptor are involved in Gs protein activation

Author keywords

Follicle stimulating hormone; Follicle stimulating hormone receptor; G protein coupled receptors; G proteins; Intracellular signaling

Indexed keywords

ADENYLATE CYCLASE; CELL SURFACE RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FOLLITROPIN; FOLLITROPIN RECEPTOR; GONADOTROPIN; GONADOTROPIN RECEPTOR; HORMONE RECEPTOR; LUTEINIZING HORMONE RECEPTOR; MUSCARINIC RECEPTOR; RECOMBINANT FOLLITROPIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; SYNTHETIC PEPTIDE; VASOPRESSIN RECEPTOR;

EID: 0037187331     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(01)00720-1     Document Type: Article
Times cited : (37)

References (63)
  • 2
    • 0031475025 scopus 로고    scopus 로고
    • Mutations of the conservewd DRS motif in the second intracellular loop of the gonadotropin-releasing hormone receptor affect expression, activation, and internalization
    • (1997) Mol. Endocrinol. , vol.11 , pp. 1203-1212
    • Arora, K.K.1    Cheng, Z.2    Catt, K.J.3
  • 4
    • 0029081150 scopus 로고
    • Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor
    • (1995) J. Biol. Chem. , vol.270 , pp. 22820-22826
    • Arora, K.K.1    Sakai, A.2    Catt, K.J.3
  • 5
    • 0006316241 scopus 로고    scopus 로고
    • Baldwin, J.M., 1993. The probable arrangement of the helics in G protein-coupled receptors. EMBO J. 12, 1693-1703.
  • 15
    • 0034464742 scopus 로고    scopus 로고
    • Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
    • (2000) Endocr. Rev. , vol.21 , pp. 90-113
    • Gether, U.1
  • 17
    • 0029562311 scopus 로고
    • Synthetic peptides corresponding to residues 551-555 and 650-653 of the rat testicular follicle-stimulating hormone (FSH) receptor are sufficient for post-receptor modulation of Sertoli cell responsiveness to FSH stimulation
    • (1995) Regul. Pept. , vol.60 , pp. 177-183
    • Grasso, P.1    Deziel, M.R.2    Reichert, L.E.3
  • 18
    • 0029033917 scopus 로고
    • A synthetic peptide corresponding to the third cytoplasmic loop (residues 533-555) of the testicular follicle-stimulating hormone receptor affects signal transduction in rat testis membranes and in intact cultured rat Sertoli cells
    • (1995) Mol. Cell. Endocrinol. , vol.110 , pp. 35-41
    • Grasso, P.1    Leng, N.2    Reichert, L.E.3
  • 19
    • 0028909822 scopus 로고
    • A synthetic peptide corresponding to residues 645-653 in the carboxyl terminal cytoplasmic domain of the rat testicular follicle stimulating hormone receptor modulates G protein coupled-receptor signaling in rat testis membranes and in intact cultured rat Sertoli cells
    • (1995) Mol. Cell. Endocrinol. , vol.108 , pp. 43-50
    • Grasso, P.1    Leng, N.2    Reichert, L.E.3
  • 26
    • 0006316244 scopus 로고    scopus 로고
    • Kobilka, B.K., Kobilka, T.S., Daniel, K.W., Regan, J.W., Caron, M.G., Lefkowitz, R.J., 1988. Chimeric α2-, β2- adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity. Science 249, 1310-1316.
  • 33
    • 0033645593 scopus 로고    scopus 로고
    • Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1797-1810
    • Min, L.1    Ascoli, M.2
  • 44
    • 0024581111 scopus 로고
    • The follicle-stimulating hormone (FSH) receptor in testis: interaction with FSH, mechanism of signal transduction, and properties of the purified receptor
    • (1989) Biol. Reprod. , vol.40 , pp. 13-26
    • Reichert, L.E.1    Dattatreyamurty, B.2
  • 50
    • 0031007878 scopus 로고    scopus 로고
    • Modulation of FSH receptor phosphorylation correlates with hormone-induced coupling to the adenylate cyclase system
    • (1997) Endocrine , vol.2 , pp. 179-185
    • Selvaraj, N.1    Amsterdam, A.2
  • 53
    • 0006317876 scopus 로고    scopus 로고
    • Strader, C.D., Fong, T.M., Tota, M.R., Underwood, D., Dixon, R.A.F., 1994. Structure and function of G protein-coupled receptors. Annu. Rev. Biochem. 63, 101-132.
  • 54
    • 0029037694 scopus 로고
    • Expression of a connexin 43/β galactosidase fusion protein inhibits gap functional communication in NIH373 cells
    • (1995) J. Cell. Biol. , vol.130 , pp. 419-429
    • Sullivan, R.1    Lo, C.W.2
  • 55
    • 0006374642 scopus 로고    scopus 로고
    • Timossi, C., Barrios-de-Tomasi, J., González-Suárez, R., Celeste Arranz, M., Padmanabhan, V., Conn, P.M., Ulloa-Aguirre, A., 2000. Differential effects of the charge variants of human follicle-stimulating hormone. J. Endocrinol. 165, 193-205.
  • 56
    • 0003012873 scopus 로고    scopus 로고
    • G protein-coupled receptors and the G protein family
    • Conn P.M. (Ed.), Handbook of Physiology-Endocrinology: Section 7. Cellular Endocrinology, New York: Oxford University Press
    • (1998) , pp. 87-124
    • Ulloa-Aguirre, A.1    Conn, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.