SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 2, 2002, Pages 137-140

N-Acyl-l-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation

(9) Chen, Li a Tilley, Jefferson a Trilles, Richard V a Yun, Weiya a Fry, David a Cook, Charles a Rowan, Karen a Schwinge, Virginia a Campbell, Robert a

a HOFFMANN LA ROCHE INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CYCLOPEPTIDE; PHENYLALANINE DERIVATIVE; RECEPTOR BLOCKING AGENT; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG POTENCY; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

CELL LINE; INTEGRIN ALPHA4BETA1; INTEGRINS; MODELS, MOLECULAR; MOLECULAR MIMICRY; PEPTIDES, CYCLIC; PHENYLALANINE; RECEPTORS, LYMPHOCYTE HOMING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037147764 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00711-9 Document Type: Article

Times cited : (25)

References (13)

1
- 0000131446
- Mousa, S. A., Ed.; Springer
- (1998) Cell Adhesion Molecules and Matrix Proteins: Role in Health and Diseases , pp. 133
- Elices, M.¹

2
- 0033545639
- (1999) J. Med. Chem. , vol.42 , pp. 920
- Lin, K.-C.¹ Ateeq, H.S.² Hsiung, S.H.³ Chong, L.T.⁴ Zimmerman, C.N.⁵ Castro, A.⁶ Lee, W.-C.⁷ Hammond, C.E.⁸ Kalkunte, S.⁹ Chen, L.-L.¹⁰ Pepinsky, R.B.¹¹ Leone, D.R.¹² Sprague, A.G.¹³ Abraham, W.M.¹⁴ Gill, A.¹⁵ Lobb, R.A.¹⁶ Adams, S.P.¹⁷

3
- 0032135083
- (1998) Curr. Opin. Chem. Biol. , vol.2 , pp. 453
- Lin, K.-C.¹ Castro, A.C.²

4
- 0001769481
- (1999) Curr. Opin. Antiinflammat. Immunomodulat. Investigat. Drugs , vol.1 , pp. 14
- Elices, M.¹

5
- 9844223916
- (1997) J. Med. Chem. , vol.40 , pp. 3359
- Jackson, D.¹ Quan, C.² Artis, D.R.³ Rawson, T.⁴ Blackburn, B.⁵ Struble, M.⁶ Fitzgerald, G.⁷ Chan, K.⁸ Mullins, S.⁹ Burnier, J.P.¹⁰ Fairbrother, W.J.¹¹ Clark, K.¹² Berisini, M.¹³ Chui, H.¹⁴ Renz, M.¹⁵ Jones, S.¹⁶ Fong, S.¹⁷

6
- 0034608629
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 1171
- Fotouhi, N.¹ Joshi, P.² Fry, D.³ Cook, C.⁴ Tilley, J.W.⁵ Kaplan, G.⁶ Hanglow, A.⁷ Rowan, K.⁸ Schwinge, V.⁹ Wolitzy, B.¹⁰

7
- 0034678645
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 725
- Chen, L.¹ Tilley, J.W.² Huang, T.-N.³ Miklowski, D.⁴ Trilles, R.V.⁵ Guthrie, R.W.⁶ Luk, K.⁷ Hanglow, A.⁸ Rowan, K.⁹ Schwinge, V.¹⁰ Wolitzky, B.¹¹

8
- 0034678785
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 729
- Chen, L.¹ Tilley, J.W.² Guthrie, R.W.³ Mennona, F.⁴ Huang, T.-N.⁵ Kaplan, G.⁶ Trilles, R.⁷ Miklowski, D.⁸ Huby, N.⁹ Schwinge, V.¹⁰ Wolitzky, B.¹¹ Rowan, K.¹²

9
- 0035825366
- (2001) Bioorg. Med. Chem. Lett. , vol.11 , pp. 1
- Tilley, J.¹ Kaplan, K.² Rowan, K.³ Schwinge, V.⁴ Wolitzky, B.⁵

10
- 2042524607
- note

11
- 0000740766
- (1993) J. Am. Chem. Soc. , vol.115 , pp. 10125
- Burk, M.J.¹ Feaster, J.E.² Nugent, W.A.³ Harlow, R.L.⁴

12
- 2042493172
- note

13
- 0000296529
- WO 9910312, 1999; WO 9910313, 1999
- (1999) Chem. Abstr. , vol.130 , pp. 196
- Chen, L.¹ Guthrie, R.W.² Huang, T.-N.³ Hull, K.G.⁴ Sidduri, A.⁵ Tilley, J.W.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.