High frequency of IgE receptor FcεRIβ variant (Leu181/Leu183) in Kuwaiti Arabs and its association with asthma

Clinical Genetics

Volumn 53, Issue 2, 1998, Pages 149-152

  Hijazi, Z ^a   Haider, M Z ^a   Khan, M R ^b   Al Dowaisan, A A ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b AL SABAH HOSPITAL   (Kuwait)

Author keywords

Asthma; IgE; PCR; Receptor polymorphism

Indexed keywords

IMMUNOGLOBULIN E RECEPTOR;

ARAB; ARTICLE; ASTHMA; CONTROLLED STUDY; ECZEMA; GENETIC SCREENING; GENOTYPE; HAY FEVER; HOMOZYGOTE; HUMAN; KUWAIT; MAJOR CLINICAL STUDY; PRICK TEST; PRIORITY JOURNAL;

EID: 0031958519     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0004.1998.tb02664.x     Document Type: Article

References (13)

1. Stenius B, Wide L, Seymour WM, Holford-Strevens V, Pepys J. Clinical significance of specific IgE to common allergens. I. Relationship of specific IgE against Dermatophagoides spp. and grass pollen to skin and nasal tests and history. Clin Allergy 1971: 1: 37-55.
2. Ravetch J, Kinet J-P. Fc receptors. Ann Rev Immunol 1991: 9: 457-492.
3. Cookson WOCM, Sharp PA, Faux JA, Hopkin JM. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet 1989: 333: 1292-1295.
4. Cookson WOCM, Young RP, Sandford AJ, Moffatt MF, Shrikawa T, Sharp PA, et al. Maternal inheritance of atopic IgE responsiveness on chromosome 11q. Lancet 1992: 340: 381-384.
5. Marsh DG, Meyers DA. A major gene for allergy-fact or fantacy? Nat Genet 1992: 2: 252-254.
6. Shirakawa T, Li A, Dubowitz M, Dekker JW, Shaw A, Ra C, Cookson WOCM, Hopkin JM. Association between atopy and variants of the β subunit of the high affinity immunoglobulin E receptor. Nat Genet 1994: 7: 125-130.
7. Dombrowicz D, Flamand V, Brigman KK, Koller BH, Kinet J-P. Abolition of anaphylaxis by targetted disruption of the high affinity immunoglobulin receptor α chain gene. Cell 1993: 75: 969-976.
8. Paul WE, Seder RA, Plant M. Lymphokine and cytokine production by FcεRI+ cells. Adv Immunol 1992: 53: 1-29.
9. Sambrook J, Maniatis T, Fritish J. Molecular Cloning: A Laboratory Manual, 2nd. edn. New York: Cold Spring Harbor Laboratory, 1989.
10. Hill MR, James AL, Faux JA, Ryan G, Hopkin JM, le Souef P, Musk AW, Cookson WOCM. FcεRIβ polymorphism and risk of atopy in a general population sample. Br Med J 1995: 311: 776-779.
11. Kofler H, Aichberger S, Ott G, Casari A, Kofler R. Lack of association between atopy and the Ile181Leu variant of the beta subunit of high affinity immunoglobulin E receptor. Int Arch Allergy Immunol 1996: 111: 44-47.
12. Varin-Blank N, Metzger H. Surface expression of mutated subunits of the high affinity mast cell receptor for IgE. J Biol Chem 1990: 265: 15685-15694.
13. Beinborn M, Lee Y-M, McBride EW, Quinn SM, Kopin AS. A single amino acid of the cholicystokinin-B/gastrin receptor determines specificity for non-peptide anatgonists. Nature 1993: 362: 348-350.