Selective inhibition of heterotrimeric Gs signaling: Targeting the receptor-G protein interface using a peptide minigene encoding the Gαs carboxyl terminus

Journal of Biological Chemistry

Volumn 277, Issue 32, 2002, Pages 28631-28640

  Feldman, David S ^a,c   Zamah, A Musa ^a   Pierce, Kristen L ^a   Miller, William E ^a   Kelly, Francine ^a   Rapacciuolo, Antonio ^a   Rockman, Howard A ^a   Koch, Walter J ^a   Luttrell, Louis M ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; CELL MEMBRANES; ENZYME INHIBITION; ENZYMES; GENES; POLYPEPTIDES;

CELLULAR RESPONSE; GENE EXPRESSION; HEPTAHELICAL RECEPTORS; PROTEIN KINASE;

PROTEINS;

ADENYLATE CYCLASE; AMINO ACID; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 1 RECEPTOR; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL; POLYPEPTIDE; PROTEIN INHIBITOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; SULFUR 35; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CERCOPITHECIDAE; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; HYDROLYSIS; ISOTOPE LABELING; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; BINDING COMPETITION; BIOLOGICAL MODEL; CELL DIVISION; CELL LINE; CELL STRAIN COS1; CHEMISTRY; DIMERIZATION; DOSE RESPONSE; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; CERCOPITHECIDAE;

ANIMALS; BINDING, COMPETITIVE; CELL DIVISION; CELL LINE; COS CELLS; CYCLIC AMP; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; HUMANS; HYDROLYSIS; ISOPROTERENOL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; PEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 0037047292     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204753200     Document Type: Article

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