Functional integrity of mitochondrial genomes in human platelets and autopsied brain tissues from elderly patients with alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 2099-2103

  Ito, Sayaka ^a   Ohta, Shigeo ^b   Nishimaki, Kiyomi ^b   Kagawa, Yasuo ^c   Soma, Rika ^a   Kuno, Shin Ya ^a   Komatsuzaki, Yasuko ^d   Mizusawa, Hidehiro ^e   Hayashi, Jun Ichi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c Kochi Women's University   (Japan)

^d Hatsuishi Hospital   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; GENOME; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRION; MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; THROMBOCYTE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AUTOPSY; BLOOD PLATELETS; BRAIN; BRAIN CHEMISTRY; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; FEMALE; GLOBUS PALLIDUS; HELA CELLS; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; REFERENCE VALUES; SUBSTANTIA NIGRA; SYNAPTOSOMES; TRANSFECTION;

EID: 0033515075     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.2099     Document Type: Article

References (31)

1. Linnane, A. W., Marzuki, S., Ozawa, T. & Tanaka, M. (1989) Lancet i, 642-645.
2. Wallace, D. C. (1992) Science 256, 628-632.
3. Ames, B. N., Shigenaga, M. K. & Hagen, T. M. (1995) Biochim. Biophys. Acta 1271, 165-170.
4. Hayashi, J.-I., Ohta, S., Kagawa, Y., Kondo, H., Kaneda, H., Yonekawa, H., Takai, D. & Miyabayashi, S. (1994) J. Biol. Chem. 269, 6878-6883.
5. Soong, N. W., Hinton, D. R., Cortopassi, G. & Arnheim, N. (1992) Nat. Genet. 2, 318-323.
6. Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., Flint Beal, M. & Wallace, D. C. (1992) Nat. Genet. 2, 324-329.
7. Larson, N. G. & Clayton, D. A. (1995) Annu. Rev. Genet. 29, 151-178.
8. Hutchin, T. & Cortopassi, G. (1995) Proc. Natl. Acad. Sci. USA 92, 6892-6895.
9. Swerdlow, R. H., Parks, J. K., Miller, S. W., Tuttle, J. B., Trimmer, P. A., Sheehan, J. P., Bennett, J. P., Jr., Davis, R. E. & Parker, W. D., Jr. (1996) Ann. Neurol. 40, 663-671.
10. Davis, R. E., Miller, S., Herrnstadt, C., Ghosh, S. S., Fahy, E., Shinobu, L. A., Galasko, D., Thal, L. J., Beal, M. F., Howell, N., et al. (1997) Proc. Natl. Acad. Sci. USA 94, 4526-4531.
11. Sheehan, J. P., Swerdlow, R. H., Miller, S. W., Davis, R. E., Parks, J. K., Parker, W. D. & Tuttle, J. B. (1997) J. Neurosci. 17, 4612-4622.
12. Mattson, M. P. (1997) Trends Neurosci. 20, 373-375.
13. Isobe, K., Ito, S., Hosaka, H., Iwamura, Y., Kondo, H., Kagawa, Y. & Hayashi, J.-I. (1998) J. Biol. Chem. 273, 4601-4606.
14. Inoue, K., Ito, S., Takai, D., Soejima, A., Shisa, H., LePecq, J.-B., Segal-Bendirdjian, E., Kagawa, Y. & Hayashi, J.-I. (1997) J. Biol. Chem. 272, 15510-15515.
15. Soejima, A., Inoue, K., Takai, D., Kaneko, M., Ishihara, H., Oka, Y. & Hayashi, J.-I. (1996) J. Biol. Chem. 271, 26194-26199.
16. Inoue, K., Takai, D., Hosaka, H., Ito, S., Shitara, H., Isobe, K., LePecq, J.-B., Segal-Bendirdjian, E. & Hayashi, J.-I. (1997) Biochem. Biophys. Res. Commun. 239, 257-260.
17. Ito, S., Inoue, K., Yanagisawa, N., Kaneko, M. & Hayashi, J.-I. (1998) Biochem. Biophys. Res. Commun. 247, 432-435.
18. Hayashi, J.-I., Ohta, S., Kikuchi, A., Takemitsu, M., Goto, Y. & Nonaka, I. (1991) Proc. Natl. Acad. Sci. USA 88, 10614-10618.
19. Shitara, H., Hayashi, J.-I., Takahama, S., Kaneda, H. & Yonekawa, H. (1998) Genetics 148, 851-857.
20. Kubota, N., Hayashi, J.-I., Inada, T. & Iwamura, Y. (1997) Radiat. Res. 148, 395-398.
21. Newton, C. R., Graham, A., Heptinstall, L. E., Powell, S. J., Summers, C., Kalsheker, N., Smith, J. C. & Markham, A. F. (1989) Nucleic Acids Res. 17, 2503-2516.
22. Miyabayashi, S., Narisawa, K., Iinuma, K., Tada, K., Sakai, K., Kobayashi, K., Kobayashi, Y. & Morinaga, S. (1984) Brain Dev. 6, 362-372.
23. Schon, E. A., Rizzuto, R., Moraes, C. T., Nakase, H., Zeviani, M. & DiMauro, S. (1989) Science 244, 346-349.
24. Goto, Y., Nonaka, I. & Horai, S. (1990) Nature (London) 348, 651-653.
25. Hirano, M., Shtilbans, A., Mayeux, R., Davidson, M. M., DiMauro, S., Knowles, J. A. & Schon, E. A. (1997) Proc. Natl. Acad. Sci. USA 94, 14894-14899.
26. Wallace, D. C., Stugard, C., Murdock, D., Schurr, T. & Brown, M. D. (1997) Proc. Natl. Acad. Sci. USA 94, 14900-14905.
27. Mutisya, E. M., Bowling, A. C. & Beal, M. F. (1994) J. Neurochem. 63, 2179-2184.
28. Parker, W. D., Jr., Parks, J. K., Filley, C. M. & Kleinschmidt-DeMasters, B. K. (1994) Neurology 44, 1090-1096.
29. Hayashi, J.-I., Takemitsu, M., Goto, Y.-i. & Nonaka, I. (1994) J. Cell Biol. 125, 43-50.
30. Takai, D., Inoue, K., Goto, Y.-i., Nonaka, I. & Hayashi, J.-I. (1997) J. Biol. Chem. 272, 6028-6033.
31. Takai, D., Isobe, K. & Hayashi, J.-I. (1999) J. Biol. Chem., in press.