Mutations of the bacteriophage T4 type II DNA topoisomerase that alter sensitivity to antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide and an antibacterial quinolone

Cancer Research

Volumn 58, Issue 6, 1998, Pages 1260-1267

  Freudenreich, Catherine H ^a,d   Chang, Christine ^b,d   Kreuzer, Kenneth N ^c,d  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMSACRINE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; OXOLINIC ACID; PROTEIN SUBUNIT; QUINOLONE;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE; CANCER RESISTANCE; ENZYME ACTIVE SITE; GENE MUTATION; HYPERSENSITIVITY; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMSACRINE; ANTINEOPLASTIC AGENTS; BACTERIOPHAGE T4; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE, MICROBIAL; ENZYME INHIBITORS; OXOLINIC ACID; POINT MUTATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032521447     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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