The Conserved Active Site Motif A of Escherichia coli DNA Polymerase I is Highly Mutable

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 18836-18842

  Shinkai, Akeo ^b   Patel, Premal H ^b   Loeb, Lawrence A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; DNA; ENZYME KINETICS; ESCHERICHIA COLI; GENETIC ENGINEERING; MUTAGENESIS;

ACTIVE SITES;

BIOCHEMISTRY;

AMINO ACID; ARGININE; DNA DIRECTED DNA POLYMERASE BETA; ISOLEUCINE; NUCLEOTIDE; RNA; SINGLE STRANDED DNA; VALINE; ASPARTIC ACID;

ARTICLE; BACTERIAL GROWTH; DNA REPAIR; DNA REPLICATION; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME ASSAY; ESCHERICHIA COLI; KINETICS; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; BINDING SITE; CATALYSIS; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ASPARTIC ACID; BINDING SITES; CATALYSIS; CONSERVED SEQUENCE; DNA POLYMERASE I; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; ISOLEUCINE; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; MUTATION; RNA; SEQUENCE ANALYSIS, DNA;

EID: 0035374671     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011472200     Document Type: Article

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