Displacement of Mn2+ from RNA by K+, Mg2+, neomycin B, and an arginine-rich peptide: Indirect detection of nucleic acid/ligand interactions using phosphorus relaxation enhancement

Journal of the American Chemical Society

Volumn 124, Issue 50, 2002, Pages 14934-14939

  Summers, Jack S ^a   Shimko, John ^a   Freedman, Fredric L ^a   Badger, Christopher T ^a,b   Sturgess, Michael ^a  

^a Message Pharmaceuticals Inc   (United States)

^b UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION CONSTANT; HAIRPIN-FORMING SEQUENCES;

DRUG PRODUCTS; FLUORESCENCE; NUCLEAR MAGNETIC RESONANCE; RNA; SATURATION (MATERIALS COMPOSITION);

CHEMICAL ANALYSIS;

ARGININE; FRAMYCETIN; LIGAND; MAGNESIUM ION; MANGANESE; OLIGONUCLEOTIDE; PEPTIDE; PHOSPHORUS DERIVATIVE; POTASSIUM ION; REV PROTEIN; RNA; URIDINE DERIVATIVE; CATION; MAGNESIUM; METAL; POTASSIUM;

ARTICLE; CHEMICAL STRUCTURE; EQUILIBRIUM CONSTANT; FLUORESCENCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID ANALYSIS; POLARIZATION; AMINO ACID SEQUENCE; CHEMISTRY; CONFORMATION; FLUORESCENCE POLARIZATION; KINETICS; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE;

AMINO ACID SEQUENCE; ARGININE; BASE SEQUENCE; CATIONS; FLUORESCENCE POLARIZATION; FRAMYCETIN; KINETICS; MAGNESIUM; MANGANESE; METALS; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; PEPTIDES; POTASSIUM; RNA;

EID: 0037132430     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja027829t     Document Type: Article

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