Characterization of the role of the "MT-loop": An eight-amino acid insertion specific to progelatinase A (MMP2) activating membrane-type matrix metalloproteinases

Journal of Biological Chemistry

Volumn 276, Issue 45, 2001, Pages 42018-42026

  English, William R ^a   Holtz, Béatrice ^b   Vogt, Gavin ^a   Knäuper, Vera ^c   Murphy, Gillian ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b DIF   (France)

^c UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; CELLS; ENZYME KINETICS; TOPOLOGY;

MUTANTS;

ENZYMES;

AMINO ACID; ENZYME PRECURSOR; FIBRINOGEN; GELATINASE A; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 15; MATRIX METALLOPROTEINASE 16; MATRIX METALLOPROTEINASE 24; MUTANT PROTEIN; PEPTIDE; PROGELATINASE A; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; GELATINASE; METALLOPROTEINASE; PROGELATINASE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; GENE DELETION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; HAMSTER; METABOLISM; PHYSIOLOGY; PROTEIN FOLDING;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; INSERTION SEQUENCES;

ANIMALS; CATALYTIC DOMAIN; CHO CELLS; CRICETINAE; ENZYME ACTIVATION; ENZYME PRECURSORS; FIBRINOGEN; GELATINASES; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; PROTEIN FOLDING; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 0035834666     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107783200     Document Type: Article

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