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Volumn 58, Issue 5, 2002, Pages 447-454

Alternative splicing of the GABAA receptor α4 subunit creates a severely truncated mRNA

Author keywords

Aminobutyric acid; Dominant negative; Folding; Glycosylation; Post translational regulation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AMINO ACID; MESSENGER RNA; RECEPTOR SUBUNIT; SIGNAL PEPTIDE;

EID: 0037107043     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(02)00816-X     Document Type: Article
Times cited : (10)

References (46)
  • 2
    • 0030852616 scopus 로고    scopus 로고
    • A receptors containing the α4-subunit: Prevalence, distribution, pharmacology, and subunit architecture in situ
    • A receptors containing the α4-subunit: Prevalence, distribution, pharmacology, and subunit architecture in situ. J. Neurochem. 69:1997;806-814.
    • (1997) J. Neurochem. , vol.69 , pp. 806-814
    • Benke, D.1    Michel, C.2    Mohler, H.3
  • 3
    • 0028138844 scopus 로고
    • Site-directed mutagenesis of N-linked glycosylation sites on the γ-aminobutyric acid type A receptor α1 subunit
    • Buller A.L., Hastings G.A., Kirkness E.F., Fraser C.M. Site-directed mutagenesis of N-linked glycosylation sites on the γ-aminobutyric acid type A receptor α1 subunit. Mol. Pharmacol. 46:1994;858-865.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 858-865
    • Buller, A.L.1    Hastings, G.A.2    Kirkness, E.F.3    Fraser, C.M.4
  • 5
    • 0036142862 scopus 로고    scopus 로고
    • Killing the messenger: New insights into nonsense-mediated mRNA decay
    • Byers P.H. Killing the messenger: New insights into nonsense-mediated mRNA decay. J. Clin. Invest. 109:2002;3-6.
    • (2002) J. Clin. Invest. , vol.109 , pp. 3-6
    • Byers, P.H.1
  • 7
    • 0035282615 scopus 로고    scopus 로고
    • Generating diversity at GABAergic synapses
    • Cherubini E., Conti F. Generating diversity at GABAergic synapses. Trends Neurosci. 24:2001;155-162.
    • (2001) Trends Neurosci. , vol.24 , pp. 155-162
    • Cherubini, E.1    Conti, F.2
  • 8
    • 0032568901 scopus 로고    scopus 로고
    • A receptor α4 subunit to electroshock seizures
    • A receptor α4 subunit to electroshock seizures. Neurosci. Lett. 250:1998;17-20.
    • (1998) Neurosci. Lett. , vol.250 , pp. 17-20
    • Clark, M.1
  • 9
    • 0030043594 scopus 로고    scopus 로고
    • Assembly and cell surface expression of heteromeric and homomeric γ-aminobutyric acid type A receptors
    • Connolly C.N., Krishek B.J., McDonald B.J., Smart T.G., Moss S.J. Assembly and cell surface expression of heteromeric and homomeric γ-aminobutyric acid type A receptors. J. Biol. Chem. 271:1996;89-96.
    • (1996) J. Biol. Chem. , vol.271 , pp. 89-96
    • Connolly, C.N.1    Krishek, B.J.2    McDonald, B.J.3    Smart, T.G.4    Moss, S.J.5
  • 11
    • 0029040991 scopus 로고
    • Role of the endoplasmic reticulum chaperone calnexin in subunit folding and assembly of nicotinic acetylcholine receptors
    • Gelman M.S., Chang W., Thomas D.Y., Bergeron J.J.M., Prives J.V. Role of the endoplasmic reticulum chaperone calnexin in subunit folding and assembly of nicotinic acetylcholine receptors. J. Biol. Chem. 270:1995;15085-15092.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15085-15092
    • Gelman, M.S.1    Chang, W.2    Thomas, D.Y.3    Bergeron, J.J.M.4    Prives, J.V.5
  • 13
    • 0029416984 scopus 로고
    • A receptor gating kinetics on the α-subunit isoform: Implications for structure-function relations and synaptic transmission
    • A receptor gating kinetics on the α-subunit isoform: Implications for structure-function relations and synaptic transmission. J. Physiol. (Lond.). 489:1995;529-543.
    • (1995) J. Physiol. (Lond.) , vol.489 , pp. 529-543
    • Gingrich, K.J.1    Roberts, W.A.2    Kass, R.S.3
  • 16
    • 0031446639 scopus 로고    scopus 로고
    • Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor
    • Grosse R., Schoneberg T., Schultz G., Guderman T. Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor. Mol. Endocrinol. 11:1997;1305-1318.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 1305-1318
    • Grosse, R.1    Schoneberg, T.2    Schultz, G.3    Guderman, T.4
  • 17
    • 0030827972 scopus 로고    scopus 로고
    • Suppression of slow delayed rectifier current by a truncated isoform of KvLQT1 cloned from normal human heart
    • Jiang M., Tseng-Crank J., Tseng G.N. Suppression of slow delayed rectifier current by a truncated isoform of KvLQT1 cloned from normal human heart. J. Biol. Chem. 272:1997;24109-24112.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24109-24112
    • Jiang, M.1    Tseng-Crank, J.2    Tseng, G.N.3
  • 18
    • 0029848478 scopus 로고    scopus 로고
    • Characterization of a cerebellar granule cell-specific gene encoding the γ-aminobutyric acid type A receptor α6 subunit
    • Jones A., Bahn S., Grant A.L., Köhler M., Wisden W. Characterization of a cerebellar granule cell-specific gene encoding the γ-aminobutyric acid type A receptor α6 subunit. J. Neurochem. 67:1996;907-916.
    • (1996) J. Neurochem. , vol.67 , pp. 907-916
    • Jones, A.1    Bahn, S.2    Grant, A.L.3    Köhler, M.4    Wisden, W.5
  • 20
    • 0031877405 scopus 로고    scopus 로고
    • Alternative splicing of follicle-stimulating hormone receptor pre-mRNA: Cloning and characterization of two alternatively spliced mRNA transcripts
    • Kraaij R., Verhoef-Post M., Grootegoed J.A., Themmen A.P. Alternative splicing of follicle-stimulating hormone receptor pre-mRNA: Cloning and characterization of two alternatively spliced mRNA transcripts. J. Endocrinol. 158:1998;127-136.
    • (1998) J. Endocrinol. , vol.158 , pp. 127-136
    • Kraaij, R.1    Verhoef-Post, M.2    Grootegoed, J.A.3    Themmen, A.P.4
  • 21
    • 0026615268 scopus 로고
    • A receptor subunit messenger RNAs in the rat brain. III. Embryonic and postnatal development
    • A receptor subunit messenger RNAs in the rat brain. III. Embryonic and postnatal development. J. Neurosci. 12:1992;4151-4172.
    • (1992) J. Neurosci. , vol.12 , pp. 4151-4172
    • Laurie, D.J.1    Wisden, W.2    Seeburg, P.H.3
  • 22
    • 0345345498 scopus 로고    scopus 로고
    • A receptor subunit mRNAs in rats and mice
    • A receptor subunit mRNAs in rats and mice. J. Neurosci. Methods. 85:1998;89-98.
    • (1998) J. Neurosci. Methods , vol.85 , pp. 89-98
    • Liu, Z.F.1    Burt, D.R.2
  • 23
    • 0031793761 scopus 로고    scopus 로고
    • Characterization of a soluble KGF receptor cDNA from human corneal and breast epithelial cells
    • Liu J.J., Shay J.W., Wilson S.E. Characterization of a soluble KGF receptor cDNA from human corneal and breast epithelial cells. Invest. Ophthalmol. Vis. Sci. 39:1998;2584-2593.
    • (1998) Invest. Ophthalmol. Vis. Sci. , vol.39 , pp. 2584-2593
    • Liu, J.J.1    Shay, J.W.2    Wilson, S.E.3
  • 26
    • 0032584229 scopus 로고    scopus 로고
    • Cloning and functional expression of alternative spliced variants of the ρ1 γ-aminobutyrate receptor
    • Martinez-Torres A., Vazquez A.E., Panicker M.M., Miledi R. Cloning and functional expression of alternative spliced variants of the ρ1 γ-aminobutyrate receptor. Proc. Natl. Acad. Sci. U.S.A. 95:1998;4019-4022.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 4019-4022
    • Martinez-Torres, A.1    Vazquez, A.E.2    Panicker, M.M.3    Miledi, R.4
  • 29
    • 0029124881 scopus 로고
    • Identification of a gephyrin binding motif on the glycine receptor β subunit
    • Meyer G., Kirsch J., Betz H., Langosch D. Identification of a gephyrin binding motif on the glycine receptor β subunit. Neuron. 15:1995;563-572.
    • (1995) Neuron , vol.15 , pp. 563-572
    • Meyer, G.1    Kirsch, J.2    Betz, H.3    Langosch, D.4
  • 30
    • 0035319805 scopus 로고    scopus 로고
    • Constructing inhibitory synapses
    • Moss S.J., Smart T.G. Constructing inhibitory synapses. Nat. Rev. Neurosci. 2:2001;240-250.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 240-250
    • Moss, S.J.1    Smart, T.G.2
  • 31
    • 0029827245 scopus 로고    scopus 로고
    • Expression and function of TrkB variants in developing sensory neurons
    • Ninkina N., Adu J., Fischer A., Pinon L.G., Buchman V.L., Davies A.M. Expression and function of TrkB variants in developing sensory neurons. EMBO J. 15:1996;6385-6393.
    • (1996) EMBO J. , vol.15 , pp. 6385-6393
    • Ninkina, N.1    Adu, J.2    Fischer, A.3    Pinon, L.G.4    Buchman, V.L.5    Davies, A.M.6
  • 32
    • 0033579988 scopus 로고    scopus 로고
    • An isoform of Nurr1 functions as a negative inhibitor of the NGFI-B family signaling
    • Ohkura N., Hosono T., Maruyama K., Tsukada T., Yamaguchi K. An isoform of Nurr1 functions as a negative inhibitor of the NGFI-B family signaling. Biochim. Biophys. Acta. 1444:1999;69-79.
    • (1999) Biochim. Biophys. Acta , vol.1444 , pp. 69-79
    • Ohkura, N.1    Hosono, T.2    Maruyama, K.3    Tsukada, T.4    Yamaguchi, K.5
  • 33
    • 0033535545 scopus 로고    scopus 로고
    • Synaptogenesis: The MAP location of GABA receptors
    • Passafaro M., Sheng M. Synaptogenesis: The MAP location of GABA receptors. Curr. Biol. 9:1999;R261-R263.
    • (1999) Curr. Biol. , vol.9
    • Passafaro, M.1    Sheng, M.2
  • 39
    • 0026595697 scopus 로고
    • The N-terminal domains of acetylcholine receptor subunits contain recognition signals for the initial steps of receptor assembly
    • Verrall S., Hall Z.W. The N-terminal domains of acetylcholine receptor subunits contain recognition signals for the initial steps of receptor assembly. Cell. 68:1992;23-31.
    • (1992) Cell , vol.68 , pp. 23-31
    • Verrall, S.1    Hall, Z.W.2
  • 43
    • 0033520987 scopus 로고    scopus 로고
    • Posttranslational quality control: Folding, refolding, and degrading proteins
    • Wickner S., Maurizi M.R., Gottesman S. Posttranslational quality control: Folding, refolding, and degrading proteins. Science. 286:1999;1888-1893.
    • (1999) Science , vol.286 , pp. 1888-1893
    • Wickner, S.1    Maurizi, M.R.2    Gottesman, S.3
  • 45
    • 0034646780 scopus 로고    scopus 로고
    • An alternatively spliced transcript of the rat nociceptin receptor ORL1 gene encodes a truncated receptor
    • Xie G., Ito E., Maruyama K., Pietruck C., Sharma M., Yu L., Pierce Palmer P. An alternatively spliced transcript of the rat nociceptin receptor ORL1 gene encodes a truncated receptor. Mol. Brain Res. 77:2000;1-9.
    • (2000) Mol. Brain Res. , vol.77 , pp. 1-9
    • Xie, G.1    Ito, E.2    Maruyama, K.3    Pietruck, C.4    Sharma, M.5    Yu, L.6    Pierce Palmer, P.7
  • 46
    • 0028972886 scopus 로고
    • A receptor α4 subunit: Identification of a unique diazepam-insensitive binding site
    • A receptor α4 subunit: Identification of a unique diazepam-insensitive binding site. Eur. J. Pharmacol. Mol. Pharm. 291:1995;319-325.
    • (1995) Eur. J. Pharmacol. Mol. Pharm. , vol.291 , pp. 319-325
    • Yang, W.1    Drewe, J.A.2    Lan, N.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.