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Volumn 62, Issue 24, 2002, Pages 7234-7240

Both E7 and CpG-oligodeoxynucleotide are required for protective immunity against challenge with human papillomavirus 16 (E6/E7) immortalized tumor cells: Involvement of CD4+ and CD8+ T cells in protection

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; OLIGODEOXYNUCLEOTIDE; PROTEIN; PROTEIN E7; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 0037115506     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (82)

References (45)
  • 1
    • 0345120862 scopus 로고    scopus 로고
    • Oligodeoxynucleotides containing CpG motifs induce IL-12. IL-18 and IFN-γ production in cells from allergic individuals and inhibit IgE synthesis in vitro
    • Bohle, B., Jahn-Schmid, B., Maurer, D., Kraft, D., and Ebner, C. Oligodeoxynucleotides containing CpG motifs induce IL-12. IL-18 and IFN-γ production in cells from allergic individuals and inhibit IgE synthesis in vitro. Eur. J. Immunol., 29: 2344-2353, 1999.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2344-2353
    • Bohle, B.1    Jahn-Schmid, B.2    Maurer, D.3    Kraft, D.4    Ebner, C.5
  • 2
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon γ
    • Klinman, D. M., Yi, A. K., Beaucage, S. L., Conover, J., and Krieg, A. M. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon γ. Proc. Natl. Acad. Sci. USA, 93: 2879-2883, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2879-2883
    • Klinman, D.M.1    Yi, A.K.2    Beaucage, S.L.3    Conover, J.4    Krieg, A.M.5
  • 4
    • 0030239828 scopus 로고    scopus 로고
    • Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
    • Ballas, Z. K., Rasmussen, W. L., and Krieg, A. M. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J. Immunol., 157: 1840-1845, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 1840-1845
    • Ballas, Z.K.1    Rasmussen, W.L.2    Krieg, A.M.3
  • 5
    • 0034532681 scopus 로고    scopus 로고
    • Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins
    • Sparwasser, T., Vabulas, R. M., Villmow, B., Lipford, G. B., and Wagner, H. Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins. Eur. J. Immunol., 30: 3591-3597, 2000.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3591-3597
    • Sparwasser, T.1    Vabulas, R.M.2    Villmow, B.3    Lipford, G.B.4    Wagner, H.5
  • 6
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser, T., Koch, E. S., Vabulas, R. M., Heeg, K., Lipford, G. B., Ellwart, J. W., and Wagner, H. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol., 28: 2045-2054, 1998.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2045-2054
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3    Heeg, K.4    Lipford, G.B.5    Ellwart, J.W.6    Wagner, H.7
  • 7
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligonucleotides act as adjuvants that switch on T helper 1 (Th1) immunity
    • Chu, R. S., Targoni, O. S., Krieg, A. M., Lehmann, P. V., and Harding, C. V. CpG oligonucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J. Exp. Med., 186: 1623-1631, 1997.
    • (1997) J. Exp. Med. , vol.186 , pp. 1623-1631
    • Chu, R.S.1    Targoni, O.S.2    Krieg, A.M.3    Lehmann, P.V.4    Harding, C.V.5
  • 8
    • 0031215046 scopus 로고    scopus 로고
    • The preferential induction of Th1 immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA
    • Leclerc, C., Deriaud, E., Rojas, M., and Whalen, R. G. The preferential induction of Th1 immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA. Cell. Immunol., 179: 97-106, 1997.
    • (1997) Cell. Immunol. , vol.179 , pp. 97-106
    • Leclerc, C.1    Deriaud, E.2    Rojas, M.3    Whalen, R.G.4
  • 9
    • 0031569601 scopus 로고    scopus 로고
    • Contribution of CpG motifs to the immunogenicity of DNA vaccines
    • Klinman, D. M., Yamshchikov, G., and Ishigatsubo, Y. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol., 158: 3635-3639, 1997.
    • (1997) J. Immunol. , vol.158 , pp. 3635-3639
    • Klinman, D.M.1    Yamshchikov, G.2    Ishigatsubo, Y.3
  • 10
    • 0032531036 scopus 로고    scopus 로고
    • Activation of cutaneous dendritic cells by CpG-containing oligonucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA
    • Jakob, T., Walker, P. S., Krieg, A. M., Udey, M. C., and Vogel, J. C. Activation of cutaneous dendritic cells by CpG-containing oligonucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J. Immunol., 161: 3042-3049, 1998.
    • (1998) J. Immunol. , vol.161 , pp. 3042-3049
    • Jakob, T.1    Walker, P.S.2    Krieg, A.M.3    Udey, M.C.4    Vogel, J.C.5
  • 12
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis, H. L., Weeranta, R., Waldschmidt, T. J., Tygrett, L., Schorr, J., and Krieg, A. M. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J. Immunol., 160: 870-876, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 870-876
    • Davis, H.L.1    Weeranta, R.2    Waldschmidt, T.J.3    Tygrett, L.4    Schorr, J.5    Krieg, A.M.6
  • 13
    • 0034547841 scopus 로고    scopus 로고
    • APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells
    • Warren, T. L., Bhatia, S. K., Acosta, A. M., Dahle, C. E., Ratliff, T. L., Krieg, A. M., and Weiner, G. J. APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells. J. Immunol., 165: 6244-6251, 2000.
    • (2000) J. Immunol. , vol.165 , pp. 6244-6251
    • Warren, T.L.1    Bhatia, S.K.2    Acosta, A.M.3    Dahle, C.E.4    Ratliff, T.L.5    Krieg, A.M.6    Weiner, G.J.7
  • 14
    • 0030955249 scopus 로고    scopus 로고
    • Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization
    • Weiner, G. J., Liu, H-M., Wooldridge, J. E., Dahle, C. E., and Krieg, A. M. Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization. Proc. Natl. Acad. Sci. USA, 94: 10833-10837, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10833-10837
    • Weiner, G.J.1    Liu, H.-M.2    Wooldridge, J.E.3    Dahle, C.E.4    Krieg, A.M.5
  • 15
    • 0029982850 scopus 로고    scopus 로고
    • DNA vaccine for hepatitis B: Evidence for immunogenicity in chimpanzees and comparison with other vaccines
    • Davis, H. L., McCluskie, M. J., Gerin, J. L., and Purcell, R. H. DNA vaccine for hepatitis B: Evidence for immunogenicity in chimpanzees and comparison with other vaccines. Proc. Natl. Acad. Sci. USA, 93: 7213-7218, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7213-7218
    • Davis, H.L.1    McCluskie, M.J.2    Gerin, J.L.3    Purcell, R.H.4
  • 17
    • 0035284751 scopus 로고    scopus 로고
    • Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract
    • Scott Gallichan, W., Woolstencroft, R. N., Guarasci, T., McCluskie, M. J., Davis, H. L., and Rosenthal, K. L. Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract. J. Immunol., 166: 3451-3457, 2001.
    • (2001) J. Immunol. , vol.166 , pp. 3451-3457
    • Scott Gallichan, W.1    Woolstencroft, R.N.2    Guarasci, T.3    McCluskie, M.J.4    Davis, H.L.5    Rosenthal, K.L.6
  • 18
    • 0025886714 scopus 로고
    • Human papillomaviruses in the pathogenesis of anogenital cancer
    • zur Hausen, H. Human papillomaviruses in the pathogenesis of anogenital cancer. Virol., 184: 9-13, 1991.
    • (1991) Virol. , vol.184 , pp. 9-13
    • Zur Hausen, H.1
  • 19
    • 0025953696 scopus 로고
    • The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
    • Scheffner, M., Munger, K., Bryne, J. C., and Howley, P. M. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl. Acad. Sci. USA, 88: 5523-5527, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5523-5527
    • Scheffner, M.1    Munger, K.2    Bryne, J.C.3    Howley, P.M.4
  • 20
    • 0025271203 scopus 로고
    • Association of HPV type 16 and 18 E6 protein with p53
    • Werness, B. A., Levine, A. J., and Howley, P. M. Association of HPV type 16 and 18 E6 protein with p53. Science (Wash. DC), 248: 76-79, 1990.
    • (1990) Science (Wash. DC) , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 21
    • 0024535228 scopus 로고
    • The human papilomavirus-16 E7 oncoprotein is able to bind the retinoblastoma gene product
    • Dyson, N., Howley, P. M., Munger, K., and Harlow, E. The human papilomavirus-16 E7 oncoprotein is able to bind the retinoblastoma gene product. Science (Wash. DC), 243: 934-937, 1989.
    • (1989) Science (Wash. DC) , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 22
    • 0029793131 scopus 로고    scopus 로고
    • T cell proliferative responses against human papillomavirus type 16 E7 oncoprotein are most prominent in cervical intraepithelial neoplasia patients with a persistent viral infection
    • de Gruijl, T. D., Bontkes, H. J., Stukart, M. J., Walboomers, J. M., Remmink, A. J., Verheijen, R. H., Helmerhorst, T. J., Meijer, C. J., and Scheper, R. J. T cell proliferative responses against human papillomavirus type 16 E7 oncoprotein are most prominent in cervical intraepithelial neoplasia patients with a persistent viral infection. J. Gen. Virol., 77: 2183-2191, 1996.
    • (1996) J. Gen. Virol. , vol.77 , pp. 2183-2191
    • De Gruijl, T.D.1    Bontkes, H.J.2    Stukart, M.J.3    Walboomers, J.M.4    Remmink, A.J.5    Verheijen, R.H.6    Helmerhorst, T.J.7    Meijer, C.J.8    Scheper, R.J.9
  • 23
    • 0032995535 scopus 로고    scopus 로고
    • Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16
    • Fernando, G. J. P., Murray, B., Zhou, J., and Frazer, I. H. Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16. Clin. Exp. Immunol., 115: 397-403, 1999.
    • (1999) Clin. Exp. Immunol. , vol.115 , pp. 397-403
    • Fernando, G.J.P.1    Murray, B.2    Zhou, J.3    Frazer, I.H.4
  • 24
    • 0035328523 scopus 로고    scopus 로고
    • Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen
    • Hung, C. F., Cheng, W. F., Hsu, K. F., Chai, C. Y., He, L., Ling, M., and Wu, T. C. Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen. Cancer Res., 61: 3698-3703, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3698-3703
    • Hung, C.F.1    Cheng, W.F.2    Hsu, K.F.3    Chai, C.Y.4    He, L.5    Ling, M.6    Wu, T.C.7
  • 25
    • 0034802089 scopus 로고    scopus 로고
    • Regression of established human papillomavirus type 16 (HPV-16) immortalized tumors in vivo by vaccinia viruses expressing different forms of HPV-16 E7 correlates with enhanced CD8(+) T-cell responses that home to the tumor site
    • Lamikanra, A., Pan, Z. K., Isaacs, S. N., Wu, T. C., and Paterson, Y. Regression of established human papillomavirus type 16 (HPV-16) immortalized tumors in vivo by vaccinia viruses expressing different forms of HPV-16 E7 correlates with enhanced CD8(+) T-cell responses that home to the tumor site. J. Virol., 75: 9654-9664, 2001.
    • (2001) J. Virol. , vol.75 , pp. 9654-9664
    • Lamikanra, A.1    Pan, Z.K.2    Isaacs, S.N.3    Wu, T.C.4    Paterson, Y.5
  • 27
    • 0033994625 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer
    • Liu, D. W., Tsao, Y. P., Kung, J. T., Ding, Y. A., Sytwu, H. K., Xiao, X., and Chen, S. L. Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer. J. Virol., 74: 2888-2894, 2000.
    • (2000) J. Virol. , vol.74 , pp. 2888-2894
    • Liu, D.W.1    Tsao, Y.P.2    Kung, J.T.3    Ding, Y.A.4    Sytwu, H.K.5    Xiao, X.6    Chen, S.L.7
  • 28
    • 0030009053 scopus 로고    scopus 로고
    • Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen
    • Londono, L. P., Chatfield, S., Tindle, R. W., Herd, K., Gao, X. M., Frazer, I., and Dougan, G. Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen. Vaccine, 14: 545-552, 1996.
    • (1996) Vaccine , vol.14 , pp. 545-552
    • Londono, L.P.1    Chatfield, S.2    Tindle, R.W.3    Herd, K.4    Gao, X.M.5    Frazer, I.6    Dougan, G.7
  • 29
    • 0027320440 scopus 로고
    • Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells
    • Feltkamp, M. C., Smits, H. L., Vierboom, M. P., Minnaar, R. P., de Jongh, B. M., Drijfhout, J. W., ter Schegget, J., Melief, C. J., and Kast, W. M. Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells. Eur. J. Immunol., 23: 2242-2249, 1993.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3    Minnaar, R.P.4    De Jongh, B.M.5    Drijfhout, J.W.6    Ter Schegget, J.7    Melief, C.J.8    Kast, W.M.9
  • 30
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72: 248-254, 1976.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 31
    • 0030735550 scopus 로고    scopus 로고
    • Protective immunity against heterologous challenge with encephalomyocarditis virus by VP1 DNA vaccination: Effect of co-injection with a granulocyte, macrophage-colony stimulating factor gene
    • Sin, J. I., Sung, J. H., Suh, Y. S., Lee, A. H., Chung, J. H., and Sung, Y. C. Protective immunity against heterologous challenge with encephalomyocarditis virus by VP1 DNA vaccination: Effect of co-injection with a granulocyte, macrophage-colony stimulating factor gene. Vaccine, 15: 1827-1833, 1997.
    • (1997) Vaccine , vol.15 , pp. 1827-1833
    • Sin, J.I.1    Sung, J.H.2    Suh, Y.S.3    Lee, A.H.4    Chung, J.H.5    Sung, Y.C.6
  • 32
    • 0034467315 scopus 로고    scopus 로고
    • DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th-1 type CD4+ T cell-mediated protecetive immunity against herpes simplex virus-2 in vivo
    • Sin, J. I., Kim, J., Pachuk, C., Satishchanran, C., and Weiner, D. B. DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th-1 type CD4+ T cell-mediated protecetive immunity against herpes simplex virus-2 in vivo. J. Virol., 74: 11173-11180, 2000.
    • (2000) J. Virol. , vol.74 , pp. 11173-11180
    • Sin, J.I.1    Kim, J.2    Pachuk, C.3    Satishchanran, C.4    Weiner, D.B.5
  • 33
    • 0034921349 scopus 로고    scopus 로고
    • Modulation of cellular responses by plasmid CD40L: CD40L plasmid vectors enhance antigen-specific helper T cell type 1 CD4+ T cell-mediated protective immunity against herpes simplex virus type 2 in vivo
    • Sin, J. I., Kim, J. J., Zhang, D. H., and Weiner, D. B. Modulation of cellular responses by plasmid CD40L: CD40L plasmid vectors enhance antigen-specific helper T cell type 1 CD4+ T cell-mediated protective immunity against herpes simplex virus type 2 in vivo. Hum. Gene Ther., 12: 1091-1102, 2001.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1091-1102
    • Sin, J.I.1    Kim, J.J.2    Zhang, D.H.3    Weiner, D.B.4
  • 35
    • 0030068375 scopus 로고    scopus 로고
    • Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen
    • Lin, K. Y., Guarnieri, F. G., Staveley-O'Carroll, K. F., Levitsky, H. I., August. J. T., Pardoll, D. M., and Wu, T. C. Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen. Cancer Res., 56: 21-26, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 21-26
    • Lin, K.Y.1    Guarnieri, F.G.2    Staveley-O'Carroll, K.F.3    Levitsky, H.I.4    August, J.T.5    Pardoll, D.M.6    Wu, T.C.7
  • 36
    • 0027184837 scopus 로고
    • The anomalous electrephoretic behavior of the human papillomavirus type 16 E7 protein is due to the high content of the acidic amino acid residues
    • Armstrong, D. J., and Roman, A. The anomalous electrephoretic behavior of the human papillomavirus type 16 E7 protein is due to the high content of the acidic amino acid residues. Biochem. Biophys. Res. Commun., 192: 1380-1387, 1993.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 1380-1387
    • Armstrong, D.J.1    Roman, A.2
  • 39
    • 0032533269 scopus 로고    scopus 로고
    • Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor
    • Liu, H-M., Newbrough, S. E., Bhatia, S. K., Dahle, C. E., Krieg, A. M., and Weiner, G. J. Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor. Blood, 92: 3730-3736, 1998.
    • (1998) Blood , vol.92 , pp. 3730-3736
    • Liu, H.-M.1    Newbrough, S.E.2    Bhatia, S.K.3    Dahle, C.E.4    Krieg, A.M.5    Weiner, G.J.6
  • 40
    • 0032168355 scopus 로고    scopus 로고
    • CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenges
    • Krieg, A. M., Love-Homan, L., Yi, A. K., and Harty, J. T. CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenges. J. Immunol., 161: 2428-2434, 1998.
    • (1998) J. Immunol. , vol.161 , pp. 2428-2434
    • Krieg, A.M.1    Love-Homan, L.2    Yi, A.K.3    Harty, J.T.4
  • 41
    • 0034927083 scopus 로고    scopus 로고
    • Protection of BALB/c mice against Brucella abortus 544 challenge by vaccination with bacterioferritin or P39 recombinant proteins with CpG oligodeoxynucleotides as adjuvant
    • Al-Mariri, A., Tibor, A., Mertens, P., De Bolle. X., Michel, P., Godefroid, J., Walravens, K., and Letesson, J. J. Protection of BALB/c mice against Brucella abortus 544 challenge by vaccination with bacterioferritin or P39 recombinant proteins with CpG oligodeoxynucleotides as adjuvant. Infect. Immun., 69: 4816-4822, 2001.
    • (2001) Infect. Immun. , vol.69 , pp. 4816-4822
    • Al-Mariri, A.1    Tibor, A.2    Mertens, P.3    De Bolle, X.4    Michel, P.5    Godefroid, J.6    Walravens, K.7    Letesson, J.J.8
  • 42
    • 0025739093 scopus 로고
    • Antiviral actions of interferon: Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • Samuel, C. E. Antiviral actions of interferon: Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology, 183: 1-11, 1991.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 43
    • 0028100452 scopus 로고
    • Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon Interferon-γ (IFN-γ)
    • Smith. P. M., Wolcott. R. M., Chervenak, R., and Jennings, S. R. Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-γ (IFN-γ). Virology, 202: 76-88, 1994.
    • (1994) Virology , vol.202 , pp. 76-88
    • Smith, P.M.1    Wolcott, R.M.2    Chervenak, R.3    Jennings, S.R.4
  • 45
    • 0026728649 scopus 로고
    • Proteasomes are regulated by interferon γ: Implications for antigen processing
    • Yang, Y., Waters, J. B., Fruh, K., and Peterson, P. A. Proteasomes are regulated by interferon γ: Implications for antigen processing. Proc. Natl. Acad. Sci. USA, 89: 4928-4932, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4928-4932
    • Yang, Y.1    Waters, J.B.2    Fruh, K.3    Peterson, P.A.4


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