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Biochemistry

Volumn 41, Issue 25, 2002, Pages 7989-7997

A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents

(2) O'Reilly, Erin K a Kreuzer, Kenneth N a

a DUKE UNIVERSITY MEDICAL CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG HYPERSENSITIVITY;

AMINO ACIDS; DNA; ENZYMES; MUTAGENESIS;

BACTERIOPHAGES;

ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); ELLIPTICINE; MITOXANTRONE; OXOLINIC ACID;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE; COVALENT BOND; DNA CLEAVAGE; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME INHIBITION; ENZYME SUBUNIT; HYPERSENSITIVITY; MUTANT; PRIORITY JOURNAL; PROTEIN DNA INTERACTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMSACRINE; ANTINEOPLASTIC AGENTS; BACTERIOPHAGE T4; BINDING SITES; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; DNA, SUPERHELICAL; ELLIPTICINES; ENZYME INHIBITORS; FILTRATION; GLYCINE; MITOXANTRONE; MOLECULAR SEQUENCE DATA; OXOLINIC ACID; PODOPHYLLOTOXIN; POINT MUTATION; VALINE;

UNIDENTIFIED BACTERIOPHAGE;

EID: 0037172804 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi025897m Document Type: Article

Times cited : (30)

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