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Volumn 21, Issue 2, 2000, Pages 60-64

Atopy and asthma: Genetic variants of IL-4 and IL-13 signalling

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR;

EID: 0034142166     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(99)01492-9     Document Type: Short Survey
Times cited : (265)

References (31)
  • 1
    • 0032622175 scopus 로고    scopus 로고
    • Signal transduction via the interleukin-4 receptor and its correlation with atopy
    • Izuhara K., Shirakawa T. Signal transduction via the interleukin-4 receptor and its correlation with atopy. Int. J. Mol. Med. 3:1999;3-10.
    • (1999) Int. J. Mol. Med. , vol.3 , pp. 3-10
    • Izuhara, K.1    Shirakawa, T.2
  • 2
    • 0032545213 scopus 로고    scopus 로고
    • Interleukin-13: Central mediator of allergic asthma
    • Wills-Karp M.et al. Interleukin-13: central mediator of allergic asthma. Science. 282:1998;2258-2261.
    • (1998) Science , vol.282 , pp. 2258-2261
    • Wills-Karp, M.1
  • 3
    • 0032545433 scopus 로고    scopus 로고
    • Requirement for IL-13 independently of IL-4 in experimental asthma
    • Grunig G.et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science. 282:1998;2261-2263.
    • (1998) Science , vol.282 , pp. 2261-2263
    • Grunig, G.1
  • 4
    • 0028230946 scopus 로고
    • Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
    • Marsh M.G.et al. Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science. 264:1994;1152-1156.
    • (1994) Science , vol.264 , pp. 1152-1156
    • Marsh, M.G.1
  • 5
    • 0030903861 scopus 로고    scopus 로고
    • A genome-wide search for asthma susceptibility loci in ethnically diverse populations
    • A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat. Genet. 15:1997;389-392.
    • (1997) Nat. Genet. , vol.15 , pp. 389-392
  • 6
    • 7344248546 scopus 로고    scopus 로고
    • Genome-wide search for asthma susceptibility loci in a founder population
    • Ober C.et al. Genome-wide search for asthma susceptibility loci in a founder population. Hum. Mol. Genet. 9:1998;1393-1398.
    • (1998) Hum. Mol. Genet. , vol.9 , pp. 1393-1398
    • Ober, C.1
  • 7
    • 0031931549 scopus 로고    scopus 로고
    • Linkage and allelic association of atopy and markers flanking the IL-4-receptor gene
    • Deichmann K.A.et al. Linkage and allelic association of atopy and markers flanking the IL-4-receptor gene. Clin. Exp. Allergy. 28:1997;151-155.
    • (1997) Clin. Exp. Allergy , vol.28 , pp. 151-155
    • Deichmann, K.A.1
  • 8
    • 0030656507 scopus 로고    scopus 로고
    • Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population
    • Noguchi E.et al. Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population. Am. J. Respir. Crit. Care Med. 156:1997;1390-1393.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 1390-1393
    • Noguchi, E.1
  • 9
    • 0033027212 scopus 로고    scopus 로고
    • Analysis of two IL-4 promoter polymorphisms in a cohort of atopic and asthmatic subjects
    • Hook S.et al. Analysis of two IL-4 promoter polymorphisms in a cohort of atopic and asthmatic subjects. Exp. Clin. Immunogenet. 16:1997;33-35.
    • (1997) Exp. Clin. Immunogenet. , vol.16 , pp. 33-35
    • Hook, S.1
  • 10
    • 0032988804 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-4 receptor polymorphisms in minimal change nephropathy
    • Parry R.G.et al. Interleukin-4 and interleukin-4 receptor polymorphisms in minimal change nephropathy. Clin. Sci. 96:1999;665-668.
    • (1999) Clin. Sci. , vol.96 , pp. 665-668
    • Parry, R.G.1
  • 11
    • 0030801870 scopus 로고    scopus 로고
    • Genetics of atopy and asthma: The rationale behind promoter-based candidate gene studies (IL-4 and IL-10)
    • Rosenwasser L.J., Borish L. Genetics of atopy and asthma: the rationale behind promoter-based candidate gene studies (IL-4 and IL-10). Am. J. Respir. Crit. Care Med. 156:1997;S152-S155.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156
    • Rosenwasser, L.J.1    Borish, L.2
  • 12
    • 0032510452 scopus 로고    scopus 로고
    • A distinct role for interleukin-13 in Th2-cell-mediated immune responses
    • McKenzie G.J.et al. A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Curr. Biol. 8:1998;339-342.
    • (1998) Curr. Biol. , vol.8 , pp. 339-342
    • McKenzie, G.J.1
  • 13
    • 0033188305 scopus 로고    scopus 로고
    • An IL-13 promoter polymorphism associated with increased risk of allergic asthma
    • van der Pouw Kraan T.C.T.M.et al. An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes Immunity. 1:1999;61-65.
    • (1999) Genes Immunity , vol.1 , pp. 61-65
    • Van der Pouw Kraan, T.C.T.M.1
  • 14
    • 0034162827 scopus 로고    scopus 로고
    • Genetic variants of IL-13 signalling and human asthma and atopy
    • (in press)
    • Heinzmann A.et al. Genetic variants of IL-13 signalling and human asthma and atopy. Hum. Mol. Genet. 2000;. (in press).
    • (2000) Hum. Mol. Genet.
    • Heinzmann, A.1
  • 15
    • 0001325237 scopus 로고    scopus 로고
    • The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor
    • Hershey, K.G.H. et al. (1997) The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. New Engl. J. Med. 1720-1725.
    • (1997) New Engl. J. Med. , pp. 1720-1725
    • Hershey, K.G.H.1
  • 16
    • 0032499069 scopus 로고    scopus 로고
    • The interleukin-4 receptor variant Q576R in hyper-IgE syndrome
    • Glimbacher B.et al. The interleukin-4 receptor variant Q576R in hyper-IgE syndrome. New Engl. J. Med. 338:1998;1073-1074.
    • (1998) New Engl. J. Med. , vol.338 , pp. 1073-1074
    • Glimbacher, B.1
  • 17
    • 0033561683 scopus 로고    scopus 로고
    • Effects of an allergy-associated mutation in the human IL-4R α(Q576R) on human IL-4-induced signal transduction
    • Wang H.Y.et al. Effects of an allergy-associated mutation in the human IL-4R α(Q576R) on human IL-4-induced signal transduction. J. Immunol. 162:1999;4385-4389.
    • (1999) J. Immunol. , vol.162 , pp. 4385-4389
    • Wang, H.Y.1
  • 18
    • 0032981094 scopus 로고    scopus 로고
    • The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction
    • Kruse S.et al. The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction. Immunology. 96:1999;365-371.
    • (1999) Immunology , vol.96 , pp. 365-371
    • Kruse, S.1
  • 19
    • 0033083286 scopus 로고    scopus 로고
    • Dominant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis
    • Mitsuyasu H.et al. Dominant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis. J. Immunol. 162:1999;1227-1231.
    • (1999) J. Immunol. , vol.162 , pp. 1227-1231
    • Mitsuyasu, H.1
  • 20
    • 18844480971 scopus 로고    scopus 로고
    • Ile50Val variant of IL-4Rα upregulates IgE synthesis and associates with atopic asthma
    • Mitsuyasu H.et al. Ile50Val variant of IL-4Rα upregulates IgE synthesis and associates with atopic asthma. Nat. Genet. 19:1998;119-120.
    • (1998) Nat. Genet. , vol.19 , pp. 119-120
    • Mitsuyasu, H.1
  • 21
    • 0030670147 scopus 로고    scopus 로고
    • Molecular characterization and functional analysis of murine interleukin 4 receptor allotypes
    • Schulte T.et al. Molecular characterization and functional analysis of murine interleukin 4 receptor allotypes. J. Exp. Med. 186:1997;1419-1429.
    • (1997) J. Exp. Med. , vol.186 , pp. 1419-1429
    • Schulte, T.1
  • 22
    • 0032167603 scopus 로고    scopus 로고
    • The murine IL-13 receptor α2: Molecular cloning, characterization, and comparison with murine IL-13 receptor α1
    • Donaldson D.D.et al. The murine IL-13 receptor α2: molecular cloning, characterization, and comparison with murine IL-13 receptor α1. J. Immunol. 161:1998;2317-2324.
    • (1998) J. Immunol. , vol.161 , pp. 2317-2324
    • Donaldson, D.D.1
  • 23
    • 0032169072 scopus 로고    scopus 로고
    • Localization of the human stat6 gene to chromosome 12q13.3-q14.1, a region implicated in multiple solid tumors
    • Patel B.K.R.et al. Localization of the human stat6 gene to chromosome 12q13.3-q14.1, a region implicated in multiple solid tumors. Genomics. 52:1998;192-200.
    • (1998) Genomics , vol.52 , pp. 192-200
    • Patel, B.K.R.1
  • 24
    • 0008886299 scopus 로고    scopus 로고
    • Stat6 in atopic asthma
    • (in press)
    • Gao P-S.et al. Stat6 in atopic asthma. J. Med. Genet. 2000;. (in press).
    • (2000) J. Med. Genet.
    • Gao, P-S.1
  • 25
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal center formation and Th-2 type inflammation
    • Ye B.H.et al. The BCL-6 proto-oncogene controls germinal center formation and Th-2 type inflammation. Nat. Genet. 16:1997;161-170.
    • (1997) Nat. Genet. , vol.16 , pp. 161-170
    • Ye, B.H.1
  • 26
    • 0031756460 scopus 로고    scopus 로고
    • Variants of B cell lymphoma 6 (BCL6) and marked atopy
    • Adra C.N.et al. Variants of B cell lymphoma 6 (BCL6) and marked atopy. Clin. Genet. 54:1998;362-364.
    • (1998) Clin. Genet. , vol.54 , pp. 362-364
    • Adra, C.N.1
  • 27
    • 0032133157 scopus 로고    scopus 로고
    • A conditionally active form of STAT6 can mimic certain effects of IL-4
    • Kamogawa Y.et al. A conditionally active form of STAT6 can mimic certain effects of IL-4. J. Immunol. 161:1998;1074-1077.
    • (1998) J. Immunol. , vol.161 , pp. 1074-1077
    • Kamogawa, Y.1
  • 28
    • 0031803359 scopus 로고    scopus 로고
    • Sensitization of human airways: What is the role of immunoglobulin-E?
    • Tunon de Lara J.M. Sensitization of human airways: what is the role of immunoglobulin-E? Clin. Exp. Allergy. 28:1998;660-663.
    • (1998) Clin. Exp. Allergy , vol.28 , pp. 660-663
    • Tunon de Lara, J.M.1
  • 29
    • 0032725001 scopus 로고    scopus 로고
    • The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: More similarities than differences
    • Humbert M.et al. The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences. Immunol. Today. 20:1999;528-533.
    • (1999) Immunol. Today , vol.20 , pp. 528-533
    • Humbert, M.1
  • 30
    • 0031584822 scopus 로고    scopus 로고
    • Common polymorphisms in the coding part of the IL4-receptor gene
    • Deichmann K.A.et al. Common polymorphisms in the coding part of the IL4-receptor gene. Biochem. Biophy. Res. Commun. 231:1997;696-697.
    • (1997) Biochem. Biophy. Res. Commun. , vol.231 , pp. 696-697
    • Deichmann, K.A.1
  • 31
    • 0032009864 scopus 로고    scopus 로고
    • Structure of and signal transduction through interleukin-4 and interleukin-13 receptors
    • Murata T.et al. Structure of and signal transduction through interleukin-4 and interleukin-13 receptors. Int. J. Mol. Med. 1:1998;551-557.
    • (1998) Int. J. Mol. Med. , vol.1 , pp. 551-557
    • Murata, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.