Potent and highly selective inhibitors of the protein tyrosine phosphatase 1B

Biochemistry

Volumn 38, Issue 12, 1999, Pages 3793-3803

  Taing, Meng ^a   Keng, Yen Fang ^a   Shen, Kui ^a   Wu, Li ^a   Lawrence, David S ^a   Zhang, Zhong Yin ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIS(ARYLDIFLUOROPHOSPHONATE) DERIVATIVE; INSULIN; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; INSULIN RESISTANCE; PRIORITY JOURNAL;

CATALYTIC DOMAIN; DIPHOSPHONATES; ENZYME INHIBITORS; HUMANS; PROTEIN-TYROSINE-PHOSPHATASE; TYROSINE;

EID: 0033596855     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9813781     Document Type: Article

References (41)

1. Lawrence, D. S., and Niu, J. (1998) Pharmacol. Ther. 77, 81-114.
2. Zhang, Z.-Y. (1998) CRC Crit. Rev. Biochem. Mol. Biol. 33, 1-52.
3. Tonks, N. K., Diltz, C. D., and Fischer, E. H. (1988) J. Biol. Chem. 263, 6722-30.
4. Tonks, N. K., Diltz, C. D., and Fischer, E. H. (1988) J. Biol. Chem. 263, 6731-7.
5. Goldstein, B. J. (1993) Receptor 3, 1-15.
6. Ahmad, F., Li, P. M., Meyerovitch, J., and Goldstein, B. J. (1995) J. Biol. Chem. 270, 20503-8.
7. Kenner, K. A., Anyanwu, E., Olefsky, J. M., and Kusari, J. (1996) J. Biol. Chem. 271, 19810-6.
8. Wiener, J. R., and Kerns, B. J., Harvey, E. L., Conaway, M. R., Iglehart, J. D., Berchuck A., and Bast, R. C., Jr. (1994) J. Natl. Cancer Inst. 86, 372-8.
9. Liu, F., Hill, D. E., and Chernoff, J. (1996) J. Biol. Chem. 271, 31290-95.
10. Liu, F., and Chernoff, J. (1997) Biochem. J. 327, 139-45.
11. Chen, L., Montserat, J., Lawrence, D. S., and Zhang, Z. Y. (1996) Biochemistry 35, 9349-54.
12. Puius, Y. A., Zhao, Y., Sullivan, M., Lawrence, D. S., Almo S. C., and Zhang, Z. Y. (1997) Proc. Natl. Acad. Sci. U S A. 94, 13420-5.
13. Middleton, W. (1975) J. Org. Chem. 40, 574-8.
14. Hengge, A. C., Sowa, G, Wu, L., and Zhang, Z.-Y. (1995) Biochemistry 34, 13982-13987.
15. Guan, K. L., and Dixon, J. E. (1991) Anal. Biochem. 192, 262-267.
16. Pot, D. A., Woodford, T. A., Remboutsika, E., Haun, R. S. and Dixon, J. E. (1991) J. Biol. Chem. 266, 19688-19696.
17. Zhang, Z.-Y., Wu, L., and Chen, L. (1995) Biochemistry 34, 16088-16096.
18. Zhang, Z.-Y., and Van Etten, R. L. (1991) J. Biol. Chem. 266, 1516-1525.
19. Zhang, Z.-Y., Thieme-Sefler, A. M., Maclean, D., Roeske, R., and Dixon, J. E. (1993) Anal. Biochem. 211, 7-15.
20. Ishibashi, T., Bottara, D. P., Chan, A., Miki, T., and Aaronson, S. A. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 12170-12174.
21. Guan, K. L., Broyles, S., and Dixon, J. E. (1991) Nature 350, 359-361.
22. Zhang, W. R., Li, P. M., Oswald, M. A., and Goldstein, B. J. (1996) Mol. Endocrinol. 10, 575-84.
23. Mooney, R. A., Kulas, D. T., Bleyle, L. A., and Novak, J. S. (1997) Biochem. Biophys. Res. Commun. 235, 709-12.
24. Ahmad, F., and Goldstein, B. J. (1997) J. Biol. Chem. 272, 448-57.
25. Lammers, R., Moller, N. P., and Ullrich, A. (1997) FEBS Lett. 404, 37-40.
26. Seely, B. L., Staubs, P. A., Reichart, D. R., Berhanu, P., Milarski, K. L., Saltiel, A. R., Kusari, J., and Olefsky, J. M. (1996) Diabetes 45, 1379-85.
27. Ahmad, F., Azevedo, J. L., Cortright, R., Dohm, G. L., and Goldstein, B. J. (1997) J. Clin. Invest. 100, 449-58.
28. Li, P. M., Zhang, W. R., and Goldstein, B. J. (1996) Cell Signal. 8, 467-73.
29. Burke, T. R. Jr., Kole, H. K., and Roller, P. P. (1994) Biochem. Biophys. Res. Commun. 204, 129-34.
30. Chen, L., Wu, L., Otaka, A., Smyth, M. S., Roller, P. P., Burke, T. R., Jr., den Hertog, J., and Zhang, Z. Y. (1994) Biochem. Biophys. Res. Commun. 216, 976-84.
31. Kole, H. K., Smyth, M. S., Russ, P. L., and Burke, T. R. Jr. (1995) Biochem. J. 311 (Pt 3), 1025-31.
32. Burke, T. R. Jr. Ye, B., Yan, X., Wang, S., Jia, Z., Chen, L., Zhang, Z. Y., and Barford, D. (1996) Biochemistry 35, 15989-96.
33. Moran, E. J., Sarshar, S., Cargill, J. F., Shahbaz, M. M., Lio, A., Mjalli, A. M. M., and Armstrong, R. W. (1995) J. Am. Chem. Soc. 117, 10787-10788.
34. Taylor, W. P., Zhang, Z. Y., and Widlanski, T. S. (1996) Bioorg. Med. Chem. 4, 1515-20.
35. Rice, R. L., Rusnak, J. M., Yokokawa, F., Yokokawa, S., Messner, D. J., Boynton, A. L., Wipf, P., and Lazo, J. S. (1997) Biochemistry 36, 15965-74.
36. Zhang, Z.-Y. (1995) J. Biol. Chem. 270, 11199-11204.
37. Roller, P. P., Wu, L., Zhang, Z.-Y., and Burke, T. R. (1998) Bioorg. Med. Chem. Lett. 8, 2149-2150.
38. Barford, D., Flint, A. J., and Tonks, N. K. (1994) Science 263, 1397-1404.
39. Bilwes, A. M. den Hertog, J., Hunter, T., and Noel, J. P. (1996) Nature 382, 555-559.
40. Yuvaniyama, J., Denu, J. M., Dixon, J. E., and Saper, M. A. (1996) Science 272, 1328-1331.
41. Fauman, E. B., Cogswell, J. P., Lovejoy, B., Rocque, W. J., Holmes, W., Montana, V. G., Piwnica-Worms, H., Rink, M. J., and Saper, M. A. (1998) Cell 93, 617-625.