Acylation of β-lactams by class a β-lactamase: An ab initio theoretical study on the effects of the oxy-anion hole

Journal of the American Chemical Society

Volumn 119, Issue 27, 1997, Pages 6423-6431

  Wladkowski, Brian D ^a   Chenoweth, Sarah A ^a   Sanders, Julie N ^a   Krauss, Morris ^a   Stevens, Walter J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE;

ACYLATION; ANION TRANSPORT; ARTICLE; BACTERIAL INFECTION; CATALYSIS; CELL KILLING; CRYSTAL STRUCTURE; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME ISOLATION; HYDROLYSIS; NONHUMAN;

EID: 0030857280     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja963678g     Document Type: Article

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