-
1
-
-
0027452349
-
Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny
-
Uckun, F. M., Burkhardt, A. L., Jarvis, L., Jun, X., Stealey, B., Dibirdik, I., Myers, D. E., Tuel Ahlgren, L., and Bolen, J. B. Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny. J. Biol. Chem., 268: 21172-21184, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21172-21184
-
-
Uckun, F.M.1
Burkhardt, A.L.2
Jarvis, L.3
Jun, X.4
Stealey, B.5
Dibirdik, I.6
Myers, D.E.7
Tuel Ahlgren, L.8
Bolen, J.B.9
-
2
-
-
0023864495
-
Detailed studies on expression and function of CD19 surface determinant by using B43 monoclonal antibody and the clinical potential of anti- CD19 immunotoxins
-
Uckun, F. M., Jaszcz, W., Ambrus, J. L., Fauci, A. S., Gajl-Peczalska, K., Song, C. W., Wick, M. R., Myers, D. E., Waddick, K., and Ledbetter, J. A. Detailed studies on expression and function of CD19 surface determinant by using B43 monoclonal antibody and the clinical potential of anti- CD19 immunotoxins. Blood, 71: 13-29, 1988.
-
(1988)
Blood
, vol.71
, pp. 13-29
-
-
Uckun, F.M.1
Jaszcz, W.2
Ambrus, J.L.3
Fauci, A.S.4
Gajl-Peczalska, K.5
Song, C.W.6
Wick, M.R.7
Myers, D.E.8
Waddick, K.9
Ledbetter, J.A.10
-
3
-
-
0022576064
-
Use of a novel colony assay to evaluate the cytotoxicity of an immunotoxin containing pokeweed antiviral protein against blast progenitor cells freshly obtained from patients with common B-lineage acute lymphoblastic leukemia
-
Uckun, F. M., Gajl-Peczalska, K. J., Kersey, J. H., Houston, L. L., and Vallera, D. A. Use of a novel colony assay to evaluate the cytotoxicity of an immunotoxin containing pokeweed antiviral protein against blast progenitor cells freshly obtained from patients with common B-lineage acute lymphoblastic leukemia. J. Exp. Med., 163: 347-368, 1986.
-
(1986)
J. Exp. Med.
, vol.163
, pp. 347-368
-
-
Uckun, F.M.1
Gajl-Peczalska, K.J.2
Kersey, J.H.3
Houston, L.L.4
Vallera, D.A.5
-
4
-
-
0025243360
-
Regulation of human B-cell ontogeny
-
Uckun, F. M. Regulation of human B-cell ontogeny (Review). Blood, 76: 1908-1923, 1990.
-
(1990)
Blood
, vol.76
, pp. 1908-1923
-
-
Uckun, F.M.1
-
5
-
-
0030970798
-
+ acute lymphoblastic leukemia: A Children's Cancer Group study
-
+ acute lymphoblastic leukemia: a Children's Cancer Group study. Blood, 89: 2488-2493, 1997.
-
(1997)
Blood
, vol.89
, pp. 2488-2493
-
-
Uckun, F.M.1
Gaynon, P.2
Sather, H.3
Arthur, D.4
Trigg, M.5
Tubergen, D.6
Nachman, J.7
Sensel, M.G.8
Reaman, G.R.9
-
6
-
-
0030997662
-
Clinical features and treatment outcome of children with myeloid antigen positive acute lymphoblastic leukemia: A report from the Children's Cancer Group
-
Uckun, F. M., Sather, H., Gaynon, P., Arthur, D., Trigg, M., Tubergen, D., Nachman, J., Steinherz, P., Sensel, M., and Reaman, G. Clinical features and treatment outcome of children with myeloid antigen positive acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood, 90: 28-35, 1997.
-
(1997)
Blood
, vol.90
, pp. 28-35
-
-
Uckun, F.M.1
Sather, H.2
Gaynon, P.3
Arthur, D.4
Trigg, M.5
Tubergen, D.6
Nachman, J.7
Steinherz, P.8
Sensel, M.9
Reaman, G.10
-
7
-
-
0031918423
-
Clinical significance of translocation t(1;19) in childhood acute lymphoblastic leukemia in the context of contemporary therapies: A report from the Children's Cancer Group
-
Uckun, F. M., Sensel, M. G., Sather, H. N., Gaynon, P. S., Arthur, D. C., Lange, B. J., Steinherz, P. G., Kraft, P., Hutchinson, R., Nachman, J. B., Reaman, G. H., and Heerema, N. A. Clinical significance of translocation t(1;19) in childhood acute lymphoblastic leukemia in the context of contemporary therapies: a report from the Children's Cancer Group. J. Clin. Oncol., 16: 527-535, 1998.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 527-535
-
-
Uckun, F.M.1
Sensel, M.G.2
Sather, H.N.3
Gaynon, P.S.4
Arthur, D.C.5
Lange, B.J.6
Steinherz, P.G.7
Kraft, P.8
Hutchinson, R.9
Nachman, J.B.10
Reaman, G.H.11
Heerema, N.A.12
-
8
-
-
0028985934
-
Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases
-
Uckun, F. M., Evans, W. E., Forsyth, C. J., Waddick, K. G., Ahlgren, L. T., Chelstrom, L. M., Burkhardt, A., Bolen, J., and Myers, D. E. Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases. Science (Washington DC), 267: 886-891, 1995.
-
(1995)
Science (Washington DC)
, vol.267
, pp. 886-891
-
-
Uckun, F.M.1
Evans, W.E.2
Forsyth, C.J.3
Waddick, K.G.4
Ahlgren, L.T.5
Chelstrom, L.M.6
Burkhardt, A.7
Bolen, J.8
Myers, D.E.9
-
9
-
-
0028846718
-
Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cells
-
published erratum appears in Proc. Natl. Acad. Sci. USA 1996 Feb. 6; 93:1357
-
Myers, D. E., Jun, X., Waddick, K. G., Forsyth, C., Chelstrom, L. M., Gunther, R. L., Tumer, N. E., Bolen, J., and Uckun, F. M. Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cells (published erratum appears in Proc. Natl. Acad. Sci. USA 1996 Feb. 6; 93:1357). Proc. Natl. Acad. Sci. USA, 92: 9575-9579, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9575-9579
-
-
Myers, D.E.1
Jun, X.2
Waddick, K.G.3
Forsyth, C.4
Chelstrom, L.M.5
Gunther, R.L.6
Tumer, N.E.7
Bolen, J.8
Uckun, F.M.9
-
10
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine-specific protein kinases
-
Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S., Itoh, N., Shibuya, M., and Fukami, Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem., 262: 5592-5595, 1987.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishida, J.2
Nakagawa, S.3
Ogawara, H.4
Watanabe, S.5
Itoh, N.6
Shibuya, M.7
Fukami, Y.8
-
11
-
-
7344234242
-
In vivo toxicity and pharmacokinetic features of B43(Anti-CD19)-genistein immunoconjugate
-
Ek, O., Yanishevski, Y., Zeren, T., Waurzyniak, B., Gunther, R., Chelstrom, L., Chandan-Langlie, M., Schneider, E., Myers, D. E., Evans, W., and Uckun, F. M. In vivo toxicity and pharmacokinetic features of B43(Anti-CD19)-genistein immunoconjugate. Leuk. Lymphoma, 30: 389-394, 1998.
-
(1998)
Leuk. Lymphoma
, vol.30
, pp. 389-394
-
-
Ek, O.1
Yanishevski, Y.2
Zeren, T.3
Waurzyniak, B.4
Gunther, R.5
Chelstrom, L.6
Chandan-Langlie, M.7
Schneider, E.8
Myers, D.E.9
Evans, W.10
Uckun, F.M.11
-
12
-
-
0031907401
-
In vivo toxicity and pharmacokinetic features of B43(anti-CD19)-genistein immunoconjugate in non-human primates
-
Messinger, Y., Yanishevski, Y., Ek, O., Zeren, T., Waurzyniak, B., Gunther, R., Chelstrom, L., Chandan-Langlie, M., Schneider, E., Myers, D. E., Evans, W., and Uckun, F. M. In vivo toxicity and pharmacokinetic features of B43(anti-CD19)-genistein immunoconjugate in non-human primates. Clin. Cancer Res., 4: 165-170, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 165-170
-
-
Messinger, Y.1
Yanishevski, Y.2
Ek, O.3
Zeren, T.4
Waurzyniak, B.5
Gunther, R.6
Chelstrom, L.7
Chandan-Langlie, M.8
Schneider, E.9
Myers, D.E.10
Evans, W.11
Uckun, F.M.12
-
13
-
-
0031820228
-
Large scale manufacturing of B43(anti-CD19)-genistein for clinical trials in leukemia and lymphoma
-
Myers, D. E., Sicheneder, A., Clementson, D., Dvorak, N., Venkatachalam, T., Rostovsev, A., Chandan-Langlie, M., and Uckun, F. M. Large scale manufacturing of B43(anti-CD19)-genistein for clinical trials in leukemia and lymphoma. Leuk. Lymphoma, 29: 329-338, 1998.
-
(1998)
Leuk. Lymphoma
, vol.29
, pp. 329-338
-
-
Myers, D.E.1
Sicheneder, A.2
Clementson, D.3
Dvorak, N.4
Venkatachalam, T.5
Rostovsev, A.6
Chandan-Langlie, M.7
Uckun, F.M.8
-
14
-
-
0032908020
-
Pharmacokinetics and biologic activity of the novel mast cell inhibitor, 4-(3-hydroxphenyl)-amino-6,7-dimethoxyquinazoline in mice
-
Chen, C. L., Malaviya, R., Navara, C., Chen, H., Bechard, B., Mitcheltree, G., Liu, X. P., and Uckun, F. M. Pharmacokinetics and biologic activity of the novel mast cell inhibitor, 4-(3-hydroxphenyl)-amino-6,7-dimethoxyquinazoline in mice. Pharm. Res., 16: 117-122, 1999.
-
(1999)
Pharm. Res.
, vol.16
, pp. 117-122
-
-
Chen, C.L.1
Malaviya, R.2
Navara, C.3
Chen, H.4
Bechard, B.5
Mitcheltree, G.6
Liu, X.P.7
Uckun, F.M.8
-
15
-
-
0030933719
-
Pharmacokinetic features, immunogenicity, and toxicity of B43(anti- CD19)-pokeweed antiviral protein immunotoxin in cynomolgus monkeys
-
Uckun, F. M., Yanishevski, Y., Tumer, N., Waurzyniak, B., Messinger, Y., Chelstrom, L. M., Lisowski, E. A., Ek, O., Zeren, T., Wendorf, H., Langlie, M. C., Irvin, J. D., Myers, D. E., Fuller, G. B., Evans, W., and Gunther, R. Pharmacokinetic features, immunogenicity, and toxicity of B43(anti- CD19)-pokeweed antiviral protein immunotoxin in cynomolgus monkeys. Clin. Cancer Res., 3: 325-337, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 325-337
-
-
Uckun, F.M.1
Yanishevski, Y.2
Tumer, N.3
Waurzyniak, B.4
Messinger, Y.5
Chelstrom, L.M.6
Lisowski, E.A.7
Ek, O.8
Zeren, T.9
Wendorf, H.10
Langlie, M.C.11
Irvin, J.D.12
Myers, D.E.13
Fuller, G.B.14
Evans, W.15
Gunther, R.16
-
16
-
-
0029850505
-
In vivo pharmacology and anti-tumor evaluation of the tryphostin tyrosine kinase inhibitor RG13022
-
Mcleod, H. L., Brunton, V. G., Eckardt, N., Lear, M. J., Robins, D. J., Workman, P., and Graham, M. A. In vivo pharmacology and anti-tumor evaluation of the tryphostin tyrosine kinase inhibitor RG13022. Br. J. Cancer, 74: 1714-1718, 1996.
-
(1996)
Br. J. Cancer
, vol.74
, pp. 1714-1718
-
-
Mcleod, H.L.1
Brunton, V.G.2
Eckardt, N.3
Lear, M.J.4
Robins, D.J.5
Workman, P.6
Graham, M.A.7
-
17
-
-
0029999052
-
Phase I clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
-
Ferry, D. R., Smith, A., Malkhandi, J., Fyfe, D. W., deTakats, P. G., Anderson, D., Baker, J., and Kerr, D. J. Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin. Cancer Res., 2: 659-668, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 659-668
-
-
Ferry, D.R.1
Smith, A.2
Malkhandi, J.3
Fyfe, D.W.4
DeTakats, P.G.5
Anderson, D.6
Baker, J.7
Kerr, D.J.8
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