RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: Involvement of metalloproteases

Oncogene

Volumn 18, Issue 33, 1999, Pages 4718-4725

  Aguirre Ghiso, Julio A ^a,d   Frankel, Paul ^b   Farias, Eduardo F ^a   Lu, Zhimin ^b   Jiang, Hong ^b,e   Olsen, Amanda ^b   Feig, Larry A ^c   Bal De Kier Joffe, Elisa ^a   Foster, David A ^b  

^a Instituto de Oncologia Angel H Roffo   (Argentina)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

GTPase; Metalloproteases; Ral; Ras; Src; Tumorigenicity; uPA

Indexed keywords

GUANOSINE TRIPHOSPHATASE; METALLOPROTEINASE; PHOSPHOLIPASE D; PLASMINOGEN ACTIVATOR; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CARCINOGENICITY; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; CORRELATION FUNCTION; DOMINANT GENE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; GENETIC REGULATION; GENETIC TRANSFORMATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOGENESIS; MOUSE; ONCOGENE RAS; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZYMOGRAPHY;

3T3 CELLS; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; COLLAGENASES; GELATINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; GENES, SRC; GTP PHOSPHOHYDROLASES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; MUTATION; RAL GTP-BINDING PROTEINS; UP-REGULATION; URINARY PLASMINOGEN ACTIVATOR;

ANIMALIA;

EID: 0009374793     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202850     Document Type: Article

References (41)

1. Aguirre-Ghiso JA, Alonso DF, Farias EF and Bal de Kier Joffe E. (1997). Biochim. Biophys. Acta, 1356, 171-184.
2. Alonso DF, Farias EF and Bal de Kier Joffe E. (1993). Cancer Letts., 70, 181-187.
3. Bell SM, Connolly DC, Maihle NJ and Degen JL. (1993). Mol. Cell. Biol., 13, 5888-5897.
4. Bi K, Roth MG and Ktikstakis NT. (1997). Curr. Biol., 7, 301-307.
5. Blobe GC, Obeid ML and Hannun YA. (1994). Cancer Meta. Rev., 13, 411-431
6. Boyd D. (1996). Cancer Meta. Rev., 15, 77-89.
7. Burgering BMT and Bos JL. (1995). TIBS, 20, 18-22.
8. Carmeliet P, Moons L, Lijnen R, Baes M, Lemaitre V, Tipping P, Drew A, Eckhout Y, Shapiro S, Lupu F and Collen D. (1997). Nat. Genet., 17, 439-444.
9. Carpenter CL and Cantley LC. (1996). Biochim. Biophys. Acta, 1288, M11-M16.
10. Exton JH. (1994). Biochim. Biophys. Acta, 1212, 26-42.
11. Exton JH. (1998). Biochim. Biophys. Acta, 1436, 105-115.
12. Foster DA. (1993). Cell Signalling, 5, 389-399.
13. Gum R, Lengyel E, Juarez J, Chen JH, Sieki M and Boyd D. (1996). J. Biol. Chem., 271, 10672-10680.
14. Gum R, Wang H, Lengyel E, Juarez J and Boyd D. (1997). Oncogene, 14, 1481-1493.
15. Hart IR, Goode NT and Wilson RE. (1989). Biochim. Biophys. Acta, 989, 65-84.
16. Jiang H, Lu Z, Luo JQ. Wolfman A and Poster DA. (1995a). J. Biol. Chem., 270, 6006-6009.
17. Jiang H, Luo J-Q, Urano T, Frankel P, Lu Z, Foster DA and Feig LA. (1995b). Nature, 378, 409-412.
18. Lengyel E, Gum R, Stepp E, Juarez J, Wang H and Boyd D. (1996). J. Cell. Biochem., 61, 430-443.
19. Lengyel E, Wang H, Gum R, Simon C, Wang Y and Boyd D. (1997). Oncogene, 14, 2563-2573.
20. Liotta LA and Stetler-Stevenson WG. (1991). Cancer Res., 51, 5054-5059.
21. Liotta LA, Steeg PS and Stetler-Stevenson W. (1991). Cell, 64, 327-336.
22. Luo J-Q, Liu X, Frankel P, Rotunda T, Ramos M, Flom J, Jiang H, Feig LA, Morris A, Kahn RA and Foster DA. (1998). Proc. Natl. Acad. Sci. USA, 95, 3632-3637.
23. Luo J-Q, Liu X, Hammond SM, Colley WC, Feig LA, Frohman MA, Morris AJ and Foster DA. (1997). Biochem. Biophys. Res. Comm., 235, 854-859.
24. Matrisian LM. (1992). BioEsaays, 14, 455-463.
25. Mazzieri R, Masiero L, Zanetta L, Monea S, Onisto M, Garbisa S and Mignatti P. (1997). EMBO J., 16, 2319-2332.
26. Moller LB. (1993). Blood Coagul. Fibrinol., 4, 293-303.
27. Ossowski L. (1992). Cancer Res., 52, 6754-6760.
28. Ossowski L and Reich E. (1983). Cell, 35, 611-619.
29. Pittman RN. (1985). Dev. Biol., 110, 91-101.
30. Qureshi SA, Joseph CK, Gupta R. Hendriekson M, Song J, Bruder J, Rapp U and Foster DA. (1993). Biochem. Biophys. Res. Comm., 192, 969-975.
31. Reich R, Blumenthal M and Liscovitch M. (1995). Clin. Exp. Meta., 13, 134-140.
32. Roth MG and Sternweis PC. (1997). Curr. Opin. Cell. Biol., 9, 519-526.
33. Saksela O. (1981). Anal. Biochem., 111, 276-282.
34. Sato H, Kita M and Seiki M. (1993). J. Biol. Chem., 268, 23460-23468.
35. Silberman S, Janulis M and Schultz RM. (1997). J. Biol. Chem., 272, 5927-5935.
36. Song J, Pfeffer LM and Foster DA. (1991). Mol. Cell. Biol., 11, 4903-4908.
37. Urano T, Emkey R and Feig LA. (1996). EMBO J., 15, 810-816.
38. Werb Z, Ashkenas J, MacAuley A and Wiesen JF. (1996). Braz. J. Med. Biol. Res., 29, 1087-1097.
39. Williger B-T, Ho W-T and Exton JH. (1999). J. Biol. Chem., 274, 735-738.
40. Yu H and Schultz RM. (1990). Cancer Res., 50, 7623-7633.
41. Yu W, Kim J and Ossowski L. (1997). J. Cell. Biol., 137, 767-777.