Telomeres, telomerase, and cancer

New England Journal of Medicine

Volumn 342, Issue 17, 2000, Pages 1282-1283

  Buys, Charles H C M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED DNA POLYMERASE; TELOMERASE;

ARTICLE; CANCER RESEARCH; CHROMOSOME REPLICATION; DNA REPLICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TELOMERE;

CELL DIVISION; DNA-BINDING PROTEINS; HUMANS; MUTATION; NEOPLASMS; RNA; TELOMERASE; TELOMERE; TUMOR CELLS, CULTURED;

EID: 0034720245     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200004273421710     Document Type: Article

References (5)

1. Hahn WC, Stewart SA, Brooks MW, et al. Inhibition of telomerase limits the growth of human cancer cells. Nat Med 1999;5:1164-70.
2. Zhang X, Mar V, Zhou W, Harrington L, Robinson MO. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev 1999;13:2388-99.
3. Herbert B-S, Pitts AE, Baker SI, et al. Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proc Natl Acad Sci U S A 1999;96:14276-81.
4. Remes K, Norrback KF, Rosenquist R, Mehle C, Lindh J, Roos G. Telomerc length and telomerase activity in malignant lymphomas at diagnosis and relapse. Br J Cancer 2000;82:601-7.
5. Rudolph KL, Chang S, Millard M, Schreiber-Agus N, DePinho RA. Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science 2000;287:1253-8.