Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells

International Journal of Cancer

Volumn 99, Issue 2, 2002, Pages 292-298

  Ruefli, Astrid A ^a   Bernhard, David ^b   Tainton, Kellie M ^a   Kofler, Reinhard ^b   Smyth, Mark J ^c   Johnstone, Ricky W ^a  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c NONE

Author keywords

Apoptosis; Chemotherapy; Histone deacetylase; Multidrug resistance; P glycoprotein

Indexed keywords

CASPASE; COMPLEMENT; CYTOCHROME C; GLYCOPROTEIN P; GRANZYME B; HISTONE DEACETYLASE INHIBITOR; PERFORIN; PNEUMOLYSIN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RECEPTOR; VORINOSTAT;

APOPTOSIS; ARTICLE; CANCER CELL; CELL PROTECTION; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DEACETYLATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; OXIDATIVE STRESS; PRIORITY JOURNAL; ULTRAVIOLET IRRADIATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASES; CELL CYCLE; CELL DEATH; CHROMIUM RADIOISOTOPES; COLONIC NEOPLASMS; CYTOCHROME C GROUP; DRUG RESISTANCE, MULTIPLE; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LEUKEMIA, T-CELL; P-GLYCOPROTEIN; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED; VINCRISTINE;

EID: 0037052687     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10327     Document Type: Article

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