Genetic and environmental factors of atopy

Allergology International

Volumn 51, Issue 4, 2002, Pages 213-219

  Otsu, Akiko ^a   Shirakawa, Taro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Allergy; Asthma; Atopy; Fc RI ; Interleukin 13; Interleukin 4; Th1 Th2 imbalance

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4;

ALLERGIC DISEASE; ASTHMA; ATOPIC DERMATITIS; ATOPY; CLINICAL FEATURE; CYTOKINE PRODUCTION; DEVELOPED COUNTRY; ENVIRONMENTAL FACTOR; GENETIC VARIABILITY; HEREDITY; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOGLOBULIN PRODUCING CELL; PREVALENCE; PRIORITY JOURNAL; REVIEW; RHINOCONJUNCTIVITIS; RISK FACTOR; TH1 CELL; TH2 CELL;

EID: 0036970859     PISSN: 13238930     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1592.2002.00268.x     Document Type: Review

References (61)

1. Strannegård Ö, Strannegård IL. The causes of the increasing prevalence of allergy: Is atopy a microbial deprivation disorder? Allergy 2001; 56: 91-102.
2. Okudaira H, Shuto H, Shuto T et al. A shadow of Epstein-Barr virus in the pathogenesis of atopic diseases. Clin. Exp. Allergy 2001; 31: 18-24.
3. Shirakawa T, Enomoto T, Shimazu S, Hopkin JM. The inverse association between tuberculin responses and atopic disorder. Science 1997; 275: 77-9.
4. Shirakawa T, Morimoto K. Effect of lifestyle on levels of specific IgE antibodies. Allergy 1993; 48: 177-80.
5. Matricardi PM, Rosmini F, Ferrigno L et al. Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus. BMJ 1998; 314: 999-1003.
6. Perez OM, Morales W, Paniagua M, Strannegård Ö. Prevalence of antibodies to hepatitis A, B, C and E viruses in a healthy population in Leon, Nicaragua. Am. J. Trop. Med. Hygiene 1996; 55: 17-21.
7. Strachan DP. Family size, infection and atapy. The first decade of the hygiene hypothesis. Thorax 2000; 55: 2-10.
8. Shaheen SO, Aaby P, Hall AJ et al. Measles and atopy in Guinea-Bissau. Lancet 1996; 347: 1792-4.
9. Strannegård Ö, Strannegård IL. T lymphocyte numbers and function in human IgE-mediated allergy. Immunol. Rev. 1978; 41: 148-70.
10. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986; 136: 2348-57.
11. Benson M, Adner M, Cardell LO. Cytokines and cytokine receptors in allergic rhinitis: How do they relate to the Th2 hypothesis in allergy? Clin. Exp. Allergy 2001; 31: 361-7.
12. Shirakawa T, Deichmann KA, Izuhara K, Mao X-Q, Adra CN, Hopkin JM. Asthma, atopy and genetic variants of IL-4 and IL-13 signalling. Immunol. Today 2000; 21: 60-4.
13. Nelms K, Keegan AS, Zamorano J, Ryan JJ, Paul WE. The interleukin-4 receptor: Signal mechanisms and biologic functions. Annu. Rev. Immunol. 1999; 16: 701-36.
14. Yamaguchi Y, Suda T, Suda J et al. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 1988; 167: 1737-42.
15. Rivière I, Sunshine MJ, Littman DR. Regulation of IL-4 expression by activation of individual alleles. Immunity 1998; 9: 217-28.
16. Tang ML, Kemp AS, Thorburn J, Hill DJ. Reduced interferon-gamma secretion in neonates and subsequent atopy. Lancet 1994; 344: 983-5.
17. Warner JA, Miles EA, Jones AC, Quint DJ, Colwell BM, Warner J. Is deficiency of interferon gamma production by allergen-triggered cord blood cells a predictor of atopic eczema? Clin. Exp. Allergy 1994; 24: 423-30.
18. Martinez FD, Stern DA, Wright AL, Holberg CJ, Taussig LM, Halonen M. Association of interleukin-2 and interferon-gamma production by blood mononuclear cells in infancy with parental allergy skin tests and with subsequent development of atopy. J. Allergy Clin. Immunol. 1995; 96: 652-60.
19. Zuwarski G, de Vries JE. Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol. Today 1994; 15: 19-26.
20. Takeda K, Kishimoto T, Akira S. STAT6: Its role in interleukin 4-mediated biological functions. J. Mol. Med. 1997; 75: 317-26.
21. Deichmann K, Bardutzky J, Forster J, Heinzmann A, Kuehr J. Common polymorphisms in the coding part of the IL4-receptor gene. Biochem. Biophys. Res. Commun. 1997; 231: 696-7.
22. Idzerda RL, March CJ, Mosley B et al. Human interleukin 4 receptor confers biological responsiveness and defines a navel receptor superfamily. J. Exp. Med. 1990; 171: 861-73.
23. Galizzi JP, Zuber CE, Harada N et al. Molecular cloning of a cDNA encoding the human interleukin 4 receptar. Int. Immunol. 1990; 2: 669-75.
24. Mitsuyasu H, Izuhara K, Mao X-Q et al. Ile50Val variant of IL4R upregulates IgE synthesis and associates with atopic asthma. Nat. Genet. 1998; 19: 119-20.
25. Kruse S, Japha T, Tedner M et al. The polymorphisms S503P and Q576R in the interleukin-4 receptor gene are associated with atopy and influence signal transduction. Immunology 1999; 96: 365-71.
26. Mitsuyasu H, Yanagihara Y, Mao X-Q et al. Cutting edge. Dominant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis. J. Immunol. 1999; 162: 1227-31.
27. Izuhara K, Shirakawa T. Signal transduction via the interleukin-4 receptor and its correlation with atopy. Int. J. Mol. Med. 1999; 3: 3-10.
28. Heinzmann A, Mao X-Q, Akaiwa M et al. Genetic variants of IL-13 signalling and human asthma and atopy. Hum. Mol. Genet. 2000; 9: 549-59.
29. Bancroft AJ, McKenzie AN, Grencis RK. A critical role for IL-13 in resistance to intestinal nematode infection. J. Immunol. 1998; 160: 3453-61.
30. Grunig G, Warnock M, Wakil AE et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 282: 2261-3.
31. Wills-Karp M, Luyimbazi J, Xu X et al. Interleukin-13: Central mediator of allergic asthma. Science 1998; 282: 2258-61.
32. Humbert M, Durham SR, Kimmitt P et al. Elevated expression of messenger ribonucleic acid encading IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma. J. Allergy Clin. Immunol. 1997; 99: 657-65.
33. Huang SK, Xiao HQ, Kleine-Tebbe J et al. IL-13 expression at the sites of allergen challenge in patients with asthma. J. Immunol. 1995; 155: 2688-94.
34. Cookson WOCM, Sharp P, Faux JA, Hopkin JM. Linkage between immunoglobulin E responses underlying asthma and rhinitis chromosome 11q. Lancet 1989; i: 1292-5.
35. Cookson WOCM, Young RP, Sandford AJ et al. Maternal inheritance of atopic IgE responsiveness on chromosome 11q. Lancet 1992; 340: 381-4.
36. Sandford AJ, Shirakawa T, Moffatt MF et al. Localisation of atopy and subunit of high affinity IgE receptor (FcRI) on chromosome 11q. Lancet 1993; 341: 332-4.
37. Young RP, Sharp P, Lynch J et al. Confirmation of genetic linkage between atopic IgE responses and chromosome 11q13. J. Med. Genet. 1992; 29: 236-8.
38. Moffatt MF, Sharp PA, Faux JA, Young RP, Cookson WOCM, Hopkin JM. Factors confounding genetic linkage between atopy and chromosome 11q. Clin. Exp. Allergy 1992; 22: 1046-51.
39. Szepetowski P, Gaudray P. FCERIB, a candidate gene for atopy, is located in 11q13 between CD20 and TCN1. Genomics 1994; 19: 399-400.
40. Stafford AN, Rider SH, Hopkin JM, Cookson WOCM, Monaco AP. A 28 Mb YAC contig in 11q12-q13 localizes candidate genes for atopy: FcRI CD20. Hum. Mol. Genet. 1994; 3: 779-85.
41. Sandford AJ, Moffatt MF, Daniels DE et al. A genetic map of chromosome 11q, including the atopy lacus. Eur. J. Hum. Genet. 1995; 3: 188-94.
42. Adra CN, Mao X-Q, Kawada H et al. Chromosome 11q13 and atopic asthma. Clin. Genet. 1999; 55: 431-7.
43. Van Herwerden L, Harrap SB, Wong ZYH et al. Linkage of high-affinity IgE receptor gene with bronchial hyperreactivity, even in absence of atopy. Lancet 1995; 346: 1262-5.
44. Kuster H, Zhang L, Brini AT, MacGlashan DWJ, Kinet J-P. The gene and cDNA for the human high affinity IgE receptor beta chain and expression of the complete receptor. J. Biol. Chem. 1992; 267: 12 782-7.
45. Shirakawa T, Li A, Dubowitz M et al. Association between atopy and variants of the subunit of high affinity immunoglobulin E receptor. Nat. Genet. 1994; 7: 125-30.
46. Li A, Hopkin JM. Atopy phenotype in subjects with variants of the subunit of the high affinity IgE receptor. Thorax 1997; 52: 654-5.
47. Hill MR, James AL, Faux JA et al. FcRI polymorphism and risk of atopy in a general population. BMJ 1995; 311: 776-9.
48. Hill MR, Cookson WOCM. A novel coding polymorphism of the C-terminal in FcRI is associated with atopy and bronchial hyper-responsiveness. Hum. Mol. Genet. 1996; 5: 959-62.
49. Shirakawa T, Mao X-Q, Sasaki S et al. Association between atopic asthma and a coding variant of FcRI in a Japanese population. Hum. Mol. Genet. 1996; 5: 1129-30.
50. Adra CN, Mao X-Q, Yamasaki A et al. Chromosome 11q13, FcRI and atopic asthma. In: Holgate S, Holloway J (eds). The Hereditary Basis of Allergic Diseases. Basel: Birkhauser Verlag. 2002 (in press).
51. Hijazi Z, Haider MZ, Khan MR, Al-Dowaisan AA. High frequency of IgE receptor FcRI variant (Leu181/Leu183) in Kuwaiti Arabs and its association with asthma. Clin. Genet. 1998; 53: 149-50.
52. Green SL, Gaillard MC, Song E, Dewar JB, Halkas A. Polymorphisms of the β chain of the high-affinity immunogloblin E rceptor (FcRI) in South African black and white asthmatic and nonasthmatic individuals. Am. J. Respir. Crit. Care Med. 1998; 158: 1487-92.
53. Shirakawa T, Mao X-Q, Sasaki S, Kawai M, Morimota K, Hopkin JM. Association between FcRI and atopic disorders in a Japanese population. Lancet 1996; 347: 349-50.
54. Palmer LJ, Pare PD, Faux JA et al. FcRI-palymorphism and total serum IgE levels in endemically parasitized Australian Aborigines. Am. J. Hum. Genet. 1997; 61: 182-8.
55. Cox HE, Moffatt MF, Faux JA et al. Association of atopic dermatitis to the beta subunit of the high affinity immunoglobulin E receptor. Br. J. Dermatol. 1998; 138: 182-7.
56. Tanaka K, Sugiura H, Uehara M, Sato H, Hashimoto-Tamaoki T, Furuyama J. Association between mast cell chymase genotype and atopic eczema: Comparison between patients with atopic eczema alone and those with atapic eczema and atopic respiratory disease. Clin. Exp. Allergy 1999; 29: 800-3.
57. Laing IA, Goldblatt J, Eber E et al. A polymorphism of the CC16 gene is associated with an increased risk of asthma. J. Med. Genet. 1998; 35: 463-7.
58. Chapman CG, Browne J. Isolation of the human ml (Hml) muscarinic acetylcholine receptor gene by PCR amplification. Nucleic Acids Res. 1990; 18: 2191.
59. Neely JD, Buffy DL, Breazeale DR et al. Linkage analysis of IgE and chromosome 11q13. Am. J. Respir. Crit. Care Med. 1996; 153: A767 (Abstract).
60. Doull IJM, Lawrence S, Watson M et al. Allelic association of gene markers on chromosome 5q and 11q with atopy and bronchial hyperresponsiveness. Am. J. Respir. Crit. Care Med. 1996; 153: 1280-4.
61. Hizawa N, Yamaguchi E, Furuya K et al. Association between high serum total IgE levels and D11S97 on chromosome 11q13 in Japanese subjects. J. Med. Genet. 1995; 32: 363-9.