Oocyst-induced murine toxoplasmosis: Life cycle, pathogenicity, and stage conversion in mice fed Toxoplasma gondii oocysts

Journal of Parasitology

Volumn 83, Issue 5, 1997, Pages 870-882

  Dubey, J P ^b   Speer, C A ^a,b   Shen, S K ^b   Kwok, O C H ^b   Blixt, J A ^a,b  

^a MONTANA STATE UNIVERSITY   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; BRAIN INFECTION; CAT; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; INOCULATION; LIFE CYCLE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; OOCYST; PARASITE VIRULENCE; SMALL INTESTINE MUCOSA; SPOROZOITE; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; BIOLOGICAL ASSAY; BRAIN; CATS; INTESTINES; LIVER; LUNG; LYMPH NODES; MESENTERY; MICE; MICROSCOPY, ELECTRON; NECROSIS; PARASITEMIA; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL;

EID: 0030730793     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.2307/3284282     Document Type: Article

References (35)

1. BERTOLI, F., M. ESPINO, J. R. AROSEMENA, J. L. FISHBACK, AND J. K. FRENKEL. 1995. A spectrum in the pathology of toxoplasmosis in patients with acquired immunodeficiency syndrome. Archives of Pathology and Laboratory Medicine 119: 214-224.
2. BOHNE, W., J. HEESEMANN, AND U. GROSS. 1993. Induction of bradyzoite-specific Toxoplasma gondii antigens in gamma interferon-treated mouse macrophages. Infection and Immunity 61: 1141-1145.
3. CHINCHILLA, M., O. M. GUERRERO, G. CATARINELLA, AND L. REYES. 1993. Natural and induced blood dissemination of Toxoplasma gondii: Experimental model in white mice and hamsters. Revista de Biologia Tropical 41: 197-202.
4. DUBEY, J. P. 1983. Distribution of cysts and tachyzoites in calves and pregnant cows inoculated with Toxoplasma gondii oocysts. Veterinary Parasitology 13: 199-211.
5. _. 1984. Experimental toxoplasmosis in sheep fed Toxoplasma gondii oocysts. International Goat and Sheep Research 2: 93-104.
6. _. 1989. Lesions in goats fed Toxoplasma gondii oocysts. Veterinary Parasitology 32: 133-144.
7. _. 1995. Duration of immunity to shedding of Toxoplasma gondii oocysts by cats. Journal of Parasitology 81: 410-415.
8. _. 1996a. Pathogenicity and infectivity of Toxoplasma gondii oocysts for rats. Journal of Parasitology 82: 951-956.
9. _. 1996b. Infectivity and pathogenicity of Toxoplasma gondii oocysts for cats. Journal of Parasitology 82: 957-960.
10. _, AND C. P. BEATTIE. 1988. Toxoplasmosis of animals and man. CRC Press, Boca Raton, Florida, 220 p.
11. _, AND G. DESMONTS. 1987. Serological responses of equids fed Toxoplasma gondii oocysts. Equine Veterinary Journal 19: 337-339.
12. _, AND J. K. FRENKEL. 1973. Experimental Toxoplasma infection in mice with strains producing oocysts. Journal of Parasitology 59: 505-512.
13. _, AND _. 1976. Feline toxoplasmosis from acutely infected mice and the development of Toxoplasma cysts. Journal of Protozoology 23: 537-546.
14. _, M. A. GOODWIN, M. D. RUFF, O. C. H. KWOK, S. K. SHEN, G. C. WILKINS, AND P. THULLIEZ. 1994. Experimental toxoplasmosis in Japanese quail. Journal of Veterinary Diagnostic Investigation 6: 216-221.
15. _, _, _, S. K. SHEN, O. C. H. KWOK, G. L. WILKINS, AND P. THULLIEZ. 1995. Experimental toxoplasmosis in chukar partridges (Alecotoris graeca). Avian Pathology 24: 95-107.
16. _, J. K. LUNNEY, S. K. SHEN, O. C. H. KWOK, D. A. ASHFORD, AND P. THULLIEZ. 1996. Infectivity of low numbers of Toxoplasma gondii oocysts to pigs. Journal of Parasitology 82: 438-443.
17. FERGUSON, D. J. P., J. HUSKINSON-MARK, F. G. ARAUJO, AND J. S. REMINGTON. 1994. A morphological study of chronic cerebral toxoplasmosis in mice: Comparison of four different strains of Toxoplasma gondii. Parasitology Research 80: 493-501.
18. FRENKEL, J. K. 1996. The stage-conversion time of Toxoplasma gondii: Interpretation of chemical-biologic data out of parasitologic or host context. Parasitology Research 82: 656-658.
19. FREYRE, A., J. P. DUBEY, D. D. SMITH, AND J. K. FRENKEL. 1989. Oocyst-induced Toxoplasma gondii infections in cats. Journal of Parasitology 75: 750-755.
20. GROSS, U., W. BOHNE, M. SOÊTE, AND J. F. DUBREMENTZ. 1996. Developmental differentiation between tachyzoites and bradyzoites of Toxoplasma gondii. Parasitology Today 12: 30-33.
21. HOWE, D. K., AND L. D. SIBLEY. 1995. Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease. Journal of Infectious Diseases 172: 1561-1566.
22. JACOBS, L., J. S. REMINGTON, AND M. L. MELTON. 1960. The resistance of the encysted form of Toxoplasma gondii. Journal of Parasitology 46: 11-21.
23. LAINSON, R. 1958. Observations on the development and nature of pseudocysts and cysts of Toxoplasma gondii. Transactions of the Royal Society of Tropical Medicine and Hygiene 52: 396-407.
24. LANE, A., M. SOETE, J. E. DUBREMETZ, AND J. E. SMITH. 1996. Toxoplasma gondii: Appearance of specific markers during the development of tissue cysts in vitro. Parasitology Research 82: 340-346.
25. LINDSAY, D. S., AND J. P. DUBEY. 1989. Immunohistochemical diagnosis of Neospora caninum in tissue sections. American Journal of Veterinary Research 50: 1981-1983.
26. _, _, B. L. BLAGBURN, AND M. TOIVIO-KINNUCAN. 1991. Examination of tissue cyst formation by Toxoplasma gondii in cell cultures using bradyzoites, tachyzoites, and sporozoites. Journal of Parasitology 77: 126-132.
27. MCALLISTER, M. M., S. F. PARMLEY, L. M. WEISS, V. J. WELCH, AND A. M. MCGUIRE. 1996. An immunohistochemical method for detecting bradyzoite antigen (BAGS) in Toxoplasma gondii-infected tissue cross-reacts with a Neospora caninum bradyzoite antigen. Journal of Parasitology 82: 354-355.
28. ODAERT, H., M. SOÊTE, B. FORTIER, D. CAMUS, AND J. F. DUBREMETZ. 1996. Stage conversion of Toxoplasma gondii in mouse brain during infection and immunodepression. Parasitology Research 82: 28-31.
29. PARMLEY, S. F., U. GROSS, A. SUCHARCZUK, T. WINDECK, G. D. SAGARLATO, AND J. S. REMINGTON. 1994. Two alleles of the gene encoding surface antigen p22 in 25 strains of Toxoplasma gondii. Journal of Parasitology 80: 293-301.
30. RUIZ, A., AND J. K. FRENKEL. 1980. Intermediate and transport hosts of Toxoplasma gondii in Costa Rica. American Journal of Tropical Medicine and Hygiene 29: 1161-1166.
31. SHARMA, S. P., AND J. P. DUBEY. 1981. Quantitative survival of Toxoplasma gondii tachyzoites and bradyzoites in pepsin and in trypsin solutions. American Journal of Veterinary Research 42: 128-130.
32. SOÊTE, M., B. FORTIER, D. CAMUS, AND J. F. DUBREMETZ. 1993. Toxoplasma gondii: Kinetics of bradyzoite-tachyzoite interconversion in vitro. Experimental Parasitology 76: 259-264.
33. SPEER, C. A., J. P. DUBEY, J. A. BLIXT, AND K. PROKOP. 1997. Time lapse video microscopy and ultrastructure of penetrating sporozoites, types 1 and 2 parasitophorous vacuoles, and the transformation of sporozoites to tachyzoites of the VEG strain of Toxoplasma gondii. Journal of Parasitology 83: 564-574.
34. _, M. TILLEY, M. E. TEMPLE, J. A. BLIXT, J. P. DUBEY, AND M. W. WHITE. 1995. Sporozoites of Toxoplasma gondii lack dense-granule protein GRA3 and form a unique parasitophorous vacuole. Molecular and Biochemical Parasitology 75: 75-86.
35. WEISS, L. M., D. LAPLACE, P. M. TAKVORIAN, H. B. TANOWITZ, A. CALI, AND M. WITTNER. 1995. A cell culture system for study of the development of Toxoplasma gondii bradyzoites. Journal of Eukaryotic Microbiology 42: 150-157.