Oral infection of C57BL/6 mice with Toxoplasma gondii: A new model of inflammatory bowel disease?

Journal of Infectious Diseases

Volumn 185, Issue SUPPL. 1, 2002, Pages

  Liesenfeld, Oliver ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; GAMMA INTERFERON; METRONIDAZOLE; NITRIC OXIDE SYNTHASE; SULFADIAZINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; CONFERENCE PAPER; CROHN DISEASE; ENTERITIS; IMMUNOPATHOGENESIS; IMMUNOPATHOLOGY; INTESTINE MUCOSA; INTESTINE VILLUS; MOUSE; MOUTH INFECTION; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TISSUE NECROSIS; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ADMINISTRATION, ORAL; ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATORY BOWEL DISEASES; MICE; MICE, INBRED C57BL; TOXOPLASMA; TOXOPLASMOSIS;

EID: 0037083246     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/338006     Document Type: Conference Paper

References (61)

1. Toxoplasmosis
2. Toxoplasmosis
3. Toxoplasmosis in the setting of AIDS
4. Bradyzoite-induced murine toxoplasmosis: Stage conversion, pathogenesis, and tissue formation in mice fed bradyzoites of different strains of Toxoplasma gondii
5. Oocyst-induced murine toxoplasmosis: Life cycle, pathogenicity, and stage conversion in mice fed Toxoplasma gondii oocysts
6. Immune response of mice to ingested Toxoplasma gondii: A model of toxoplasma infection acquired by ingestion
7. Detection of Toxoplasma gondii parasitemia by polymerase chain reaction in perorally infected mice
8. Early kinetics of Toxoplasma gondii infection in mice infected orally with cysts of an avirulent strain
9. Toxoplasma gondii: Blood and tissue kinetics during acute and chronic infection in mice
10. Interleukin-12, dendritic cells, and the initiation of host-protective mechanisms against Toxoplasma gondii
11. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection
12. Mucosal immune response in toxoplasmosis
13. Secretory IgA specific for Toxoplasma gondii
14. Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice
15. + gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes
16. Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii
17. Induction of gammadelta T cells during acute murine infection with Toxoplasma gondii
18. Immune responses associated with early survival after peroral infection with Toxoplasma gondii
19. + T cell-dependent, IFN-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii
20. Gamma interferon induces Fas-dependent apoptosis of Peyer's patch T cells in mice following peroral infection with Toxoplasma gondii
21. Strain-dependent, route of challenge-dependent, murine susceptibility to toxoplasmosis
22. Sex-determined resistance to Toxoplasma gondii is associated with temporal differences in cytokine production
23. Innate immunity to Toxoplasma gondii is influenced by the gender and is associated with differences in interleukin-12 and interferon-gamma production
24. Genetic resistance against acute toxoplasmosis depends on the strain of Toxoplasma gondii
25. TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected with Toxoplasma gondii
26. A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice
27. IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii
28. Murine ileitis after intracellular parasite infection is controlled by TGF-beta-producing intra-epithelial lymphocytes
29. Colitis in transgenic and knockout animals as models of human inflammatory bowel disease
30. Inflammatory bowel disease
31. Antibodies to interleukin 12 abrogate established experimental colitis in mice
32. The carrageenan model for experimental ulcerative colitis
33. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
34. Citrobacter rodentium infection in mice elicits a mucosal Th1 cytokine response and lesions similar to those in murine inflammatory bowel disease
35. Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
36. Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice
37. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
38. Interleukin-10-deficient mice develop chronic enterocolitis
39. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
40. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
41. + T cells
42. Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice
43. Targeted disruption of the mouse transforming growth factor-β gene results in multifocal inflammation
44. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of stat-3 in macrophages and neutrophils
45. A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
46. Altered development of intestinal intraepithelial lymphocytes in P-glycoprotein-deficient mice
47. Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T cell but not B cell activation
48. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice
49. Severe colitis in mice with aberrant thymic selection
50. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
51. Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa
52. Thymus dysfunction and chronic inflammatory disease in gp39 transgenic mice
53. Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice
54. Experimental models of inflammatory bowel disease
55. T cells in inflammatory bowel disease: Protective and pathogenic roles
56. Protective and pathogenic roles of cytokines in inflammatory bowel diseases
57. + lamina propria (LP) lymphocyte secretion profiles in inflammatory bowel disease
58. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
59. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
60. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
61. Oral toxoplasmosis: A murine model for human IBD?