메뉴 건너뛰기




Volumn 44, Issue 9, 1996, Pages 516-521

Protective and pathogenic roles of cytokines in inflammatory bowel diseases

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE;

EID: 0030341068     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (58)
  • 1
    • 0023146356 scopus 로고
    • The regulation of immune responses to dietary protein antigens
    • Mowat AM. The regulation of immune responses to dietary protein antigens. Immunol Today 1987;8:93-8.
    • (1987) Immunol Today , vol.8 , pp. 93-98
    • Mowat, A.M.1
  • 2
    • 0026633459 scopus 로고
    • Cells and cytokinos in mucosal immunity and inflammation
    • Beagley KW, Elson CO. Cells and cytokinos in mucosal immunity and inflammation. Gastroenterol Clin North Am 1992;21:347-66.
    • (1992) Gastroenterol Clin North Am , vol.21 , pp. 347-366
    • Beagley, K.W.1    Elson, C.O.2
  • 3
    • 0023871935 scopus 로고
    • Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T cell activation
    • Zeitz M, Greene WC, Petter NJ, James SP. Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T cell activation. Gastroenterology 1988;94:647-55.
    • (1988) Gastroenterology , vol.94 , pp. 647-655
    • Zeitz, M.1    Greene, W.C.2    Petter, N.J.3    James, S.P.4
  • 4
    • 0026432216 scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 1991;325:928-35.
    • (1991) N Engl J Med , vol.325 , pp. 928-935
    • Podolsky, D.K.1
  • 5
    • 0001947699 scopus 로고
    • Immunological diseases of the gastrointestinal tract
    • Rich RR, ed. St Louis: Mosby
    • Strober W, Neurath MF. Immunological diseases of the gastrointestinal tract. In: Rich RR, ed. Clinical Immunology. St Louis: Mosby, 1995:1401-28.
    • (1995) Clinical Immunology , pp. 1401-1428
    • Strober, W.1    Neurath, M.F.2
  • 6
    • 0025936625 scopus 로고
    • Reactivity of infiltrating T lymphocytes with microbial antigens in Crohn's disease
    • Pirzer U, Schonhaar A, Meyer zum Buschenfelde K-H, Fleischer B. Reactivity of infiltrating T lymphocytes with microbial antigens in Crohn's disease. Lancet 1991;338:1238-40.
    • (1991) Lancet , vol.338 , pp. 1238-1240
    • Pirzer, U.1    Schonhaar, A.2    Meyer Zum Buschenfelde, K.-H.3    Fleischer, B.4
  • 7
    • 0029993786 scopus 로고    scopus 로고
    • Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with IL-10 or antibodies to IL-12
    • Duchmann R, Schmitt E, Knolle P, Meyer zum Buschenfelde K-H, Neurath MF. Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with IL-10 or antibodies to IL-12. Eur J Immunol. 1996;26:934-8.
    • (1996) Eur J Immunol. , vol.26 , pp. 934-938
    • Duchmann, R.1    Schmitt, E.2    Knolle, P.3    Meyer Zum Buschenfelde, K.-H.4    Neurath, M.F.5
  • 8
  • 9
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horvak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-61.
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3    Schimpl, A.4    Feller, A.C.5    Horvak, I.6
  • 10
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993;75:263-74.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 12
    • 0028815073 scopus 로고
    • Definition of a lamina propria T cell responsive state. Enhanced cytokine responsiveness of T cells stimulated through the CD2 pathway
    • Targan SR, Deem RL, Liu M, Wang S, Nel A. Definition of a lamina propria T cell responsive state. Enhanced cytokine responsiveness of T cells stimulated through the CD2 pathway. J Immunol. 1995;154:664-75.
    • (1995) J Immunol. , vol.154 , pp. 664-675
    • Targan, S.R.1    Deem, R.L.2    Liu, M.3    Wang, S.4    Nel, A.5
  • 13
    • 0029681291 scopus 로고
    • Hypoproliferative human lamina propria T cells retain the capacity to secrete lymphokines when stimulated via CD2/CD28 signaling pathways
    • Boirivant M, Fuss I, Fiocchi C, Klein JS, Strong SA, Strober W. Hypoproliferative human lamina propria T cells retain the capacity to secrete lymphokines when stimulated via CD2/CD28 signaling pathways. Proc Assoc Am Physicians 1995;108:55-64.
    • (1995) Proc Assoc Am Physicians , vol.108 , pp. 55-64
    • Boirivant, M.1    Fuss, I.2    Fiocchi, C.3    Klein, J.S.4    Strong, S.A.5    Strober, W.6
  • 14
    • 4243359299 scopus 로고
    • Inflammatory bowel disease: Immunology of intestinal diseases
    • Shanahan F. Inflammatory bowel disease: immunology of intestinal diseases. Ann Intern Med 1987;106:853-66.
    • (1987) Ann Intern Med , vol.106 , pp. 853-866
    • Shanahan, F.1
  • 15
    • 0024260960 scopus 로고
    • Remission of Crohn's disease after human immunodeficiency virus infection
    • James SP. Remission of Crohn's disease after human immunodeficiency virus infection. Gastroenterology 1988;95:1667-76.
    • (1988) Gastroenterology , vol.95 , pp. 1667-1676
    • James, S.P.1
  • 16
    • 0005661911 scopus 로고
    • Cytokines and immune regulation
    • Rich RR, ed. St. Louis: Mosby
    • Mosmann T. Cytokines and immune regulation. In: Rich RR, ed. Clinical Immunology. St. Louis: Mosby, 1995:217-30.
    • (1995) Clinical Immunology , pp. 217-230
    • Mosmann, T.1
  • 17
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: TH1, TH2, and more
    • Mosmann T, Sad S. The expanding universe of T-cell subsets: TH1, TH2, and more. Immunol Today 1996;17:138-146.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.1    Sad, S.2
  • 19
    • 0028179230 scopus 로고
    • lo CD4+ T cells are important for the balance between protective and pithogenic cell-mediated immunity
    • lo CD4+ T cells are important for the balance between protective and pithogenic cell-mediated immunity. J Exp Med 1994;179:589-600.
    • (1994) J Exp Med , vol.179 , pp. 589-600
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3    Coffman, R.L.4
  • 20
    • 0027517545 scopus 로고
    • Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
    • Powrie F, Leach MW, Mauze S, Caddle LB, Coffman RL. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int Immunol 1993;5:1461-71.
    • (1993) Int Immunol , vol.5 , pp. 1461-1471
    • Powrie, F.1    Leach, M.W.2    Mauze, S.3    Caddle, L.B.4    Coffman, R.L.5
  • 21
    • 0029085294 scopus 로고
    • T cells in inflammatory bowel disease: Protective and pathogenic roles
    • Powrie F. T cells in inflammatory bowel disease: protective and pathogenic roles. Immunity 1995;3:171-4.
    • (1995) Immunity , vol.3 , pp. 171-174
    • Powrie, F.1
  • 22
    • 0027163182 scopus 로고
    • CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells
    • Morrissey PJ, Charrier K, Braddy S, Liggitt D, Watson JD. CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells. J Exp Med 1993;178:237-46.
    • (1993) J Exp Med , vol.178 , pp. 237-246
    • Morrissey, P.J.1    Charrier, K.2    Braddy, S.3    Liggitt, D.4    Watson, J.D.5
  • 23
    • 0030209985 scopus 로고    scopus 로고
    • The lymphokine production of lamina propria CD4+ T cells in Crohn's disease exhibits a TH1-like (IFN-γ) profile, whereas ulcerative colitis manifests a TH2-like (IL-5) profile
    • Fuss I, Neurath MF, Boirivant M, Klein JS, de la Motte C, Strong S, Fiocchi C, Strober W. The lymphokine production of lamina propria CD4+ T cells in Crohn's disease exhibits a TH1-like (IFN-γ) profile, whereas ulcerative colitis manifests a TH2-like (IL-5) profile. J Immunol 1996;157:1261-70.
    • (1996) J Immunol , vol.157 , pp. 1261-1270
    • Fuss, I.1    Neurath, M.F.2    Boirivant, M.3    Klein, J.S.4    De La Motte, C.5    Strong, S.6    Fiocchi, C.7    Strober, W.8
  • 25
    • 0026552488 scopus 로고
    • Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis
    • Mullin GE. Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis. Gastroenterology 1992;102:1620-7.
    • (1992) Gastroenterology , vol.102 , pp. 1620-1627
    • Mullin, G.E.1
  • 27
    • 0028969270 scopus 로고
    • Cytokine mRNA expression and proliferation status of intestinal mononuclear cells in noninflamed gut and Crohn's disease
    • Autschbach F, Schurmann G, Qiao L, Merz H, Wallich R, Meuer SC. Cytokine mRNA expression and proliferation status of intestinal mononuclear cells in noninflamed gut and Crohn's disease. Virchows Arch 1995;426:51-60.
    • (1995) Virchows Arch , vol.426 , pp. 51-60
    • Autschbach, F.1    Schurmann, G.2    Qiao, L.3    Merz, H.4    Wallich, R.5    Meuer, S.C.6
  • 30
    • 0028898529 scopus 로고
    • Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation
    • Casine RV, Kam L, Chong YJ, Fiocchi C, Pizarro TT, Cominelli F. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J Immunol 1995;154:2434-40.
    • (1995) J Immunol , vol.154 , pp. 2434-2440
    • Casine, R.V.1    Kam, L.2    Chong, Y.J.3    Fiocchi, C.4    Pizarro, T.T.5    Cominelli, F.6
  • 31
    • 0026709751 scopus 로고
    • Cytokine mRNA profiles in inflammatory bowel disease mucosa detected by PCR amplification
    • Isaaks KL, Sartor RB, Haskill S. Cytokine mRNA profiles in inflammatory bowel disease mucosa detected by PCR amplification. Gastroenterology 1992;103:1587-95.
    • (1992) Gastroenterology , vol.103 , pp. 1587-1595
    • Isaaks, K.L.1    Sartor, R.B.2    Haskill, S.3
  • 32
    • 0024344814 scopus 로고
    • Enhanced production of Interleukin1-β by mononuclear cells isolated from mucosa with active ulcerative colitis and Crohn's disease
    • Mahida YR, Wu K, Jewell DP. Enhanced production of Interleukin1-β by mononuclear cells isolated from mucosa with active ulcerative colitis and Crohn's disease. Gut 1989;30:835-8.
    • (1989) Gut , vol.30 , pp. 835-838
    • Mahida, Y.R.1    Wu, K.2    Jewell, D.P.3
  • 35
    • 0026607022 scopus 로고
    • Evidence for continuous stimulation of IL-6 production in Crohn's disease
    • Gross V, Andus T, Caesar I, Roth M, Scholmerich J. Evidence for continuous stimulation of IL-6 production in Crohn's disease. Gastroenterology 1992;102:514-9.
    • (1992) Gastroenterology , vol.102 , pp. 514-519
    • Gross, V.1    Andus, T.2    Caesar, I.3    Roth, M.4    Scholmerich, J.5
  • 36
    • 0027451455 scopus 로고
    • Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • Reinecker HC, Steffen M, Witthoeft T, Pflueger I, Schreiber S, MacDermott RP, Raedler A. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 1993;94:174-81.
    • (1993) Clin Exp Immunol , vol.94 , pp. 174-181
    • Reinecker, H.C.1    Steffen, M.2    Witthoeft, T.3    Pflueger, I.4    Schreiber, S.5    MacDermott, R.P.6    Raedler, A.7
  • 37
    • 0027422089 scopus 로고
    • Chronic intestinal inflammation: An unexpected outcome on cytokine or T cell receptor mutant mice
    • Strober W, Ehrhardt RO. Chronic intestinal inflammation: an unexpected outcome on cytokine or T cell receptor mutant mice. Cell 1993;75:203-5.
    • (1993) Cell , vol.75 , pp. 203-205
    • Strober, W.1    Ehrhardt, R.O.2
  • 39
    • 0025633436 scopus 로고
    • Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLAB-27-associated human disorders
    • Hammer RE, Maika SD, Richardson JA, Tang YP, Taurog JD. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: an animal model of HLAB-27-associated human disorders. Cell 1990;63:1099-112.
    • (1990) Cell , vol.63 , pp. 1099-1112
    • Hammer, R.E.1    Maika, S.D.2    Richardson, J.A.3    Tang, Y.P.4    Taurog, J.D.5
  • 41
    • 0028972499 scopus 로고
    • Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
    • Herminston ML, Gordon JI. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 1995;270:1203-7.
    • (1995) Science , vol.270 , pp. 1203-1207
    • Herminston, M.L.1    Gordon, J.I.2
  • 43
    • 0028861975 scopus 로고
    • Antibodies to IL-12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W. Antibodies to IL-12 abrogate established experimental colitis in mice. J Exp Med 1995;182:1281-90.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 44
    • 0006182054 scopus 로고    scopus 로고
    • Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of TH1-T cells through the inhibition of IL-12 secretion
    • Stuber E, Strober W, Neurath MF. Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of TH1-T cells through the inhibition of IL-12 secretion. J Exp Med 1996;183:183-9.
    • (1996) J Exp Med , vol.183 , pp. 183-189
    • Stuber, E.1    Strober, W.2    Neurath, M.F.3
  • 45
    • 0025167803 scopus 로고
    • Interleukin-1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis
    • Cominelli F. Interleukin-1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis. J Clin Invest 1990;86:972-80.
    • (1990) J Clin Invest , vol.86 , pp. 972-980
    • Cominelli, F.1
  • 49
    • 0026542168 scopus 로고
    • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor β after antigen-specific triggering
    • Miller A, Lider O. Roberts AB, Sporn MB, Weiner HL. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor β after antigen-specific triggering. Proc Natl Acad Sci USA 1992;89:421-5.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 421-425
    • Miller, A.1    Lider, O.2    Roberts, A.B.3    Sporn, M.B.4    Weiner, H.L.5
  • 50
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin-4, and prostaglandin E expression in the brain
    • Khoury SJ, Hancock WW, Weiner HL. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin-4, and prostaglandin E expression in the brain. J Exp Med 1992;176:1355-64.
    • (1992) J Exp Med , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 51
    • 0000253355 scopus 로고
    • Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen
    • Nagler-Anderson C, Bober A, Robinson M, Siskind G, Thorbecke G. Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen. Proc Natl Acad Sci USA 1983;83:7443-6.
    • (1983) Proc Natl Acad Sci USA , vol.83 , pp. 7443-7446
    • Nagler-Anderson, C.1    Bober, A.2    Robinson, M.3    Siskind, G.4    Thorbecke, G.5
  • 52
    • 0025347507 scopus 로고
    • Inhibition of S-antigen-induced experimental autoimmune uveoretinitis by oral induction of tolerance by S-antigen
    • Nussenblatt R, Caspi R, Mahdi R, Chan C, Roberge F, Lider O, Weiner HL. Inhibition of S-antigen-induced experimental autoimmune uveoretinitis by oral induction of tolerance by S-antigen. J Immunol 1989;144:1689-99.
    • (1989) J Immunol , vol.144 , pp. 1689-1699
    • Nussenblatt, R.1    Caspi, R.2    Mahdi, R.3    Chan, C.4    Roberge, F.5    Lider, O.6    Weiner, H.L.7
  • 53
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance
    • Neurath MF, Fuss I, Kelsall BL, Presky DH, Waegell W, Strober W. Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance. J Exp Med 1996;183:2605-16.
    • (1996) J Exp Med , vol.183 , pp. 2605-2616
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Presky, D.H.4    Waegell, W.5    Strober, W.6
  • 54
    • 0029165831 scopus 로고
    • Regulation by corticosteroids of TH1 and TH2 cytokine production in human CD4+ effector T cells generated from CD45RO- And CD45RO+ subsets
    • Brinkmann V, Kristofic C. Regulation by corticosteroids of TH1 and TH2 cytokine production in human CD4+ effector T cells generated from CD45RO- and CD45RO+ subsets. J Immunol 1995;155:3322-8.
    • (1995) J Immunol , vol.155 , pp. 3322-3328
    • Brinkmann, V.1    Kristofic, C.2
  • 55
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 1995;270:283-6.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 56
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκBα synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκBα synthesis. Science 1995;270:286-90.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 57
    • 0028907439 scopus 로고
    • Immunoregulatory role of interleukin-10 in patients with inflammatory bowel disease
    • Schreiber S, Heinig T, Thiele H-G, Raedler A. Immunoregulatory role of interleukin-10 in patients with inflammatory bowel disease. Gastroenterology 1995;108:1434-44.
    • (1995) Gastroenterology , vol.108 , pp. 1434-1444
    • Schreiber, S.1    Heinig, T.2    Thiele, H.-G.3    Raedler, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.