-
1
-
-
0027516927
-
Therapy of the newly diagnosed adult with acute lymphoblastic leukemia
-
Hoelzer DF. Therapy of the newly diagnosed adult with acute lymphoblastic leukemia. Hematology and Oncology Clinics of North America 7: 1993; 139-160.
-
(1993)
Hematology and Oncology Clinics of North America
, vol.7
, pp. 139-160
-
-
Hoelzer, D.F.1
-
2
-
-
0028938844
-
A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: Cancer and Leukemia Group B study 8811
-
Larson RA, Dodge RK, Burns CP et al. A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: Cancer and Leukemia Group B study 8811. Blood 1995; 85: 2025-2037.
-
(1995)
Blood
, vol.85
, pp. 2025-2037
-
-
Larson, R.A.1
Dodge, R.K.2
Burns, C.P.3
-
3
-
-
0033964380
-
Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia
-
Kantarjian HM, O'Brien S, Smith TL et al. Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. Journal of Clinical Oncology 2000; 18: 547-561.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 547-561
-
-
Kantarjian, H.M.1
O'Brien, S.2
Smith, T.L.3
-
4
-
-
13344285351
-
Improved outcome in adult B-cell acute lymphoblastic leukemia
-
Hoelzer D, Ludwig WD, Thiel E et al. Improved outcome in adult B-cell acute lymphoblastic leukemia. Blood 1996; 87: 495-508.
-
(1996)
Blood
, vol.87
, pp. 495-508
-
-
Hoelzer, D.1
Ludwig, W.D.2
Thiel, E.3
-
5
-
-
0032812621
-
Hyper-CVAD program in Burkitt's-type adult acute lymphoblastic leukemia
-
Thomas DA, Cortes J, O'Brien S et al. Hyper-CVAD program in Burkitt's-type adult acute lymphoblastic leukemia. Journal of Clinical Oncology 1999: 17: 2461-2470.
-
(1999)
Journal of Clinical Oncology
, vol.17
, pp. 2461-2470
-
-
Thomas, D.A.1
Cortes, J.2
O'Brien, S.3
-
6
-
-
0033954540
-
Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia
-
Faderl S, Kantarjian HM, Thomas DA et al. Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. Leukemia and Lymphoma 2000; 36: 263-273.
-
(2000)
Leukemia and Lymphoma
, vol.36
, pp. 263-273
-
-
Faderl, S.1
Kantarjian, H.M.2
Thomas, D.A.3
-
7
-
-
0034765167
-
Drug resistance in hematologic malignancies
-
Marie JP. Drug resistance in hematologic malignancies. Current Opinion in Oncology 2001; 13: 463-469.
-
(2001)
Current Opinion in Oncology
, vol.13
, pp. 463-469
-
-
Marie, J.P.1
-
8
-
-
0036192430
-
In vitro drug resistance profiles of adult acute lymphoblastic leukemia: Possible explanation for difference in outcome to similar therapeutic regimens
-
Styczynski J & Wysocki M. In vitro drug resistance profiles of adult acute lymphoblastic leukemia: possible explanation for difference in outcome to similar therapeutic regimens. Leukemia and Lymphoma 2002; 43: 301-307.
-
(2002)
Leukemia and Lymphoma
, vol.43
, pp. 301-307
-
-
Styczynski, J.1
Wysocki, M.2
-
9
-
-
0031681258
-
Anti-asparaginase antibodies following E coli asparaginase therapy in pediatric acute lymphoblastic leukemia
-
Woo MH, Hak LJ, Storm MC et al. Anti-asparaginase antibodies following E coli asparaginase therapy in pediatric acute lymphoblastic leukemia. Leukemia 1998; 12: 1527-1533.
-
(1998)
Leukemia
, vol.12
, pp. 1527-1533
-
-
Woo, M.H.1
Hak, L.J.2
Storm, M.C.3
-
10
-
-
0036255941
-
Antibody formation during intravenous and intramuscular therapy with Erwinia asparaginase
-
Albertsen BK, Schroder H, Jakobsen P et al. Antibody formation during intravenous and intramuscular therapy with Erwinia asparaginase. Medical and Pediatric Oncology 2002; 38: 310-316.
-
(2002)
Medical and Pediatric Oncology
, vol.38
, pp. 310-316
-
-
Albertsen, B.K.1
Schroder, H.2
Jakobsen, P.3
-
11
-
-
0027536607
-
L-asparaginase and PEG asparaginase - Past, present, and future
-
Keating MJ, Holmes R, Lerner S & Ho DH. L-asparaginase and PEG asparaginase - past, present, and future. Leukemia and Lymphoma 1993; 10: 153-157.
-
(1993)
Leukemia and Lymphoma
, vol.10
, pp. 153-157
-
-
Keating, M.J.1
Holmes, R.2
Lerner, S.3
Ho, D.H.4
-
12
-
-
0032613231
-
The three asparaginases Comparative pharmacology and optimal use in childhood leukemia
-
Asselin BL. The three asparaginases Comparative pharmacology and optimal use in childhood leukemia. Advances in Experimental Medicine and Biology 1999; 457: 621-629.
-
(1999)
Advances in Experimental Medicine and Biology
, vol.457
, pp. 621-629
-
-
Asselin, B.L.1
-
13
-
-
0034284267
-
Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: A Pediatric Oncology Group Study
-
Abshire TC, Pollock BH, Billett AL et al. Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: a Pediatric Oncology Group Study. Blood 2000; 96: 1709-1715.
-
(2000)
Blood
, vol.96
, pp. 1709-1715
-
-
Abshire, T.C.1
Pollock, B.H.2
Billett, A.L.3
-
14
-
-
0037089437
-
Comparison of Escherichia coli asparaginase with Erwinia asparaginase in the treatment of childhood lymphoid malignancies: Results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial
-
Duval M, Suciu S, Ferster A et al. Comparison of Escherichia coli asparaginase with Erwinia asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial. Blood 2002; 99: 2734-2739.
-
(2002)
Blood
, vol.99
, pp. 2734-2739
-
-
Duval, M.1
Suciu, S.2
Ferster, A.3
-
15
-
-
0028085149
-
Nation-wide randomized comparative study of doxorubicin, vincristine and prednisolone combination therapy with and without L-asparaginase for adult acute lymphoblastic leukemia
-
Nagura E, Kimura K, Yamada K et al. Nation-wide randomized comparative study of doxorubicin, vincristine and prednisolone combination therapy with and without L-asparaginase for adult acute lymphoblastic leukemia. Cancer Chemotherapy and Pharmacology 1994; 33: 359-365.
-
(1994)
Cancer Chemotherapy and Pharmacology
, vol.33
, pp. 359-365
-
-
Nagura, E.1
Kimura, K.2
Yamada, K.3
-
16
-
-
0037085747
-
A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: A Children's Cancer Group study
-
Avramis VI, Sencer S, Periclou AP et al. A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study. Blood 2002; 99: 1986-1994.
-
(2002)
Blood
, vol.99
, pp. 1986-1994
-
-
Avramis, V.I.1
Sencer, S.2
Periclou, A.P.3
-
17
-
-
0033214796
-
Combination therapy with methotrexate, vincristine, polyethylene-glycol conjugated-asparaginase, and prednisone in the treatment of patients with refractory or recurrent acute lymphoblastic leukemia
-
Aguayo A, Cortes J, Thomas D et al. Combination therapy with methotrexate, vincristine, polyethylene-glycol conjugated-asparaginase, and prednisone in the treatment of patients with refractory or recurrent acute lymphoblastic leukemia. Cancer 1999; 86: 1203-1209.
-
(1999)
Cancer
, vol.86
, pp. 1203-1209
-
-
Aguayo, A.1
Cortes, J.2
Thomas, D.3
-
18
-
-
0036163591
-
PEG-asparaginase (Oncaspar) 2500 U/m(2) BSA in reinduction and relapse treatment in the ALL/NHL-BFM protocols
-
Muller HJ, Beier R, da Palma JC et al. PEG-asparaginase (Oncaspar) 2500 U/m(2) BSA in reinduction and relapse treatment in the ALL/NHL-BFM protocols. Cancer Chemotherapy and Pharmacology 2002; 49: 149-154.
-
(2002)
Cancer Chemotherapy and Pharmacology
, vol.49
, pp. 149-154
-
-
Muller, H.J.1
Beier, R.2
da Palma, J.C.3
-
19
-
-
0034893950
-
Liposomal and nonliposomal drug pharmacokinetics after administration of liposome-encapsulated vincristine and their contribution to drug tissue distribution properties
-
Krishna R, Webb MS, St Onge G & Mayer LD. Liposomal and nonliposomal drug pharmacokinetics after administration of liposome-encapsulated vincristine and their contribution to drug tissue distribution properties. Journal of Pharmacology and Experimental Therapeutics 2001; 298: 1206-1212.
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.298
, pp. 1206-1212
-
-
Krishna, R.1
Webb, M.S.2
St Onge, G.3
Mayer, L.D.4
-
20
-
-
0033973456
-
Liposomal vincristine in relapsed non-Hodgkin's lymphomas: Early results of an ongoing phase II trial
-
Sarris AH, Hagemeister F, Romaguera J et al. Liposomal vincristine in relapsed non-Hodgkin's lymphomas: early results of an ongoing phase II trial. Annals of Oncology 2000; 11: 69-72.
-
(2000)
Annals of Oncology
, vol.11
, pp. 69-72
-
-
Sarris, A.H.1
Hagemeister, F.2
Romaguera, J.3
-
21
-
-
0003325207
-
Phase II study of liposomal vincristine (LipoV) in relapsed or refractory adult acute lymphoblastic leukemia (ALL)
-
abstract 4269
-
Thomas DA, Sarris A, O'Brien S et al. Phase II study of liposomal vincristine (LipoV) in relapsed or refractory adult acute lymphoblastic leukemia (ALL). Blood 1999; 94: 238b. abstract 4269.
-
(1999)
Blood
, vol.94
-
-
Thomas, D.A.1
Sarris, A.2
O'Brien, S.3
-
22
-
-
0032845069
-
Phase I study of liposomal daunorubicin in patients with acute leukemia
-
Cortes J, O'Brien S, Estey E et al. Phase I study of liposomal daunorubicin in patients with acute leukemia. Investigational New Drugs 1999; 17: 81-87.
-
(1999)
Investigational New Drugs
, vol.17
, pp. 81-87
-
-
Cortes, J.1
O'Brien, S.2
Estey, E.3
-
23
-
-
0035396908
-
High-dose liposomal daunorubicin and high-dose cytarabine combination in patients with refractory or relapsed acute myelogenous leukemia
-
Cortes J, Estey E, O'Brien S et al. High-dose liposomal daunorubicin and high-dose cytarabine combination in patients with refractory or relapsed acute myelogenous leukemia. Cancer 2001; 92: 7-14.
-
(2001)
Cancer
, vol.92
, pp. 7-14
-
-
Cortes, J.1
Estey, E.2
O'Brien, S.3
-
24
-
-
0003338248
-
A pilot study of dose-intensive anthracyclines for acute lymphoblastic leukemia (ALL) using liposomal daunorubicin (LD) with hyperfractionated cyclophosphamide (CTX), vincristine (VCR), and prednisone (PDN) (Hyper-CVXD)
-
abstract 110
-
Koller C, Cortes J, O'Brien S et al. A pilot study of dose-intensive anthracyclines for acute lymphoblastic leukemia (ALL) using liposomal daunorubicin (LD) with hyperfractionated cyclophosphamide (CTX), vincristine (VCR), and prednisone (PDN) (Hyper-CVXD). Proceedings of the American Society of Clinical Oncology 1998; 17: 28a. abstract 110.
-
(1998)
Proceedings of the American Society of Clinical Oncology
, vol.17
-
-
Koller, C.1
Cortes, J.2
O'Brien, S.3
-
25
-
-
0028269761
-
Relationship between daunorubicin dosage delivered during induction therapy and outcome in adult acute lymphoblastic leukemia
-
Todeschini G, Meneghini V, Pizzolo G et al. Relationship between daunorubicin dosage delivered during induction therapy and outcome in adult acute lymphoblastic leukemia. Leukemia 1994; 8: 376-381.
-
(1994)
Leukemia
, vol.8
, pp. 376-381
-
-
Todeschini, G.1
Meneghini, V.2
Pizzolo, G.3
-
26
-
-
0031951221
-
Estimated 6-year event-free survival of 55% in 60 consecutive adult acute lymphoblastic leukemia patients treated with an intensive phase II protocol based on high induction dose of daunorubicin
-
Todeschini G, Tecchio C, Meneghini V et al. Estimated 6-year event-free survival of 55% in 60 consecutive adult acute lymphoblastic leukemia patients treated with an intensive phase II protocol based on high induction dose of daunorubicin. Leukemia 1998: 12; 144-149.
-
(1998)
Leukemia
, vol.12
, pp. 144-149
-
-
Todeschini, G.1
Tecchio, C.2
Meneghini, V.3
-
27
-
-
0012483654
-
The modified hyper-CVAD regimen in newly diagnosed adult acute lymphoblastic leukemia (ALL)
-
abstract 2474
-
Thomas DA, Cortes J, Giles FJ et al. The modified hyper-CVAD regimen in newly diagnosed adult acute lymphoblastic leukemia (ALL). Blood 2001; 98: 590a. abstract 2474.
-
(2001)
Blood
, vol.98
-
-
Thomas, D.A.1
Cortes, J.2
Giles, F.J.3
-
28
-
-
0030013639
-
The novel anthracycline annamycin is not affected by P-glycoprotein-related multidrug resistance: Comparison with idarubicin and doxorubicin in HL-60 leukemia cell lines
-
Consoli U, Priebe W, Ling YH et al. The novel anthracycline annamycin is not affected by P-glycoprotein-related multidrug resistance: comparison with idarubicin and doxorubicin in HL-60 leukemia cell lines. Blood 1996; 88: 633-644.
-
(1996)
Blood
, vol.88
, pp. 633-644
-
-
Consoli, U.1
Priebe, W.2
Ling, Y.H.3
-
29
-
-
0028880010
-
Preclinical toxicity of liposome-incorporated annamycin: Selective bone marrow toxicity with lack of cardiotoxicity
-
Zou Y, Priebe W, Stephens LC & Perez-Soler R. Preclinical toxicity of liposome-incorporated annamycin: selective bone marrow toxicity with lack of cardiotoxicity. Clinical Cancer Research 1: 1995; 1369-1374.
-
(1995)
Clinical Cancer Research
, vol.1
, pp. 1369-1374
-
-
Zou, Y.1
Priebe, W.2
Stephens, L.C.3
Perez-Soler, R.4
-
30
-
-
4243467075
-
Phase I study of annamycin: A novel MDR-I independent anthracycline in relapsed/refractory AML
-
abstract 4212
-
Andreeff M, Giles R, Sanchez-Williams G et al. Phase I study of annamycin: a novel MDR-I independent anthracycline in relapsed/refractory AML. Blood 1999; 94: 226b. abstract 4212.
-
(1999)
Blood
, vol.94
-
-
Andreeff, M.1
Giles, R.2
Sanchez-Williams, G.3
-
31
-
-
0032605142
-
Mechanisms of methotrexate resistance in acute leukemia Decreased transport and polyglutamylation
-
Gorlick R, Cole P, Banerjee D et al. Mechanisms of methotrexate resistance in acute leukemia Decreased transport and polyglutamylation. Advances in Experimental Medicine and Biology 1999; 457: 543-550.
-
(1999)
Advances in Experimental Medicine and Biology
, vol.457
, pp. 543-550
-
-
Gorlick, R.1
Cole, P.2
Banerjee, D.3
-
32
-
-
0027484339
-
Multidrug resistance: Clinical relevance in acute leukemia
-
List AF. Multidrug resistance: clinical relevance in acute leukemia. Oncology (Huntington) 1993; 7: 23-28.
-
(1993)
Oncology (Huntington)
, vol.7
, pp. 23-28
-
-
List, A.F.1
-
33
-
-
0027314191
-
Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: Prognostic implications
-
Goasguen JE, Dossot JM, Fardel O et al. Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. Blood 1993; 81: 2394-2398.
-
(1993)
Blood
, vol.81
, pp. 2394-2398
-
-
Goasguen, J.E.1
Dossot, J.M.2
Fardel, O.3
-
34
-
-
0025302665
-
Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: A pilot prognostic factor analysis
-
Whitehead VM, Rosenblatt DS, Vuchich MJ et al. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis. Blood 1990; 76: 44-49.
-
(1990)
Blood
, vol.76
, pp. 44-49
-
-
Whitehead, V.M.1
Rosenblatt, D.S.2
Vuchich, M.J.3
-
35
-
-
0030756226
-
Differences in folylpolyglutamate synthetase and dihydrofolate reductase Expression in human B-lineage versus T-lineage leukemic lymphoblasts: Mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity
-
Galpin AJ, Schuetz JD, Masson E et al. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity. Molecular Pharmacology 1997; 52: 155-163.
-
(1997)
Molecular Pharmacology
, vol.52
, pp. 155-163
-
-
Galpin, A.J.1
Schuetz, J.D.2
Masson, E.3
-
36
-
-
0028063423
-
Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia
-
Synold TW, Relling MV, Boyett JM et al. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia. Journal of Clinical Investigation 1994; 94: 1996-2001.
-
(1994)
Journal of Clinical Investigation
, vol.94
, pp. 1996-2001
-
-
Synold, T.W.1
Relling, M.V.2
Boyett, J.M.3
-
37
-
-
0028800680
-
A phase II study of continuous infusion of trimetrexate in patients with refractory acute leukemia
-
Kheradpour A, Berman E, Goker E et al. A phase II study of continuous infusion of trimetrexate in patients with refractory acute leukemia. Cancer Investigation 1995; 13: 36-40.
-
(1995)
Cancer Investigation
, vol.13
, pp. 36-40
-
-
Kheradpour, A.1
Berman, E.2
Goker, E.3
-
39
-
-
0037096749
-
Trimetrexate in relapsed T-cell lymphoma with skin involvement
-
Sarris AH, Phan A, Duvic M et al. Trimetrexate in relapsed T-cell lymphoma with skin involvement. Journal of Clinical Oncology 2002; 20: 2876-2880.
-
(2002)
Journal of Clinical Oncology
, vol.20
, pp. 2876-2880
-
-
Sarris, A.H.1
Phan, A.2
Duvic, M.3
-
40
-
-
0031792644
-
Compound GW506U78 in refractory hematologic malignancies: Relationship between cellular pharmacokinetics and clinical response
-
Gandhi V, Plunkett W, Rodriguez CO Jr. et al. Compound GW506U78 in refractory hematologic malignancies: relationship between cellular pharmacokinetics and clinical response. Journal of Clinical Oncology 1998; 16: 3607-3615.
-
(1998)
Journal of Clinical Oncology
, vol.16
, pp. 3607-3615
-
-
Gandhi, V.1
Plunkett, W.2
Rodriguez C.O., Jr.3
-
41
-
-
0001462165
-
Compound 506 has activity in mature lymphoid leukemia
-
abstract 2022
-
O'Brien S, Thomas D, Kantarjian H et al. Compound 506 has activity in mature lymphoid leukemia. Blood 1998; 92: 490a. abstract 2022.
-
(1998)
Blood
, vol.92
-
-
O'Brien, S.1
Thomas, D.2
Kantarjian, H.3
-
42
-
-
0033999960
-
Pharmacokinetics of nelarabine and 9-beta-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies
-
Kisor DF, Plunkett W, Kurtzberg J et al. Pharmacokinetics of nelarabine and 9-beta-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies. Journal of Clinical Oncology 2000; 18: 995-1003.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 995-1003
-
-
Kisor, D.F.1
Plunkett, W.2
Kurtzberg, J.3
-
43
-
-
4243696026
-
A phase I study of 2-amino-9-b-D-arabinosyl-6-methoxy-9H-puine (nelarabine) administered on a consecutive five day schedule in children and adults with refractory hematologic malignancies
-
abstract 2794
-
Kurtzberg J, Ernst TJ, Keating MJ et al. A phase I study of 2-amino-9-b-D-arabinosyl-6-methoxy-9H-puine (nelarabine) administered on a consecutive five day schedule in children and adults with refractory hematologic malignancies. Blood 1999; 94: 699a. abstract 2794.
-
(1999)
Blood
, vol.94
-
-
Kurtzberg, J.1
Ernst, T.J.2
Keating, M.J.3
-
44
-
-
0035871440
-
Evaluation of the combination of nelarabine and fludarabine in leukemias: Clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells
-
Gandhi V, Plunkett W, Weller S et al. Evaluation of the combination of nelarabine and fludarabine in leukemias: clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells. Journal of Clinical Oncology 2001; 19: 2142-2152.
-
(2001)
Journal of Clinical Oncology
, vol.19
, pp. 2142-2152
-
-
Gandhi, V.1
Plunkett, W.2
Weller, S.3
-
45
-
-
0036317944
-
Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs-host disease: The role of dGTP in antiproliferative action of BCX-1777
-
Banti S, Miller PJ, Parker CD et al. Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs-host disease: the role of dGTP in antiproliferative action of BCX-1777. International Immunopharmacology 2002; 2: 913-923.
-
(2002)
International Immunopharmacology
, vol.2
, pp. 913-923
-
-
Banti, S.1
Miller, P.J.2
Parker, C.D.3
-
46
-
-
0035179950
-
DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine
-
Yamauchi T, Nowak BJ, Keating MJ & Plunkett W. DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine. Clinical Cancer Research 2001; 7: 3580-3589.
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 3580-3589
-
-
Yamauchi, T.1
Nowak, B.J.2
Keating, M.J.3
Plunkett, W.4
-
47
-
-
0003296548
-
Phase I and pharmacology study of clofarabine (2-Cl-2′-F-deoxy-9-D-arabino-furanosyladenine) in solid and hematologic cancers
-
Kantarjian HM, Gandhi VV, O'Brien S et al. Phase I and pharmacology study of clofarabine (2-Cl-2′-F-deoxy-9-D-arabino-furanosyladenine) in solid and hematologic cancers. Blood 2001; 98: 214b.
-
(2001)
Blood
, vol.98
-
-
Kantarjian, H.M.1
Gandhi, V.V.2
O'Brien, S.3
-
48
-
-
0012541145
-
Phase I study of clofarabine (Clofarex™) in pediatric leukemia
-
abstract 315
-
Jeha S, Gandhi V, Chan KW et al. Phase I study of clofarabine (Clofarex™) in pediatric leukemia. Blood 2002; 100: 86a. abstract 315.
-
(2002)
Blood
, vol.100
-
-
Jeha, S.1
Gandhi, V.2
Chan, K.W.3
-
49
-
-
0012535474
-
Clofarabine [2-chloro-9-(2-deoxy-2-fluoro- b-D-arabinofuranosyl) adenine is active for patients with refractory or relapsed acute leukemias, myelodysplastic syndromes (MDS) and chronic myeloid leukemia in blast phase (CML-BP)
-
abstract 739
-
Cortes JE, Gandhi V, Plunkett W et al. Clofarabine [2-chloro-9-(2-deoxy-2-fluoro- b-D-arabinofuranosyl) adenine is active for patients with refractory or relapsed acute leukemias, myelodysplastic syndromes (MDS) and chronic myeloid leukemia in blast phase (CML-BP). Blood 2002; 100: 197a. abstract 739.
-
(2002)
Blood
, vol.100
-
-
Cortes, J.E.1
Gandhi, V.2
Plunkett, W.3
-
50
-
-
0030029803
-
In vitro and in vivo inhibition of glioblastoma and neuroblastoma with MDL 101,731, a novel ribonucleoside diphosphate reductase inhibitor
-
Piepmeier JM, Rabidou N, Schold SC et al. In vitro and in vivo inhibition of glioblastoma and neuroblastoma with MDL 101,731, a novel ribonucleoside diphosphate reductase inhibitor. Cancer Research 1996; 56: 359-361.
-
(1996)
Cancer Research
, vol.56
, pp. 359-361
-
-
Piepmeier, J.M.1
Rabidou, N.2
Schold, S.C.3
-
51
-
-
0036140950
-
Action of (E)-2′-deoxy-2′-(fluoromethylene)cytidine on DNA metabolism: Incorporation, excision, and cellular response
-
Zhou Y, Achanta G, Pelicano H et al. Action of (E)-2′-deoxy-2′-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response. Molecular Pharmacology 2002; 61: 222-229.
-
(2002)
Molecular Pharmacology
, vol.61
, pp. 222-229
-
-
Zhou, Y.1
Achanta, G.2
Pelicano, H.3
-
52
-
-
18344398937
-
Decreased vascular endothelial growth factor expression associated with tumor regression induced by (E)-2′-deoxy-2′-(flouromethylene) cytidine (MDL 101,731)
-
Woessner RD, Loudy DE, Wallace CD et al. Decreased vascular endothelial growth factor expression associated with tumor regression induced by (E)-2′-deoxy-2′-(flouromethylene) cytidine (MDL 101,731). Oncologic Research 1997; 9: 543-552.
-
(1997)
Oncologic Research
, vol.9
, pp. 543-552
-
-
Woessner, R.D.1
Loudy, D.E.2
Wallace, C.D.3
-
53
-
-
79960970834
-
Phase I study of Tezacitabine (FMdC) in patients with relapsed and refractory hematologic malignancies
-
abstract 2493
-
Faderl S, Garcia-Manero G, Thomas DA et al. Phase I study of Tezacitabine (FMdC) in patients with relapsed and refractory hematologic malignancies. Blood 2001; 98: 595a. abstract 2493.
-
(2001)
Blood
, vol.98
-
-
Faderl, S.1
Garcia-Manero, G.2
Thomas, D.A.3
-
54
-
-
0030909701
-
DNA methylation changes in hematologic malignancies: Biologic and clinical implications
-
Issa JP, Baylin SB & Herman JG. DNA methylation changes in hematologic malignancies: Biologic and clinical implications. Leukemia 1997; 11: S7-S11.
-
(1997)
Leukemia
, vol.11
-
-
Issa, J.P.1
Baylin, S.B.2
Herman, J.G.3
-
55
-
-
0027243484
-
5-Aza-2′-deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: Past, present and future trends
-
Pinto A & Zagonel V. 5-Aza-2′-deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: past, present and future trends. Leukemia 1993; 7: 51-60.
-
(1993)
Leukemia
, vol.7
, pp. 51-60
-
-
Pinto, A.1
Zagonel, V.2
-
56
-
-
17444452612
-
Low-dose 5-aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients
-
Wijermans P, Lubbert M, Verhoef G et al. Low-dose 5-aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients. Journal of Clinical Oncology 2000; 18: 956-962.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 956-962
-
-
Wijermans, P.1
Lubbert, M.2
Verhoef, G.3
-
57
-
-
0027193132
-
Preliminary results with 5-aza-2′-deoxycytidine (DAC)-containing chemotherapy in patients with relapsed or refractory acute leukemia
-
The EORTC Leukemia Cooperative Group
-
Willemze R, Archimbaud E & Muus P. Preliminary results with 5-aza-2′-deoxycytidine (DAC)-containing chemotherapy in patients with relapsed or refractory acute leukemia. The EORTC Leukemia Cooperative Group. Leukemia 1993; 7: 49-50
-
(1993)
Leukemia
, vol.7
, pp. 49-50
-
-
Willemze, R.1
Archimbaud, E.2
Muus, P.3
-
58
-
-
0030990163
-
Decitabine (5-Aza-2′-deoxycytidine; DAC) plus daunorubicin as a first line treatment in patients with acute myeloid leukemia: Preliminary observations
-
Schwartsmann G, Fernandes MS, Schaan MD et al. Decitabine (5-Aza-2′-deoxycytidine; DAC) plus daunorubicin as a first line treatment in patients with acute myeloid leukemia: preliminary observations. Leukemia 1997; 11: S28-S31.
-
(1997)
Leukemia
, vol.11
-
-
Schwartsmann, G.1
Fernandes, M.S.2
Schaan, M.D.3
-
59
-
-
0035992430
-
DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia
-
Garcia-Manero G, Daniel J, Smith TL et al. DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia. Clinical Cancer Research 2002; 8: 2217-2224.
-
(2002)
Clinical Cancer Research
, vol.8
, pp. 2217-2224
-
-
Garcia-Manero, G.1
Daniel, J.2
Smith, T.L.3
-
60
-
-
0036278485
-
DNA methylation patterns at relapse in adult acute lymphocytic leukemia
-
Garcia-Manero G, Bueso-Ramos C, Daniel J et al. DNA methylation patterns at relapse in adult acute lymphocytic leukemia. Clinical Cancer Research 2002; 8: 1897-1903.
-
(2002)
Clinical Cancer Research
, vol.8
, pp. 1897-1903
-
-
Garcia-Manero, G.1
Bueso-Ramos, C.2
Daniel, J.3
-
61
-
-
0035884639
-
United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia
-
Soignet SL, Frankel SR, Douer D et al. United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia. Journal of Clinical Oncology 2001; 19: 3852-3860.
-
(2001)
Journal of Clinical Oncology
, vol.19
, pp. 3852-3860
-
-
Soignet, S.L.1
Frankel, S.R.2
Douer, D.3
-
62
-
-
0031691443
-
Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: Activation of caspases and down-regulation of Bcl-2 protein
-
Akao Y, Mizoguchi H, Kojima S et al. Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of caspases; and down-regulation of Bcl-2 protein. British Journal of Haematology 1998; 102: 1055-1060.
-
(1998)
British Journal of Haematology
, vol.102
, pp. 1055-1060
-
-
Akao, Y.1
Mizoguchi, H.2
Kojima, S.3
-
63
-
-
0032910345
-
Arsenic trioxide and interferon-alpha synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells
-
Bazarbachi A, El-Sabban ME, Nasr R et al. Arsenic trioxide and interferon-alpha synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells. Blood 1999; 93: 278-283.
-
(1999)
Blood
, vol.93
, pp. 278-283
-
-
Bazarbachi, A.1
El-Sabban, M.E.2
Nasr, R.3
-
64
-
-
18844477979
-
BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity
-
Puccetti E, Guller S, Orleth A et al. BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity. Cancer Research 2000; 60: 3409-3413.
-
(2000)
Cancer Research
, vol.60
, pp. 3409-3413
-
-
Puccetti, E.1
Guller, S.2
Orleth, A.3
-
65
-
-
0034743735
-
3 enhances selective cytotoxic effects of STI-571 against Bcr-Abl-positive acute leukemia cells
-
3 enhances selective cytotoxic effects of STI-571 against Bcr-Abl-positive acute leukemia cells. Leukemia 2001; 15: 772-778.
-
(2001)
Leukemia
, vol.15
, pp. 772-778
-
-
Porosnicu, M.1
Nimmanapalli, R.2
Nguyen, D.3
-
66
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Research 1999; 59: 2615-2622.
-
(1999)
Cancer Research
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
-
67
-
-
0003216241
-
Phase II study of PS-341, a novel proteasome inhibitor, alone or in combination with dexamethasone in patients with multiple myeloma who have relapsed following front-line therapy and are refractory to their most recent therapy
-
abstract 3223
-
Richardson PG, Berenson J, Irwin D et al. Phase II study of PS-341, a novel proteasome inhibitor, alone or in combination with dexamethasone in patients with multiple myeloma who have relapsed following front-line therapy and are refractory to their most recent therapy. Blood 2001; 98: 774a. abstract 3223.
-
(2001)
Blood
, vol.98
-
-
Richardson, P.G.1
Berenson, J.2
Irwin, D.3
-
68
-
-
0034015672
-
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
-
Waters JS, Webb A, Cunningham D et al. Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. Journal of Clinical Oncology 2000; 18: 1812-1823.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 1812-1823
-
-
Waters, J.S.1
Webb, A.2
Cunningham, D.3
-
69
-
-
0025264496
-
Bryostatin I, a unique biological response modifier: Antileukemic activity in vitro
-
Jones RJ, Sharkis SJ, Miller CB et al. Bryostatin I, a unique biological response modifier: antileukemic activity in vitro. Blood 1990; 75: 1319-1323.
-
(1990)
Blood
, vol.75
, pp. 1319-1323
-
-
Jones, R.J.1
Sharkis, S.J.2
Miller, C.B.3
-
70
-
-
0031982782
-
Phase I study of bryostatin I in patients with relapsed non-Hodgkin's lymphoma and chronic lymphocytic leukemia
-
Varterasian ML, Mohammad RM, Eilender DS et al. Phase I study of bryostatin I in patients with relapsed non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Journal of Clinical Oncology 1998; 16: 56-62.
-
(1998)
Journal of Clinical Oncology
, vol.16
, pp. 56-62
-
-
Varterasian, M.L.1
Mohammad, R.M.2
Eilender, D.S.3
-
71
-
-
0034851019
-
Phase II study of bryostatin I in patients with relapsed multiple myeloma
-
Varterasian ML, Pemberton PA, Hulburd K et al. Phase II study of bryostatin I in patients with relapsed multiple myeloma. Investigational New Drugs 2001; 19: 245-247.
-
(2001)
Investigational New Drugs
, vol.19
, pp. 245-247
-
-
Varterasian, M.L.1
Pemberton, P.A.2
Hulburd, K.3
-
72
-
-
12944249449
-
Phase II trial of bryostatin I in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia
-
Varterasian ML, Mohammad RM, Shurafa MS et al. Phase II trial of bryostatin I in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Clinical Cancer Research 2000; 6: 825-828.
-
(2000)
Clinical Cancer Research
, vol.6
, pp. 825-828
-
-
Varterasian, M.L.1
Mohammad, R.M.2
Shurafa, M.S.3
-
73
-
-
0033539938
-
Modulation of clAP-I by novel antitubulin agents when combined with bryostatin I results in increased apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh
-
Wall NR, Mohammad RM, Nabha SM et al. Modulation of clAP-I by novel antitubulin agents when combined with bryostatin I results in increased apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh. Biochemical and Biophysical Research Communications 1999; 266: 76-80.
-
(1999)
Biochemical and Biophysical Research Communications
, vol.266
, pp. 76-80
-
-
Wall, N.R.1
Mohammad, R.M.2
Nabha, S.M.3
-
74
-
-
0032877433
-
Bax:Bcl-2 ratio modulation by bryostatin I and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh
-
Wall NR, Mohammad RM & Al-Katib AM. Bax:Bcl-2 ratio modulation by bryostatin I and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh. Leukemia Research 1999; 23: 881-888.
-
(1999)
Leukemia Research
, vol.23
, pp. 881-888
-
-
Wall, N.R.1
Mohammad, R.M.2
Al-Katib, A.M.3
-
75
-
-
0034132418
-
Bryostatin I induces ubiquitination and proteasome degradation of Bcl-2 in the human acute lymphoblastic leukemia cell line, Reh
-
Wall NR, Mohammad RM, Reddy KB et al. Bryostatin I induces ubiquitination and proteasome degradation of Bcl-2 in the human acute lymphoblastic leukemia cell line, Reh. International Journal of Molecular Medicine 2000; 5: 165-171.
-
(2000)
International Journal of Molecular Medicine
, vol.5
, pp. 165-171
-
-
Wall, N.R.1
Mohammad, R.M.2
Reddy, K.B.3
-
76
-
-
0031059348
-
Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia
-
Perez-Atayde AR, Sallan SE, Tedrow U et al. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. American Journal of Pathology 1997; 150: 815-821.
-
(1997)
American Journal of Pathology
, vol.150
, pp. 815-821
-
-
Perez-Atayde, A.R.1
Sallan, S.E.2
Tedrow, U.3
-
77
-
-
85112389844
-
Human acute lymphoblastic leukemia promotes angiogenesis in vivo: Pre-clinical models to develop targeted intervention
-
abstract 484
-
Veiga JP, Sallan SE, Nadler LM & Cardoso AA. Human acute lymphoblastic leukemia promotes angiogenesis in vivo: pre-clinical models to develop targeted intervention. Blood 2000; 96. 113a. abstract 484.
-
(2000)
Blood
, vol.96
-
-
Veiga, J.P.1
Sallan, S.E.2
Nadler, L.M.3
Cardoso, A.A.4
-
78
-
-
0033107767
-
Inhibition of tumor growth, angiogenesis, and microcirculation by the novel flk-I inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy
-
Vajkoczy P, Menger MD, Vollmar B et al. Inhibition of tumor growth, angiogenesis, and microcirculation by the novel flk-I inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy. Neoplasia 1999; 1: 31-41.
-
(1999)
Neoplasia
, vol.1
, pp. 31-41
-
-
Vajkoczy, P.1
Menger, M.D.2
Vollmar, B.3
-
79
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-I/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
-
Fong TA, Shawver LK, Sun L et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-I/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Research 1999; 59: 99-106.
-
(1999)
Cancer Research
, vol.59
, pp. 99-106
-
-
Fong, T.A.1
Shawver, L.K.2
Sun, L.3
-
81
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
Carroll M, Ohno-Jones S, Tamura S et al. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood 1997; 90: 4947-4952.
-
(1997)
Blood
, vol.90
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
-
82
-
-
0029947186
-
Effects of a selective inhibitor of the ABL tyrosine kinase on the growth of BCR-ABL positive cells
-
Druker BJ, Tamura S, Buchdunger E et al. Effects of a selective inhibitor of the ABL tyrosine kinase on the growth of BCR-ABL positive cells. Nature Medicine 1996; 2: 561-566.
-
(1996)
Nature Medicine
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
83
-
-
15444350807
-
Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148)
-
Beran M, Cao, X, Estrov Z et al. Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCR-ABL protein by a tyrosine kinase inhibitor (CGP-57148). Clinical Cancer Research 1998; 4: 1661-1672.
-
(1998)
Clinical Cancer Research
, vol.4
, pp. 1661-1672
-
-
Beran, M.1
Cao, X.2
Estrov, Z.3
-
84
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. New England Journal of Medicine 2001; 344. 1038-1042.
-
(2001)
New England Journal of Medicine
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
-
85
-
-
0037105560
-
A phase II study of imatinib mesylate (Glivec) in patients with relapsed or refractory Philadelphia chromosome positive acute lymphoid leukemias
-
Ottmann OG, Druker BJ, Sawyers CL et al. A phase II study of imatinib mesylate (Glivec) in patients with relapsed or refractory Philadelphia chromosome positive acute lymphoid leukemias. Blood 2002; 100: 1965-1971.
-
(2002)
Blood
, vol.100
, pp. 1965-1971
-
-
Ottmann, O.G.1
Druker, B.J.2
Sawyers, C.L.3
-
86
-
-
0003285566
-
Combination of hyper-CVAD with imatinib mesylate (STI571) for Philadelphia (Ph)-positive adult acute lymphoblastic leukemia (ALL) or chronic myelogenous leukemia in lymphoid blast phase (CML-LBP)
-
abstract 3340
-
Thomas DA, Cortes J, Giles FJ et al. Combination of hyper-CVAD with imatinib mesylate (STI571) for Philadelphia (Ph)-positive adult acute lymphoblastic leukemia (ALL) or chronic myelogenous leukemia in lymphoid blast phase (CML-LBP). Blood 2001; 98: 803a. abstract 3340.
-
(2001)
Blood
, vol.98
-
-
Thomas, D.A.1
Cortes, J.2
Giles, F.J.3
-
87
-
-
0037045589
-
Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: A gene-expression study
-
Hofmann WK, de Vos S, Elashoff D et al. Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study. Lancet 2002; 359: 481-486.
-
(2002)
Lancet
, vol.359
, pp. 481-486
-
-
Hofmann, W.K.1
de Vos, S.2
Elashoff, D.3
-
88
-
-
0036493544
-
Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation
-
Hofmann WK, Jones LC, Lemp NA et al. Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation. Blood 2002; 99: 1860-1862.
-
(2002)
Blood
, vol.99
, pp. 1860-1862
-
-
Hofmann, W.K.1
Jones, L.C.2
Lemp, N.A.3
-
89
-
-
0033387144
-
Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosis-inducing CD19-directed tyrosine kinase inhibitor
-
Uckun FM, Messinger Y, Chen CL et al. Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosis-inducing CD19-directed tyrosine kinase inhibitor. Clinical Cancer Research 1999; 5: 3906-3913.
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 3906-3913
-
-
Uckun, F.M.1
Messinger, Y.2
Chen, C.L.3
-
90
-
-
0021813140
-
Reactivity of rat monoclonal antibody CAMPATH-I with human leukemia cells and its possible application for autologous bone marrow transplantation
-
Hale G, Swirsky D, Waldmann H et al. Reactivity of rat monoclonal antibody CAMPATH-I with human leukemia cells and its possible application for autologous bone marrow transplantation. British Journal of Haematology 1985; 60: 41-48.
-
(1985)
British Journal of Haematology
, vol.60
, pp. 41-48
-
-
Hale, G.1
Swirsky, D.2
Waldmann, H.3
-
91
-
-
0024566393
-
Effects of Campath-IH antibodies in vivo in patients with lymphoid malignancies: Influence of antibody isotype
-
Dyer MJ, Hale G, Hayhoe FGJ et al. Effects of Campath-IH antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype. Blood 1989; 73: 1431-1439.
-
(1989)
Blood
, vol.73
, pp. 1431-1439
-
-
Dyer, M.J.1
Hale, G.2
Hayhoe, F.G.J.3
-
92
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-IH) in patients who have failed fludarabine: Results of a large international study
-
Keating MJ, Flinn I, Jain V et al. Therapeutic role of alemtuzumab (Campath-IH) in patients who have failed fludarabine: results of a large international study. Blood 2000; 99: 3554-3561.
-
(2000)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
-
93
-
-
0032719863
-
Preclinical and phase I and II trials of rituximab
-
Maloney DG. Preclinical and phase I and II trials of rituximab. Seminars in Oncology 1999; 26: 74-78.
-
(1999)
Seminars in Oncology
, vol.26
, pp. 74-78
-
-
Maloney, D.G.1
-
94
-
-
0345337254
-
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
-
McLaughlin P, Grillo-Lopez AJ, Link BK et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. Journal of Clinical Oncology 1998; 16: 2825-2833.
-
(1998)
Journal of Clinical Oncology
, vol.16
, pp. 2825-2833
-
-
McLaughlin, P.1
Grillo-Lopez, A.J.2
Link, B.K.3
-
95
-
-
0003259284
-
Chemokine upregulation in response to rituximab in B-cell non-Hodgkin's lymphoma
-
abstract 377
-
Ansell SM, Tschumper RC, Witzig TE et al. Chemokine upregulation in response to rituximab in B-cell non-Hodgkin's lymphoma. Blood 1999; 94: 86a. abstract 377.
-
(1999)
Blood
, vol.94
-
-
Ansell, S.M.1
Tschumper, R.C.2
Witzig, T.E.3
-
96
-
-
0344766075
-
Treatment of low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy
-
Czuczman MS, Grillo-Lopez AJ, White CA et al. Treatment of low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy. Journal of Clinical Oncology 1999; 17: 268-276.
-
(1999)
Journal of Clinical Oncology
, vol.17
, pp. 268-276
-
-
Czuczman, M.S.1
Grillo-Lopez, A.J.2
White, C.A.3
-
97
-
-
0037165261
-
CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma
-
Coiffier B, Lepage E, Briere J et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. New England Journal of Medicine 2002; 346: 235-242.
-
(2002)
New England Journal of Medicine
, vol.346
, pp. 235-242
-
-
Coiffier, B.1
Lepage, E.2
Briere, J.3
-
98
-
-
85112374294
-
Significance of CD20 positivity in de novo acute lymphocytic leukemia (ALL)
-
abstract 468
-
Thomas DA, Cortes J, O'Brien SM et al. Significance of CD20 positivity in de novo acute lymphocytic leukemia (ALL). Blood 2000; 96: 109a. abstract 468.
-
(2000)
Blood
, vol.96
-
-
Thomas, D.A.1
Cortes, J.2
O'Brien, S.M.3
-
99
-
-
79960971206
-
Rituximab and hyper-CVAD for adult Burkitt's (BL) or Burkitt's-like (BLL) leukemia or lymphoma
-
abstract 3342
-
Thomas DA, Cortes J, Giles FJ et al. Rituximab and hyper-CVAD for adult Burkitt's (BL) or Burkitt's-like (BLL) leukemia or lymphoma. Blood 2001; 98: 804a. abstract 3342.
-
(2001)
Blood
, vol.98
-
-
Thomas, D.A.1
Cortes, J.2
Giles, F.J.3
-
100
-
-
0020606415
-
B4, a human B lymphocyte associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes
-
Nadler LM, Anderson KC, Marti G et al. B4, a human B lymphocyte associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes. Journal of Immunology 1983; 131: 244-250.
-
(1983)
Journal of Immunology
, vol.131
, pp. 244-250
-
-
Nadler, L.M.1
Anderson, K.C.2
Marti, G.3
-
101
-
-
0027502253
-
Anti-B4-blocked ricin: A phase I trial of 7-day continuous infusion in patients with B-cell neoplasms
-
Grossbard ML, Lambert JM, Goldmacher VS et al. Anti-B4-blocked ricin: a phase I trial of 7-day continuous infusion in patients with B-cell neoplasms. Journal of Clinical Oncology 1993; 11: 726-737.
-
(1993)
Journal of Clinical Oncology
, vol.11
, pp. 726-737
-
-
Grossbard, M.L.1
Lambert, J.M.2
Goldmacher, V.S.3
-
102
-
-
0031685787
-
Treatment of human B-cell precursor leukemia in SCID mice by using a combination of the anti-CD19 immunotoxin B43-PAP with the standard chemotherapeutic drugs vincristine, methylprednisolone, and I-asparaginase
-
Ek O, Gaynon P, Zeren T et al. Treatment of human B-cell precursor leukemia in SCID mice by using a combination of the anti-CD19 immunotoxin B43-PAP with the standard chemotherapeutic drugs vincristine, methylprednisolone, and I-asparaginase. Leukemia and Lymphoma 1998; 31: 143-149.
-
(1998)
Leukemia and Lymphoma
, vol.31
, pp. 143-149
-
-
Ek, O.1
Gaynon, P.2
Zeren, T.3
-
103
-
-
0034090987
-
Immunotoxins against CD19 and CD22 are effective in killing precursor-B acute lymphoblastic leukemia cells in vitro
-
Herrera L, Farah RA, Pellegrini VA et al. Immunotoxins against CD19 and CD22 are effective in killing precursor-B acute lymphoblastic leukemia cells in vitro. Leukemia 2000; 14: 853-858.
-
(2000)
Leukemia
, vol.14
, pp. 853-858
-
-
Herrera, L.1
Farah, R.A.2
Pellegrini, V.A.3
-
104
-
-
0027394952
-
In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia/lymphoma in mice with severe combined immunodeficiency
-
Gunther R, Chelstrom LM, Finnegan D et al. In vivo anti-leukemic efficacy of anti-CD7-pokeweed antiviral protein immunotoxin against human T-lineage acute lymphoblastic leukemia/lymphoma in mice with severe combined immunodeficiency. Leukemia 1993; 7: 298-309.
-
(1993)
Leukemia
, vol.7
, pp. 298-309
-
-
Gunther, R.1
Chelstrom, L.M.2
Finnegan, D.3
-
105
-
-
0012534761
-
BL22, an anti-CD22 recombinant immunotoxin, is active in vitro and in vivo against B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells from pediatric patients
-
abstract 3024
-
Lew G, Gu L, Zhou M et al. BL22, an anti-CD22 recombinant immunotoxin, is active in vitro and in vivo against B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells from pediatric patients. Blood 2002; 100: 764a. abstract 3024.
-
(2002)
Blood
, vol.100
-
-
Lew, G.1
Gu, L.2
Zhou, M.3
-
106
-
-
0033151526
-
Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: A phase I study of an anti-CD33 calicheamicin immunoconjugate
-
Sievers EL, Appelbaum FA, Spielberger RT et al. Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate. Blood 1999; 93: 3678-3684.
-
(1999)
Blood
, vol.93
, pp. 3678-3684
-
-
Sievers, E.L.1
Appelbaum, F.A.2
Spielberger, R.T.3
-
107
-
-
0036733277
-
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)
-
Larson RA, Boogaerts M, Estey E et al. Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). Leukemia 2002; 16: 1627-1636.
-
(2002)
Leukemia
, vol.16
, pp. 1627-1636
-
-
Larson, R.A.1
Boogaerts, M.2
Estey, E.3
-
108
-
-
0035878068
-
Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation
-
Giles FJ, Kantarjian HM, Kornblau SM et al. Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation. Cancer 2001; 92: 406-413.
-
(2001)
Cancer
, vol.92
, pp. 406-413
-
-
Giles, F.J.1
Kantarjian, H.M.2
Kornblau, S.M.3
-
109
-
-
0036182540
-
Immunotherapy of non-Hodgkin's lymphoma with hLL2 (epratuzumab, an anti-CD22 monoclonal antibody) and HuID10 (apolizumab)
-
Leonard JP & Link BK. Immunotherapy of non-Hodgkin's lymphoma with hLL2 (epratuzumab, an anti-CD22 monoclonal antibody) and HuID10 (apolizumab). Seminars in Oncology 2002; 29: 81-86.
-
(2002)
Seminars in Oncology
, vol.29
, pp. 81-86
-
-
Leonard, J.P.1
Link, B.K.2
-
110
-
-
0035992309
-
In vivo pharmacodynamic effects of HuID10 (remitogen), a humanized antibody reactive against a polymorphic determinant of HLA-DR expressed on B cells
-
Shi JD, Bullock C, Hall WC et al. In vivo pharmacodynamic effects of HuID10 (remitogen), a humanized antibody reactive against a polymorphic determinant of HLA-DR expressed on B cells. Leukemia and Lymphoma 2002; 43: 1303-1312.
-
(2002)
Leukemia and Lymphoma
, vol.43
, pp. 1303-1312
-
-
Shi, J.D.1
Bullock, C.2
Hall, W.C.3
-
111
-
-
0003351083
-
Phase I trial of humanized ID10 (HUID10) monoclonal antibody targeting class II molecules in patients with relapsed lymphoma
-
abstract 86
-
Link BK, Wang H, Byrd JC et al. Phase I trial of humanized ID10 (HUID10) monoclonal antibody targeting class II molecules in patients with relapsed lymphoma. Proceedings of the American Society of Clinical Oncology 2000; 19: 24a. abstract 86
-
(2000)
Proceedings of the American Society of Clinical Oncology
, vol.19
-
-
Link, B.K.1
Wang, H.2
Byrd, J.C.3
-
112
-
-
19044399684
-
Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
-
Yeoh EJ, Ross ME, Shurtleff SA et al. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 2002; 1: 133-143.
-
(2002)
Cancer Cell
, vol.1
, pp. 133-143
-
-
Yeoh, E.J.1
Ross, M.E.2
Shurtleff, S.A.3
-
113
-
-
17144474314
-
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
-
Ferrando AA, Neuberg DS, Staunton J et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 2002; 1: 75-87.
-
(2002)
Cancer Cell
, vol.1
, pp. 75-87
-
-
Ferrando, A.A.1
Neuberg, D.S.2
Staunton, J.3
|