Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness

American Journal of Respiratory and Critical Care Medicine

Volumn 153, Issue 4 PART I, 1996, Pages 1280-

  Doull, Iolo J M ^a   Lawrence, Sharon ^b   Watson, Mark ^b   Begishvili, Toresh ^b   Beasley, Richard W ^b   Lampe, Fiona ^b   Holgate, Stephen T ^b   Morton, Newton E ^b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ALLELE; ARTICLE; ATOPY; BRONCHUS HYPERREACTIVITY; CHILD; CHROMOSOME 11Q; CHROMOSOME 5Q; FEMALE; GENE CLUSTER; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ALLELES; ASTHMA; BRONCHIAL HYPERREACTIVITY; CHILD; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 5; ECZEMA; GENETIC MARKERS; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-9; LINKAGE (GENETICS); MIDDLE AGED; RHINITIS, ALLERGIC, SEASONAL;

EID: 0029968806     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.153.4.8616554     Document Type: Article

References (16)

1. Morton, N. E. 1992. Major loci for atopy? 1992. Clin. Exp. Allergy 22:1041-1043.
2. Cookson, W. O. C. M., R. P. Young, A. J. Sandford, M. F. Moffat, T. Shirakawa, P. A. Sharp, J. A. Faux, C. Julier, P. N. Le Souef, Y. Nakamura, G. M. Lathrop, and J. M. Hopkin. 1992. Maternal inheritance of maternal IgE responsiveness on chromosome 11q. Lancet 340:381-384.
3. Sears, M., B. Burrows, E. M. Flannery, G. P. Herbison, C. J. Hewitt, and M. D. Holdaway. 1991. Relation between airway responsiveness and serum IgE in children with asthma and apparently normal children. N. Engl. J. Med. 325:1067-1071.
4. Romagnani, S. 1991. Human TH1 and TH2: doubt no more. Immunol. Today 12:256-257.
5. Marsh, D. G., J. D. Neely, D. R. Breazeale, B. Ghosh, L. R. Freidhoff, E. Ehrlich-Kautzy, C. Schou, G. Krishnaswamy, and T. H. Beaty. 1994. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum Immunoglobulin E concentrations. Science 264:1152-1156.
6. Meyers, D. A., D. S. Postma, C. I. M. Panhuysen, P. J. Amelung, R. C. Levitt, and E. R. Bleeker. 1994. Evidence for a locus regulating serum IgE levels mapping to chromosome 5. Genomics 23:464-470.
7. Cookson, W. O. C. M., P. A. Sharp, J. A. Faux, and J. M. Hopkin. 1989. Linkage between immunoglobulin E responses underlying asthma and rhinitis on chromosome 11q. Lancet 1:1292-1294.
8. Shirakawa, T., A. Li, M. Dubowitz, J. W. Dekker, A. E. Shaw, J. A. Faux, C. Ra, W. O. C. M. Cookson, and J. M. Hopkin. 1994. Association between atopy and variants of the β subunit of the high affinity immunoglobulin E receptor. Nature Genet. 7:125-130.
9. Collee, J. M., L. P. ten Kate, H. G. de Vries, J. W. Kliphuis, and H. Scheffer. 1993. Allele sharing on chromosome 11q13 in sibs with asthma and atopy. Lancet 342:936.
10. Shirakawa, T., T. Hashimoto, J. Furuyama, and K. Morimoto. 1994. Linkage between severe atopy and chromosome 11q13 in Japanese families. Clin. Genet. 46:228-232.
11. Amelung, P. J., C. I. M. Panhuysen, D. S. Postma, R. C. Levitt, G. H. Koeter, C. A. Francomano, E. R. Bleeker, and D. A. Meyers. 1992. Atopy, asthma and bronchial hyperresponsiveness: Exclusion of linkage to markers on chromosome 11q and 6p. Clin. Exp. Allergy 22: 1077-1084.
12. Rich, S. S., B. Roitman-Johnson, B. Greenburg, S. Roberts, and M. N. Blumenthal. 1992. Genetic analysis of atopy in three large kindreds: no evidence of linkage to D11S97. Clin. Exp. Allergy 22:1070-1076.
13. Lympany, P., K. I. Welsh, G. M. Cochrane, D. M. Kemeny, and T. H. Lee. 1992. Genetic analysis of the linkage between chromosome 11q and atopy. Clin. Exp. Allergy 22:1085-1092.
14. Hizawa, N., E. Yamaguchi, M. Ohe, A. Itoh, K. Furuya, N. Ohnuma, and Y. Kawakami. 1992. Lack of linkage between atopy and locus 11q13. Clin. Exp. Allergy 22:1065-1069.
15. Coleman, R., R. C. Trembath, and J. I. Harper. 1993. Chromosome 11q13 and atopy underlying atopic eczema. Lancet 341:1121-1122.
16. Watson, M., S. Lawrence, A. Collins, R. Beasley, I. Doull, B. Begishvili, F. Lampe, S. T. Holgate, and N. E. Morton. 1995. Exclusion from proximal 11q of a common gene with megaphenic effect on atopy. Ann. Hum. Genet. 59:403-411.