-
1
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman M, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem. 1993;62:385.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385
-
-
Gottesman, M.1
Pastan, I.2
-
2
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins CF. ABC transporters: from microorganisms to man. Annu Rev Cell Biol. 1992;8:67.
-
(1992)
Annu Rev Cell Biol
, vol.8
, pp. 67
-
-
Higgins, C.F.1
-
3
-
-
0027458116
-
ATP-dependent transport systems in bacteria and humans: Relevance to cystic fibrosis and multidrug resistance
-
Doige CA, Ames FG. ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance. Annu Rev Microbiol. 1993;47:291.
-
(1993)
Annu Rev Microbiol
, vol.47
, pp. 291
-
-
Doige, C.A.1
Ames, F.G.2
-
4
-
-
0032499771
-
The drug efflux protein, P-glycoprotein, additionally protects drug-resistant cells from multiple forms of caspase-dependent apoptosis
-
Smyth MJ, Krasovskis E, Sutton VR, Johnstone RW. The drug efflux protein, P-glycoprotein, additionally protects drug-resistant cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci U S A. 1998;95:7024.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7024
-
-
Smyth, M.J.1
Krasovskis, E.2
Sutton, V.R.3
Johnstone, R.W.4
-
5
-
-
0032950954
-
P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death
-
Johnstone RW, Cretney E, Smyth MJ. P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death. Blood. 1999;93:1075.
-
(1999)
Blood
, vol.93
, pp. 1075
-
-
Johnstone, R.W.1
Cretney, E.2
Smyth, M.J.3
-
6
-
-
0030964625
-
Human MDR1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts
-
Robinson U, Roberts WK, Ling TT, Lamming D, Sternberg SS, Roepe, PD. Human MDR1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts. Biochemistry. 1997;36:11,169.
-
(1997)
Biochemistry
, vol.36
-
-
Robinson, U.1
Roberts, W.K.2
Ling, T.T.3
Lamming, D.4
Sternberg, S.S.5
Roepe, P.D.6
-
7
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell. 1996;85:803.
-
(1996)
Cell
, vol.85
, pp. 803
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
8
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/ APO-1) death-inducing signaling complex
-
Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/ APO-1) death-inducing signaling complex. Cell. 1996;85:872.
-
(1996)
Cell
, vol.85
, pp. 872
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
-
9
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula SM, Ahmad M, Fernades-Alnemri T, Litwack G, Alnemri ES. Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci U S A. 1996;93:14,486.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernades-Alnemri, T.3
Litwack, G.4
Alnemri, E.S.5
-
10
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 1996;86:147.
-
(1996)
Cell
, vol.86
, pp. 147
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
11
-
-
0031037897
-
The release of cylochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cylochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science. 1997;275:1132.
-
(1997)
Science
, vol.275
, pp. 1132
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
12
-
-
0030782177
-
Cytochrome c: Can't live with it - Can't live without it
-
Reed JC. Cytochrome c: can't live with it - can't live without it. Cell. 1997;91:559.
-
(1997)
Cell
, vol.91
, pp. 559
-
-
Reed, J.C.1
-
13
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature. 1999;397:441.
-
(1999)
Nature
, vol.397
, pp. 441
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
14
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91:479.
-
(1997)
Cell
, vol.91
, pp. 479
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
15
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 1997;90: 405.
-
(1997)
Cell
, vol.90
, pp. 405
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
16
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu C, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 1997;94:491.
-
(1997)
Cell
, vol.94
, pp. 491
-
-
Li, H.1
Zhu, H.2
Xu, C.3
Yuan, J.4
-
17
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 1997;94:481.
-
(1997)
Cell
, vol.94
, pp. 481
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
18
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 1997;275:1129.
-
(1997)
Science
, vol.275
, pp. 1129
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
19
-
-
0032561352
-
Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent
-
Trapani JA, Jans DA, Jans PJ, Smyth MJ, Browne KA, Sutton VR. Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent. J Biol Chem. 1997;273: 27934.
-
(1997)
J Biol Chem
, vol.273
, pp. 27934
-
-
Trapani, J.A.1
Jans, D.A.2
Jans, P.J.3
Smyth, M.J.4
Browne, K.A.5
Sutton, V.R.6
-
20
-
-
0032193209
-
Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes
-
Deas O, Dumont C, MacFarlane M, et al. Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes. J Immunol. 1997;161:3375.
-
(1997)
J Immunol
, vol.161
, pp. 3375
-
-
Deas, O.1
Dumont, C.2
MacFarlane, M.3
-
21
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel E, Newmeyer DD, Green DR. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 1998; 17:37.
-
(1998)
EMBO J
, vol.17
, pp. 37
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
22
-
-
0032545372
-
Bcl-2 prevents caspase-independent cell death
-
Okuno S, Shimizu S, Ito T, et al. Bcl-2 prevents caspase-independent cell death. J Biol Chem. 1998;273:34,272.
-
(1998)
J Biol Chem
, vol.273
-
-
Okuno, S.1
Shimizu, S.2
Ito, T.3
-
23
-
-
0031570536
-
Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes
-
Sutton VR, Vaux OL, Trapani JA. Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes. J Immunol. 1997;158:783.
-
(1997)
J Immunol
, vol.158
, pp. 783
-
-
Sutton, V.R.1
Vaux, O.L.2
Trapani, J.A.3
-
24
-
-
0030745314
-
Two cytodifferentiation agent-induced pathways, differentiation and apoptosis, are distinguished by the expression of human papillomavirus 16 E7 in human bladder carcinoma cells
-
Richon VM, Russo P, Venta-Perez G, Cordon-Cardo C, Rifkind RA, Marks PA. Two cytodifferentiation agent-induced pathways, differentiation and apoptosis, are distinguished by the expression of human papillomavirus 16 E7 in human bladder carcinoma cells. Cancer Res. 1997;57: 2789.
-
(1997)
Cancer Res
, vol.57
, pp. 2789
-
-
Richon, V.M.1
Russo, P.2
Venta-Perez, G.3
Cordon-Cardo, C.4
Rifkind, R.A.5
Marks, P.A.6
-
25
-
-
0028116705
-
Inducing differentiation of transformed cells with hybrid polar compounds: A cell cycle-dependent process
-
Marks PA, Richon VM, Kiyokawa H, Rifkind RA. Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process. Proc Natl Acad Sci U S A. 1994;91:10,251.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
-
-
Marks, P.A.1
Richon, V.M.2
Kiyokawa, H.3
Rifkind, R.A.4
-
26
-
-
0026446246
-
Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: A phase II clinical trial with a differentiation-inducing agent
-
Andreef M, Stone R, Michaeli J, et al. Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: a phase II clinical trial with a differentiation-inducing agent. Blood. 1992;80:2604.
-
(1992)
Blood
, vol.80
, pp. 2604
-
-
Andreef, M.1
Stone, R.2
Michaeli, J.3
-
27
-
-
0028080878
-
Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells
-
Kiyokawa H, Richon VM, Ritkind RA, Marks PA. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Mol Cell Biol. 1994;11:7195.
-
(1994)
Mol Cell Biol
, vol.11
, pp. 7195
-
-
Kiyokawa, H.1
Richon, V.M.2
Ritkind, R.A.3
Marks, P.A.4
-
28
-
-
0032005979
-
Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line
-
Yamashita T, Wakao H, Miyajima A, Asano S. Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line. Cancer Res. 1998;58:556.
-
(1998)
Cancer Res
, vol.58
, pp. 556
-
-
Yamashita, T.1
Wakao, H.2
Miyajima, A.3
Asano, S.4
-
29
-
-
0031892734
-
Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells
-
Siegel DS, Zhang X, Feinman R, et al. Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells. Proc Natl Acad Sci U S A. 1998;95:162.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 162
-
-
Siegel, D.S.1
Zhang, X.2
Feinman, R.3
-
30
-
-
0028356225
-
Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line
-
Zalcberg JR, Hu XF, Wall DM, et al. Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line. Int J Cancer. 1994; 57:522.
-
(1994)
Int J Cancer
, vol.57
, pp. 522
-
-
Zalcberg, J.R.1
Hu, X.F.2
Wall, D.M.3
-
31
-
-
0024208685
-
Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline
-
Broggini M, Grandi M, Ubezio P, Geroni C, Giuliani FC, D'Incalci M. Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline. Biochem Pharmacol. 1988;37:4423.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 4423
-
-
Broggini, M.1
Grandi, M.2
Ubezio, P.3
Geroni, C.4
Giuliani, F.C.5
D'Incalci, M.6
-
32
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr I, Wilhelm D, Bohler T, Angel P, Debatin K-M. Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J. 1997;16:6200.
-
(1997)
EMBO J
, vol.16
, pp. 6200
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.-M.5
-
33
-
-
0031847334
-
Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction
-
Trapani JA, Jans P, Smyth MJ, et al. Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction. Cell Death Diff. 1998;5: 488.
-
(1998)
Cell Death Diff
, vol.5
, pp. 488
-
-
Trapani, J.A.1
Jans, P.2
Smyth, M.J.3
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248.
-
(1976)
Anal Biochem
, vol.72
, pp. 248
-
-
Bradford, M.M.1
-
35
-
-
0033521626
-
Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis
-
MacDonald G, Shi L, Vande Velde C, Lieberman J, Greenberg AH. Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis. J Exp Med. 1999;189:131.
-
(1999)
J Exp Med
, vol.189
, pp. 131
-
-
MacDonald, G.1
Shi, L.2
Vande Velde, C.3
Lieberman, J.4
Greenberg, A.H.5
-
36
-
-
0029125701
-
Protease activation during apoptosis: Death by a thousand cuts?
-
Martin SJ, Green DR. Protease activation during apoptosis: death by a thousand cuts? Cell. 1995; 82:349.
-
(1995)
Cell
, vol.82
, pp. 349
-
-
Martin, S.J.1
Green, D.R.2
-
37
-
-
0017061205
-
The sensitivity of chromatin from thymuses and spleens of irradiated mice to alkaline solutions
-
Skalka M, Matyasova J, Cejkova M. The sensitivity of chromatin from thymuses and spleens of irradiated mice to alkaline solutions. FEBS Lett. 1976;72:271.
-
(1976)
FEBS Lett
, vol.72
, pp. 271
-
-
Skalka, M.1
Matyasova, J.2
Cejkova, M.3
-
38
-
-
0018830636
-
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
-
Wyllie AH. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature. 1980;284:555.
-
(1980)
Nature
, vol.284
, pp. 555
-
-
Wyllie, A.H.1
-
40
-
-
0032498630
-
E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk
-
Lavoie JN, Nguyen M, Marcellus RC, Branton PE, Shore GC. E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk. J Cell Biol. 1998;140:637.
-
(1998)
J Cell Biol
, vol.140
, pp. 637
-
-
Lavoie, J.N.1
Nguyen, M.2
Marcellus, R.C.3
Branton, P.E.4
Shore, G.C.5
-
41
-
-
0030863670
-
Requirement for the GD3 ganglioside in CD95- and ceramide-induced apoptosis
-
De Maria R, Lenti L, Malisan F, et al. Requirement for the GD3 ganglioside in CD95- and ceramide-induced apoptosis. Science. 1997;277:1652.
-
(1997)
Science
, vol.277
, pp. 1652
-
-
De Maria, R.1
Lenti, L.2
Malisan, F.3
-
42
-
-
0030797727
-
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
-
Miller TM, Moulder KL, Knudson CM, et al. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J Cell Biol. 1997;139:205.
-
(1997)
J Cell Biol
, vol.139
, pp. 205
-
-
Miller, T.M.1
Moulder, K.L.2
Knudson, C.M.3
-
43
-
-
0032546795
-
Caspase-3 is required for α-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
-
Janicke RU, Ng P, Sprengart ML, Porter AG. Caspase-3 is required for α-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J Biol Chem. 1998;275:15,540.
-
(1998)
J Biol Chem
, vol.275
-
-
Janicke, R.U.1
Ng, P.2
Sprengart, M.L.3
Porter, A.G.4
-
44
-
-
0030806351
-
Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
-
Eischen CM, Kottke TJ, Martins LM, et al. Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood. 1997;90:935.
-
(1997)
Blood
, vol.90
, pp. 935
-
-
Eischen, C.M.1
Kottke, T.J.2
Martins, L.M.3
-
45
-
-
0032533599
-
Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53
-
Byrd JC, Shinn C, Waselenko JK, et al. Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53. Blood. 1998;92:3804.
-
(1998)
Blood
, vol.92
, pp. 3804
-
-
Byrd, J.C.1
Shinn, C.2
Waselenko, J.K.3
-
46
-
-
0032588672
-
Bcl-XL induction during terminal differentiation of friend erythroleukemia cells correlates with delay in apoptosis and loss of proliferative capacity but not haemoglobinization
-
Hafid-Medheb K, Poindessous-Jazat V, Augery-Bourget Y, Hanania N, Robert-Lezenes J. Bcl-XL induction during terminal differentiation of friend erythroleukemia cells correlates with delay in apoptosis and loss of proliferative capacity but not haemoglobinization. Cell Death Differ. 1999;6: 166.
-
(1999)
Cell Death Differ
, vol.6
, pp. 166
-
-
Hafid-Medheb, K.1
Poindessous-Jazat, V.2
Augery-Bourget, Y.3
Hanania, N.4
Robert-Lezenes, J.5
-
47
-
-
1542588471
-
Second generation hybrid polar compounds are potent inducers of transformed cell differentiation
-
Richon VM, Webb Y, Merger R, et al. Second generation hybrid polar compounds are potent inducers of transformed cell differentiation. Proc Natl Acad Sci U S A. 1996;93:5705.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5705
-
-
Richon, V.M.1
Webb, Y.2
Merger, R.3
|