Metagenome - A challenging source of enzyme discovery

Journal of Molecular Catalysis B: Enzymatic

Volumn 19-20, Issue , 2002, Pages 13-19

  Lorenz, Patrick ^a   Schleper, Christa ^b,c  

^a BRAIN AG   (Germany)

^b DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^c Zentrum für Molekulare Evolution und Biodiversität ZEB   (Germany)

Author keywords

Biocatalysis; Enzyme; Metagenome; Microorganism; Uncultivated biodiversity

Indexed keywords

CLONING; DNA; GENES; METABOLISM; MICROORGANISMS; PHYSIOLOGY; SCREENING;

MOLECULAR ECOLOGICAL STUDIES;

ENZYMES;

AMYLASE; DEOXYRIBONUCLEASE; DNA; ESTERASE; MICROBIAL ENZYME; OXIDOREDUCTASE; OXYGENASE; PROTEINASE; TRIACYLGLYCEROL LIPASE;

CELL CULTURE; CONFERENCE PAPER; DNA ISOLATION; DNA VECTOR; GENE LIBRARY; GENE SEQUENCE; GENETIC VARIABILITY; MICROBIAL GENETICS; MICROFLORA; MICROORGANISM; MOLECULAR CLONING;

EID: 0037010721     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(02)00147-9     Document Type: Conference Paper

References (33)

1. Pace N.R. Science. 276:1997;734.
2. Whitman W.B., Coleman D.C., Wiebe W.J. Proc. Natl. Acad. Sci. U.S.A. 95:1998;6578.
3. K. Faber, Biotransformations in Organic Chemistry - A Textbook, Springer, Berlin, Heidelberg, New York, 2001.
4. Schmid A., Dordick J.S., Hauer B., Kiener A., Wubbolts M., Witholt B. Nature. 409:2001;258.
5. Staley J.T., Konopka A. Annu. Rev. Microbiol. 39:1985;321.
6. Pace N.R., Stahl D.A., Lane D.J., Olsen G.J. Adv. Microb. Ecol. 9:1986;1.
7. Hugenholtz P., Goebel B.M., Pace N.R. J. Bacteriol. 180:1998;4765.
8. Amann R.I., Ludwig W., Schleifer K.H. Microbiol. Rev. 59:1995;143.
9. DeLong E.F. Curr. Opin. Genet. Dev. 8:1998;649.
10. Handelsman J., Rondon M.R., Brady S.F., Clardy J., Goodman R.M. Chem. Biol. 5:1998;R245.
11. Steffan R.J., Goksoyr J., Bej A.K., Atlas R.M. Appl. Environ. Microbiol. 54:1988;2908.
12. Schmidt T., DeLong E., Pace N. J. Bacteriol. 173:1991;4371.
13. Stein J.L., Marsh T.L., Wu K.Y., Shizuya H., DeLong E.F. J. Bacteriol. 178:1996;591.
14. Schleper C., DeLong E.F., Preston C.M., Feldman R.A., Wu K.Y., Swanson R.V. J. Bacteriol. 180:1998;5003.
15. Beja O., Suzuki M.T., Koonin E.V., Aravind L., Hadd A., Nguyen L.P., Villacorta R., Amjadi M., Garrigues C., Jovanovich S.B., Feldman R.A., DeLong E.F. Environ. Microbiol. 2:2000;516.
16. Henne A., Daniel R., Schmitz R.A., Gottschalk G. Appl. Environ. Microbiol. 65:1999;3901.
17. Rondon M.R., August P.R., Bettermann A.D., Brady S.F., Grossman T.H., Liles M.R., Loiacono K.A., Lynch B.A., MacNeil I.A., Minor C., Tiong C.L., Gilman M., Osburne M.S., Clardy J., Handelsman J., Goodman R.M. Appl. Environ. Microbiol. 66:2000;2541.
18. MacNeil I.A., Tiong C.L., Minor C., August P.R., Grossman T.H., Loiacono K.A., Lynch B.A., Phillips T., Narula S., Sundaramoorthi R., Tyler A., Aldredge T., Long H., Gilman M., Holt D., Osburne M.S. J. Mol. Microbiol. Biotechnol. 3:2001;301.
19. A. Quaiser, T. Ochsenreiter, H.-P. Klenk, A. Kletzin, A.H. Treusch, G. Meurer, J. Eck, C. Sensen, C. Schleper, Environ. Microbiol. (2002) in press.
20. Torsvik V., Goksoyr J. Soil Biol. Biochem. 10:1978;7.
21. Torsvik V. Soil Biol. Biochem. 12:1980;15.
22. J.T. Trevors, J.D. vanElsas, Nucleic Acids in the Environment - Methods and Applications, Springer, Berlin, Heidelberg, New York, 1995.
23. Krsek M., Wellington E.M. J. Microbiol. Meth. 39:1999;1.
24. Courtois S., Frostegard A., Goransson P., Depret G., Jeannin P., Simonet P. Environ. Microbiol. 3:2001;431.
25. Henne A., Schmitz R.A., Bomeke M., Gottschalk G., Daniel R. Appl. Environ. Microbiol. 66:2000;3113.
26. Torsvik V., Goksoyr J., Daae F.L. Appl. Environ. Microbiol. 56:1990;782.
27. Seed B., Parker R.C., Davidson N. Gene. 19:1982;201.
28. Johnson A.M., Dubey J.P., Dame J.B. Aust. J. Exp. Biol. Med. Sci. 64:1986;351.
29. Cottrell M.T., Moore J.A., Kirchman D.L. Appl. Environ. Microbiol. 65:1999;2553.
30. P. Lorenz, K. Liebeton, F. Niehaus, J. Eck, H. Zinke, in: Proceedings of the Fifth International Symposium on Biocatalysis and Biotransformation, 2-7 September 2001, Darmstadt, Germany, p. 379.
31. Gupta R., Beg Q.K., Lorenz P. Appl. Microbiol. Biotechnol. 59:2002;15.
32. Brady S.F., Chao C.J., Handelsman J., Clardy J. Org. Lett. 3:2001;1981.
33. K. Liebeton, P. Lorenz, F, Niehaus, T. Ochsenreiter, A. Qaiser, C. Schleper, J. Eck, H. Zinke, Conference Proceedings of the Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM) (2002), March 24-27 Göttingen, Germany, p. 88.