Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition

Journal of Biological Chemistry

Volumn 277, Issue 43, 2002, Pages 41014-41022

  Guo, Xiao Ling ^a,b,c,d   Shen, Kui ^a,b,c,d   Wang, Fang ^a,b,c,d   Lawrence, David S ^a,b,c,d   Zhang, Zhong Yin ^a,b,c,d  

^a Albert Einstein Compreh Cancer C   (United States)

^b Department of Biochemistry ^*  (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; DISEASES; GENES; PATHOLOGY; PHYSIOLOGY;

MOLECULAR BASIS;

ENZYMES;

PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CELL COMMUNICATION; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; GENETIC CODE; INHIBITION KINETICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SURFACE PROPERTY;

AMINO ACID SEQUENCE; BINDING SITES; ENZYME INHIBITORS; KINETICS; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEIN-TYROSINE-PHOSPHATASE; VANADATES;

EID: 0037174872     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207347200     Document Type: Article

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