Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 26, 1997, Pages 14894-14899

  Hirano, Michio ^a,c   Shtilbans, Alexander ^a   Mayeux, Richard ^a,b   Davidson, Mercy M ^a   Dimauro, Salvatore ^a   Knowles, James A ^a,b   Schon, Eric A ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

^b Vagelos College of Physicians and Surgeons   (United States)

^c Department of Orthopaedic Surgery   (United States)

Author keywords

Cytochrome c oxidase; Mitochondria; Oxidative phosphorylation; Respiratory chain

Indexed keywords

CYTOCHROME C OXIDASE; DNA; MITOCHONDRIAL DNA;

ALZHEIMER DISEASE; ARTICLE; ARTIFACT; CONTROLLED STUDY; DNA SEQUENCE; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOGENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SOUTHERN BLOTTING;

ADULT; ALZHEIMER DISEASE; CELL NUCLEUS; DNA, MITOCHONDRIAL; HUMANS; POLYMERASE CHAIN REACTION; PSEUDOGENES;

EID: 0031449003     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.26.14894     Document Type: Article

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